Gene Gene information from NCBI Gene database.
Entrez ID 51747
Gene name LUC7 like 3 pre-mRNA splicing factor
Gene symbol LUC7L3
Synonyms (NCBI Gene)
CRACREAP-1CROPLUC7AOA48-18hLuc7A
Chromosome 17
Chromosome location 17q21.33
Summary This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This
miRNA miRNA information provided by mirtarbase database.
360
miRTarBase ID miRNA Experiments Reference
MIRT020883 hsa-miR-155-5p Proteomics 18668040
MIRT045993 hsa-miR-125b-5p CLASH 23622248
MIRT041706 hsa-miR-484 CLASH 23622248
MIRT040591 hsa-miR-92b-3p CLASH 23622248
MIRT449190 hsa-miR-15a-5p PAR-CLIP 22100165
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003729 Function MRNA binding IBA
GO:0003729 Function MRNA binding IEA
GO:0003729 Function MRNA binding IMP 10631324
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609434 24309 ENSG00000108848
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95232
Protein name Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
Protein function Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03194 LUC7 3 295 LUC7 N_terminus Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in
Sequence
Sequence length 432
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Acute myeloid leukemia Uncertain significance rs369622093 RCV005927230
Clear cell carcinoma of kidney Uncertain significance rs369622093 RCV005927231
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 32497068
Carcinoma Renal Cell Associate 24899691
Death Sudden Associate 21859973
Head and Neck Neoplasms Associate 22986368
Heart Failure Associate 21859973, 22939879
Hypoxia Stimulate 22939879
Nasopharyngeal Carcinoma Associate 22986368
Neoplasms Associate 22986368, 34001978
Prostatic Neoplasms Associate 37143720