ARID4B (AT-rich interaction domain 4B)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51742 |
| Gene name | AT-rich interaction domain 4B |
| Gene symbol | ARID4B |
| Synonyms (NCBI Gene) |
BCAABRCAA1RBBP1L1RBP1L1SAP180
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| Chromosome | 1 |
| Chromosome location | 1q42.3 |
| Summary | This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes includ |
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miRNA
miRNA information provided by mirtarbase database.
658
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q4LE39 | ||||||||||||||||||||
| Protein name | AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinobla | ||||||||||||||||||||
| Protein function | Acts as a transcriptional repressor (PubMed:12724404). May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (PubMed:12724404). Pla | ||||||||||||||||||||
| PDB | 7DM4 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary. {ECO:0000269|PubMed:11481388, ECO:0000269|PubMed:12724404, ECO:0000269|PubMed:1524712 | ||||||||||||||||||||
| Sequence |
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| Sequence length | 1312 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
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