Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51705
Gene name Gene Name - the full gene name approved by the HGNC.
Endomucin
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
EMCN
Synonyms (NCBI Gene) Gene synonyms aliases
EMCN2, MUC14
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q24
Summary Summary of gene provided in NCBI Entrez Gene.
EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019151 hsa-miR-335-5p Microarray 18185580
MIRT711180 hsa-miR-3183 HITS-CLIP 19536157
MIRT711179 hsa-miR-4723-3p HITS-CLIP 19536157
MIRT711178 hsa-miR-6769b-3p HITS-CLIP 19536157
MIRT636583 hsa-miR-1248 HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
GO:0005886 Component Plasma membrane IEA
GO:0016020 Component Membrane IEA
GO:0061484 Process Hematopoietic stem cell homeostasis IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608350 16041 ENSG00000164035
Protein
UniProt ID Q9ULC0
Protein name Endomucin (Endomucin-2) (Gastric cancer antigen Ga34) (Mucin-14) (MUC-14)
Protein function Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07010 Endomucin 1 261 Endomucin Family
Tissue specificity TISSUE SPECIFICITY: Expressed in heart, kidney and lung. {ECO:0000269|PubMed:11418125, ECO:0000269|PubMed:12485444}.
Sequence
Sequence length 261
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Astrocytoma Pilocytic astrocytoma N/A N/A GWAS
Eosinophilia Eosinophilic esophagitis N/A N/A GWAS
Insomnia Insomnia N/A N/A GWAS
Ischemic Stroke Ischemic stroke N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenoma Associate 24099521
Angiolipoma Associate 12485444
Breast Neoplasms Associate 34828282, 37551622
Carcinoma Hepatocellular Associate 32644941
Carcinoma Renal Cell Associate 35624190
Granuloma Pyogenic Associate 12485444
Hemangiosarcoma Associate 12485444
Idiopathic Pulmonary Fibrosis Associate 35092415
Lichen Planus Associate 12485444
Lung Neoplasms Associate 35092415