Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51642
Gene name Gene Name - the full gene name approved by the HGNC.	Mitochondrial ribosomal protein L48
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MRPL48
Synonyms (NCBI Gene) Gene synonyms aliases	CGI-118, HSPC290, L48MT, MRP-L48, mL48
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q13.4
Summary Summary of gene provided in NCBI Entrez Gene.	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot

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miRTarBase ID	miRNA	Experiments
MIRT2274768	hsa-miR-1224-5p	CLIP-seq
MIRT2274769	hsa-miR-1225-5p	CLIP-seq
MIRT2274770	hsa-miR-1271	CLIP-seq
MIRT2274771	hsa-miR-182	CLIP-seq
MIRT2274772	hsa-miR-193a-3p	CLIP-seq
MIRT2274773	hsa-miR-193b	CLIP-seq
MIRT2274774	hsa-miR-323-3p	CLIP-seq
MIRT2274775	hsa-miR-3622b-5p	CLIP-seq
MIRT2274776	hsa-miR-4506	CLIP-seq
MIRT2274777	hsa-miR-4517	CLIP-seq
MIRT2274778	hsa-miR-4720-5p	CLIP-seq
MIRT2274779	hsa-miR-4751	CLIP-seq
MIRT2274780	hsa-miR-4753-3p	CLIP-seq
MIRT2274781	hsa-miR-4794	CLIP-seq
MIRT2274782	hsa-miR-4799-3p	CLIP-seq
MIRT2274783	hsa-miR-892b	CLIP-seq
MIRT2274784	hsa-miR-9	CLIP-seq
MIRT2274785	hsa-miR-942	CLIP-seq
MIRT2274786	hsa-miR-96	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	20601428
GO:0005739	Component	Mitochondrion	IDA	28892042
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005761	Component	Mitochondrial ribosome	IBA	21873635
GO:0005761	Component	Mitochondrial ribosome	IDA	20601428
GO:0005762	Component	Mitochondrial large ribosomal subunit	IDA	25278503, 28892042
GO:0070125	Process	Mitochondrial translational elongation	TAS
GO:0070126	Process	Mitochondrial translational termination	TAS

MIM	HGNC	e!Ensembl
611853	16653	ENSG00000175581

Protein

UniProt ID

Q96GC5

Protein name

Large ribosomal subunit protein mL48 (39S ribosomal protein L48, mitochondrial) (L48mt) (MRP-L48)

PDB

3J7Y , 3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF0 , 7OF2 , 7OF3 , 7OF4 , 7OF5 , 7OF6 , 7OF7 , 7OG4 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4 , 7QH7 , 7QI4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00338	Ribosomal_S10	92 → 187	Ribosomal protein S10p/S20e	Family

Sequence

MSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYK
HLIKAEEPKKKKGKVEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIK
VEESYAMPTKTIEVLQLQDQGSKMLLDSVLTTHERVVQISGLSATFAEIFLEIIQSSLPE
GVRLSVKEHTEEDFKGRFKARPELEELLAKLK

Sequence length

212

Interactions

View interactions

	Reactome
			Mitochondrial translation elongation Mitochondrial translation termination

Show/Hide Unknown Diseases (2)

Disease term	Disease name	References	Source
Unknown
Mental depression	Major Depressive Disorder	29317602	ClinVar
Mental Depression	Mental Depression		GWAS

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Adrenocortical Carcinoma	Associate	20231622
Carcinoma Hepatocellular	Stimulate	38093387
Colorectal Neoplasms	Associate	33048115
Colorectal Neoplasms	Stimulate	38093387
Osteosarcoma	Associate	38093387
Retinoblastoma	Associate	38093387

MRPL48 (mitochondrial ribosomal protein L48)