LSR (lipolysis stimulated lipoprotein receptor)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51599
Gene name Gene Name - the full gene name approved by the HGNC.
Lipolysis stimulated lipoprotein receptor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LSR
Synonyms (NCBI Gene) Gene synonyms aliases
ILDR3, LISCH7
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.12
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(7)
miRTarBase ID miRNA Experiments Reference
MIRT051509 hsa-let-7e-5p CLASH 23622248
MIRT1121971 hsa-miR-205 CLIP-seq
MIRT1121972 hsa-miR-3671 CLIP-seq
MIRT1121973 hsa-miR-4255 CLIP-seq
MIRT1121974 hsa-miR-4302 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(14)
GO ID Ontology Definition Evidence Reference
GO:0001889 Process Liver development ISS
GO:0005886 Component Plasma membrane ISS
GO:0016021 Component Integral component of membrane IEA
GO:0019216 Process Regulation of lipid metabolic process IEA
GO:0034361 Component Very-low-density lipoprotein particle IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
616582 29572 ENSG00000105699
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q86X29
Protein name Lipolysis-stimulated lipoprotein receptor (Angulin-1)
Protein function Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). Maintains epithelial barrier function b
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05624 LSR 259 → 306 Lipolysis stimulated receptor (LSR) Domain
Sequence 
MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG
RTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD
KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV
DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP
GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA
GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS
RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS
EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Sequence length 649
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Carcinoma Carcinoma, Carcinoma, Spindle-Cell, Undifferentiated carcinoma rs121912654, rs555607708, rs786202962, rs1564055259 16316942, 12376462
Show/Hide Text Mining Associations (20)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 36961882
Alzheimer Disease Associate 35347084
Breast Neoplasms Associate 24637461
Carcinogenesis Associate 24637461
Carcinoma Ductal Associate 24637461
Carcinoma Endometrioid Inhibit 35883247
Cytokine Release Syndrome Inhibit 33660567
Diabetes Mellitus Type 2 Stimulate 27036040
Endometrial Neoplasms Inhibit 27036040, 35883247
Endometrial Neoplasms Associate 28071680, 31782346