Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51573
Gene name Gene Name - the full gene name approved by the HGNC.
Glycerophosphodiester phosphodiesterase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GDE1
Synonyms (NCBI Gene) Gene synonyms aliases
363E6.2, MIR16
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p12.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005236 hsa-let-7b-5p pSILAC 18668040
MIRT025463 hsa-miR-34a-5p Sequencing 20371350
MIRT029380 hsa-miR-26b-5p Microarray 19088304
MIRT005236 hsa-let-7b-5p Proteomics;Other 18668040
MIRT048644 hsa-miR-99a-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004622 Function Lysophospholipase activity ISS
GO:0005515 Function Protein binding IPI 32296183
GO:0005886 Component Plasma membrane ISS
GO:0005886 Component Plasma membrane TAS
GO:0006580 Process Ethanolamine metabolic process ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
605943 29644 ENSG00000006007
Protein
UniProt ID Q9NZC3
Protein name Glycerophosphodiester phosphodiesterase 1 (Glycerophosphoinositol glycerophosphodiesterase GDE1) (EC 3.1.4.44) (Lysophospholipase D GDE1) (EC 3.1.4.-) (Membrane-interacting protein of RGS16) (RGS16-interacting membrane protein)
Protein function Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity). Hydrolyzes glycerophospho-N-acylethanol
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03009 GDPD 70 325 Glycerophosphoryl diester phosphodiesterase family Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10760272}.
Sequence
Sequence length 331
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Glycerophospholipid catabolism
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Mental depression Unipolar Depression, Major Depressive Disorder 25779937 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Abortion Spontaneous Associate 37373283
Adenocarcinoma of Lung Inhibit 19549910
Adenocarcinoma of Lung Associate 26061016
Adenoma Associate 29565480
Arthritis Rheumatoid Stimulate 18759964
Arthritis Rheumatoid Associate 20470394, 37506143
Arthritis Rheumatoid Inhibit 23897768
Asthma Associate 30942450
Atherosclerosis Stimulate 27846323
Atrial Fibrillation Associate 34100730