UFM1 (ubiquitin fold modifier 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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51569 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Ubiquitin fold modifier 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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UFM1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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BM-002, C13orf20, HLD14 |
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Chromosome
Chromosome number
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13 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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13q13.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al. |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P61960 | ||||||||||
| Protein name | Ubiquitin-fold modifier 1 | ||||||||||
| Protein function | Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847, PubMed:27653677, PubMed:29868776, PubMed:30626644 | ||||||||||
| PDB | 1WXS , 5HKH , 5IA7 , 5IA8 , 5IAA , 5L95 , 6H77 , 7W3N , 8BZR , 8OHD , 8OJ0 , 8OJ5 , 8QFC | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 85 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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