Gene Gene information from NCBI Gene database.
Entrez ID 51559
Gene name 5'-nucleotidase domain containing 3
Gene symbol NT5DC3
Synonyms (NCBI Gene)
TU12B1-TYTU12B1TY
Chromosome 12
Chromosome location 12q23.3
miRNA miRNA information provided by mirtarbase database.
1144
miRTarBase ID miRNA Experiments Reference
MIRT016515 hsa-miR-193b-3p Microarray 20304954
MIRT018478 hsa-miR-335-5p Microarray 18185580
MIRT049332 hsa-miR-92a-3p CLASH 23622248
MIRT047697 hsa-miR-10a-5p CLASH 23622248
MIRT043963 hsa-miR-378a-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005829 Component Cytosol IEA
GO:0008253 Function 5'-nucleotidase activity IBA
GO:0016787 Function Hydrolase activity IEA
GO:0043235 Component Receptor complex IDA 23382219
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611076 30826 ENSG00000111696
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86UY8
Protein name 5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05761 5_nucleotid 85 528 Family
Tissue specificity TISSUE SPECIFICITY: Expressed in brain, placenta, skeletal muscle, pancreas, testis, uterus, and small intestine. Reduced expression in pancreatic cancer cells. {ECO:0000269|PubMed:15547748}.
Sequence
Sequence length 548
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TREATMENT-RESISTANT HYPERTENSION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Breast Neoplasms Associate 36820551
★☆☆☆☆
Found in Text Mining only