PEX5L (peroxisomal biogenesis factor 5 like)

Gene

• Entrez ID: 51555
• Gene name: Peroxisomal biogenesis factor 5 like
• Gene symbol: PEX5L
• Synonyms (NCBI Gene): PEX5R, PEX5RP, PXR2, PXR2B, TRIP8b
• Chromosome: 3
• Chromosome location: 3q26.33

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT029375	hsa-miR-26b-5p	Microarray	19088304
MIRT389969	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521979	hsa-miR-138-1-3p	HITS-CLIP	21572407
MIRT521977	hsa-miR-3682-5p	HITS-CLIP	21572407
MIRT521978	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT521980	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT521980	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT389969	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521979	hsa-miR-138-1-3p	HITS-CLIP	23313552
MIRT521977	hsa-miR-3682-5p	HITS-CLIP	23313552
MIRT521978	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT655236	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT655235	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT655234	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT655233	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT655232	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT655231	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT655230	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT655229	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT655228	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT655227	hsa-miR-4284	HITS-CLIP	23824327
MIRT389969	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT521979	hsa-miR-138-1-3p	HITS-CLIP	23824327
MIRT521977	hsa-miR-3682-5p	HITS-CLIP	23824327
MIRT521978	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521980	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT389969	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT521979	hsa-miR-138-1-3p	PAR-CLIP	21572407
MIRT521977	hsa-miR-3682-5p	PAR-CLIP	21572407
MIRT521978	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT521980	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT535381	hsa-miR-326	PAR-CLIP	22012620
MIRT535380	hsa-miR-330-5p	PAR-CLIP	22012620
MIRT513769	hsa-miR-548n	PAR-CLIP	22012620
MIRT513768	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT513767	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT513766	hsa-miR-4282	PAR-CLIP	22012620
MIRT513765	hsa-miR-548at-5p	PAR-CLIP	22012620
MIRT513760	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT513764	hsa-miR-144-3p	PAR-CLIP	22012620
MIRT535379	hsa-miR-545-3p	PAR-CLIP	22012620
MIRT535378	hsa-miR-6892-3p	PAR-CLIP	22012620
MIRT535377	hsa-miR-2276-5p	PAR-CLIP	22012620
MIRT535376	hsa-miR-3183	PAR-CLIP	22012620
MIRT535375	hsa-miR-4723-3p	PAR-CLIP	22012620
MIRT535374	hsa-miR-6769b-3p	PAR-CLIP	22012620
MIRT513762	hsa-miR-139-5p	PAR-CLIP	22012620
MIRT535373	hsa-miR-4469	PAR-CLIP	22012620
MIRT535372	hsa-miR-6817-3p	PAR-CLIP	22012620
MIRT535371	hsa-miR-518c-5p	PAR-CLIP	22012620
MIRT535370	hsa-miR-6764-3p	PAR-CLIP	22012620
MIRT535369	hsa-miR-6824-3p	PAR-CLIP	22012620
MIRT535368	hsa-miR-875-3p	PAR-CLIP	22012620
MIRT535367	hsa-miR-6128	PAR-CLIP	22012620
MIRT513761	hsa-miR-548v	PAR-CLIP	22012620
MIRT535366	hsa-miR-7106-3p	PAR-CLIP	22012620
MIRT513760	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT535365	hsa-miR-642a-5p	PAR-CLIP	22012620
MIRT535364	hsa-miR-3191-5p	PAR-CLIP	22012620
MIRT535363	hsa-miR-1299	PAR-CLIP	22012620
MIRT521980	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT389969	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521979	hsa-miR-138-1-3p	PAR-CLIP	23446348
MIRT521977	hsa-miR-3682-5p	PAR-CLIP	23446348
MIRT521978	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT513769	hsa-miR-548n	PAR-CLIP	23446348
MIRT513768	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT513767	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT513766	hsa-miR-4282	PAR-CLIP	23446348
MIRT513765	hsa-miR-548at-5p	PAR-CLIP	23446348
MIRT513760	hsa-miR-101-3p	PAR-CLIP	23446348
MIRT513764	hsa-miR-144-3p	PAR-CLIP	23446348
MIRT513763	hsa-miR-545-5p	PAR-CLIP	23446348
MIRT513762	hsa-miR-139-5p	PAR-CLIP	23446348
MIRT513761	hsa-miR-548v	PAR-CLIP	23446348
MIRT513760	hsa-miR-101-3p	PAR-CLIP	23446348
MIRT513760	hsa-miR-101-3p	PAR-CLIP	27292025
MIRT513760	hsa-miR-101-3p	PAR-CLIP	27292025
MIRT513762	hsa-miR-139-5p	PAR-CLIP	27292025
MIRT513762	hsa-miR-139-5p	PAR-CLIP	27292025
MIRT513764	hsa-miR-144-3p	PAR-CLIP	27292025
MIRT513764	hsa-miR-144-3p	PAR-CLIP	27292025
MIRT513766	hsa-miR-4282	PAR-CLIP	27292025
MIRT513766	hsa-miR-4282	PAR-CLIP	27292025
MIRT513763	hsa-miR-545-5p	PAR-CLIP	27292025
MIRT513763	hsa-miR-545-5p	PAR-CLIP	27292025
MIRT513765	hsa-miR-548at-5p	PAR-CLIP	27292025
MIRT513765	hsa-miR-548at-5p	PAR-CLIP	27292025
MIRT513768	hsa-miR-548az-5p	PAR-CLIP	27292025
MIRT513768	hsa-miR-548az-5p	PAR-CLIP	27292025
MIRT513769	hsa-miR-548n	PAR-CLIP	27292025
MIRT513769	hsa-miR-548n	PAR-CLIP	27292025
MIRT513767	hsa-miR-548t-5p	PAR-CLIP	27292025
MIRT513767	hsa-miR-548t-5p	PAR-CLIP	27292025
MIRT513761	hsa-miR-548v	PAR-CLIP	27292025
MIRT513761	hsa-miR-548v	PAR-CLIP	27292025
MIRT389969	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521979	hsa-miR-138-1-3p	HITS-CLIP	21572407
MIRT521977	hsa-miR-3682-5p	HITS-CLIP	21572407
MIRT521978	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT521980	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT521980	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT389969	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521979	hsa-miR-138-1-3p	HITS-CLIP	23313552
MIRT521977	hsa-miR-3682-5p	HITS-CLIP	23313552
MIRT521978	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT655236	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT655235	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT655234	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT655233	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT655232	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT655231	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT655230	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT655229	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT655228	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT655227	hsa-miR-4284	HITS-CLIP	23824327
MIRT389969	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT521979	hsa-miR-138-1-3p	HITS-CLIP	23824327
MIRT521977	hsa-miR-3682-5p	HITS-CLIP	23824327
MIRT521978	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT521980	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT389969	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT521979	hsa-miR-138-1-3p	PAR-CLIP	21572407
MIRT521977	hsa-miR-3682-5p	PAR-CLIP	21572407
MIRT521978	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT521980	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT535381	hsa-miR-326	PAR-CLIP	22012620
MIRT535380	hsa-miR-330-5p	PAR-CLIP	22012620
MIRT513769	hsa-miR-548n	PAR-CLIP	22012620
MIRT513768	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT513767	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT513766	hsa-miR-4282	PAR-CLIP	22012620
MIRT513765	hsa-miR-548at-5p	PAR-CLIP	22012620
MIRT513760	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT513764	hsa-miR-144-3p	PAR-CLIP	22012620
MIRT535379	hsa-miR-545-3p	PAR-CLIP	22012620
MIRT535378	hsa-miR-6892-3p	PAR-CLIP	22012620
MIRT535377	hsa-miR-2276-5p	PAR-CLIP	22012620
MIRT535376	hsa-miR-3183	PAR-CLIP	22012620
MIRT535375	hsa-miR-4723-3p	PAR-CLIP	22012620
MIRT535374	hsa-miR-6769b-3p	PAR-CLIP	22012620
MIRT513762	hsa-miR-139-5p	PAR-CLIP	22012620
MIRT535373	hsa-miR-4469	PAR-CLIP	22012620
MIRT535372	hsa-miR-6817-3p	PAR-CLIP	22012620
MIRT535371	hsa-miR-518c-5p	PAR-CLIP	22012620
MIRT535370	hsa-miR-6764-3p	PAR-CLIP	22012620
MIRT535369	hsa-miR-6824-3p	PAR-CLIP	22012620
MIRT535368	hsa-miR-875-3p	PAR-CLIP	22012620
MIRT535367	hsa-miR-6128	PAR-CLIP	22012620
MIRT513761	hsa-miR-548v	PAR-CLIP	22012620
MIRT535366	hsa-miR-7106-3p	PAR-CLIP	22012620
MIRT513760	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT535365	hsa-miR-642a-5p	PAR-CLIP	22012620
MIRT535364	hsa-miR-3191-5p	PAR-CLIP	22012620
MIRT535363	hsa-miR-1299	PAR-CLIP	22012620
MIRT521980	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT389969	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521979	hsa-miR-138-1-3p	PAR-CLIP	23446348
MIRT521977	hsa-miR-3682-5p	PAR-CLIP	23446348
MIRT521978	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT513769	hsa-miR-548n	PAR-CLIP	23446348
MIRT513768	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT513767	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT513766	hsa-miR-4282	PAR-CLIP	23446348
MIRT513765	hsa-miR-548at-5p	PAR-CLIP	23446348
MIRT513760	hsa-miR-101-3p	PAR-CLIP	23446348
MIRT513764	hsa-miR-144-3p	PAR-CLIP	23446348
MIRT513763	hsa-miR-545-5p	PAR-CLIP	23446348
MIRT513762	hsa-miR-139-5p	PAR-CLIP	23446348
MIRT513761	hsa-miR-548v	PAR-CLIP	23446348
MIRT513760	hsa-miR-101-3p	PAR-CLIP	23446348
MIRT1226018	hsa-miR-1207-3p	CLIP-seq
MIRT1226019	hsa-miR-1245b-3p	CLIP-seq
MIRT1226020	hsa-miR-132	CLIP-seq
MIRT1226021	hsa-miR-148a	CLIP-seq
MIRT1226022	hsa-miR-148b	CLIP-seq
MIRT1226023	hsa-miR-152	CLIP-seq
MIRT1226024	hsa-miR-212	CLIP-seq
MIRT1226025	hsa-miR-3200-5p	CLIP-seq
MIRT1226026	hsa-miR-377	CLIP-seq
MIRT1226027	hsa-miR-4326	CLIP-seq
MIRT1226028	hsa-miR-4330	CLIP-seq
MIRT1226029	hsa-miR-4705	CLIP-seq
MIRT1226030	hsa-miR-4795-3p	CLIP-seq
MIRT1226031	hsa-miR-576-3p	CLIP-seq
MIRT1226032	hsa-miR-592	CLIP-seq
MIRT1226033	hsa-miR-597	CLIP-seq
MIRT1552243	hsa-miR-642a	CLIP-seq
MIRT1226018	hsa-miR-1207-3p	CLIP-seq
MIRT1226019	hsa-miR-1245b-3p	CLIP-seq
MIRT1920752	hsa-miR-2276	CLIP-seq
MIRT1226028	hsa-miR-4330	CLIP-seq
MIRT1920753	hsa-miR-4708-3p	CLIP-seq
MIRT1226031	hsa-miR-576-3p	CLIP-seq
MIRT1226032	hsa-miR-592	CLIP-seq
MIRT1226033	hsa-miR-597	CLIP-seq
MIRT1226018	hsa-miR-1207-3p	CLIP-seq
MIRT1226019	hsa-miR-1245b-3p	CLIP-seq
MIRT1920752	hsa-miR-2276	CLIP-seq
MIRT1226028	hsa-miR-4330	CLIP-seq
MIRT1920753	hsa-miR-4708-3p	CLIP-seq
MIRT1226031	hsa-miR-576-3p	CLIP-seq
MIRT1226032	hsa-miR-592	CLIP-seq
MIRT1226033	hsa-miR-597	CLIP-seq
MIRT1226018	hsa-miR-1207-3p	CLIP-seq
MIRT1226019	hsa-miR-1245b-3p	CLIP-seq
MIRT1920752	hsa-miR-2276	CLIP-seq
MIRT1226028	hsa-miR-4330	CLIP-seq
MIRT1920753	hsa-miR-4708-3p	CLIP-seq
MIRT1226031	hsa-miR-576-3p	CLIP-seq
MIRT1226032	hsa-miR-592	CLIP-seq
MIRT1226033	hsa-miR-597	CLIP-seq
MIRT2066037	hsa-miR-1256	CLIP-seq
MIRT2066038	hsa-miR-34b	CLIP-seq
MIRT1226026	hsa-miR-377	CLIP-seq
MIRT2066039	hsa-miR-4276	CLIP-seq
MIRT2066040	hsa-miR-431	CLIP-seq
MIRT2066041	hsa-miR-4720-5p	CLIP-seq
MIRT2066042	hsa-miR-4799-3p	CLIP-seq
MIRT2066043	hsa-miR-518a-5p	CLIP-seq
MIRT2066044	hsa-miR-527	CLIP-seq
MIRT2066045	hsa-miR-622	CLIP-seq
MIRT1552243	hsa-miR-642a	CLIP-seq
MIRT2293700	hsa-miR-1827	CLIP-seq
MIRT2293701	hsa-miR-2682	CLIP-seq
MIRT2293702	hsa-miR-300	CLIP-seq
MIRT2293703	hsa-miR-3140-3p	CLIP-seq
MIRT2293704	hsa-miR-338-5p	CLIP-seq
MIRT2293705	hsa-miR-34a	CLIP-seq
MIRT2293706	hsa-miR-34c-5p	CLIP-seq
MIRT2293707	hsa-miR-381	CLIP-seq
MIRT2293708	hsa-miR-448	CLIP-seq
MIRT2293709	hsa-miR-449a	CLIP-seq
MIRT2293710	hsa-miR-449b	CLIP-seq
MIRT2293711	hsa-miR-449c	CLIP-seq
MIRT2293712	hsa-miR-4649-3p	CLIP-seq
MIRT2293713	hsa-miR-4666-3p	CLIP-seq
MIRT2293714	hsa-miR-4704-5p	CLIP-seq
MIRT2293715	hsa-miR-520f	CLIP-seq
MIRT2293716	hsa-miR-548a-3p	CLIP-seq
MIRT2293717	hsa-miR-548ae	CLIP-seq
MIRT2293718	hsa-miR-548aj	CLIP-seq
MIRT2293719	hsa-miR-548am	CLIP-seq
MIRT2293720	hsa-miR-548e	CLIP-seq
MIRT2293721	hsa-miR-548f	CLIP-seq
MIRT2293722	hsa-miR-548g	CLIP-seq
MIRT2293723	hsa-miR-548x	CLIP-seq
MIRT2066037	hsa-miR-1256	CLIP-seq
MIRT2591727	hsa-miR-1323	CLIP-seq
MIRT2591728	hsa-miR-3065-5p	CLIP-seq
MIRT2591729	hsa-miR-338-3p	CLIP-seq
MIRT2591730	hsa-miR-4530	CLIP-seq
MIRT1920753	hsa-miR-4708-3p	CLIP-seq
MIRT2591731	hsa-miR-508-5p	CLIP-seq
MIRT2591732	hsa-miR-548o	CLIP-seq
MIRT2591733	hsa-miR-766	CLIP-seq
MIRT2591727	hsa-miR-1323	CLIP-seq
MIRT2591728	hsa-miR-3065-5p	CLIP-seq
MIRT2591729	hsa-miR-338-3p	CLIP-seq
MIRT2591730	hsa-miR-4530	CLIP-seq
MIRT1920753	hsa-miR-4708-3p	CLIP-seq
MIRT2591731	hsa-miR-508-5p	CLIP-seq
MIRT2591732	hsa-miR-548o	CLIP-seq
MIRT2591733	hsa-miR-766	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000268	Function	Peroxisome targeting sequence binding	IDA	18346465
GO:0005052	Function	Peroxisome matrix targeting signal-1 binding	IBA
GO:0005052	Function	Peroxisome matrix targeting signal-1 binding	IDA	11463335
GO:0005515	Function	Protein binding	IPI	25800552
GO:0005737	Component	Cytoplasm	IEA
GO:0005778	Component	Peroxisomal membrane	IBA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	11463335
GO:0016020	Component	Membrane	IEA
GO:0016560	Process	Protein import into peroxisome matrix, docking	IBA
GO:0031267	Function	Small GTPase binding	IPI	18346465
GO:0043235	Component	Receptor complex	IDA	23382219

Other IDs

• MIM: 611058
• HGNC: 30024
• e!Ensembl: ENSG00000114757

Protein

• UniProt ID: Q8IYB4
• Protein name: PEX5-related protein (PEX2-related protein) (PEX5-like protein) (Peroxin-5-related protein) (Peroxisome biogenesis factor 5-like) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b)
• Protein function: Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13181	TPR_8	360 → 393	Tetratricopeptide repeat	Repeat
  PF13432	TPR_16	487 → 540		Family
  PF13181	TPR_8	542 → 575	Tetratricopeptide repeat	Repeat

• Tissue specificity: TISSUE SPECIFICITY: Mainly expressed in brain. Also expressed in pancreas, testis and pituitary. {ECO:0000269|PubMed:11463335}.
• Sequence:

  MYQGHMQKSKEQGYGKLSSDEDLEIIVDQKQGKGSRAADKAVAMVMKEIPREESAEEKPL
  LTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIARPVTSNTAVLTTGLDLLDLSEPVSQ
  TQTKAKKSEPSSKTSSLKKKADGSDLISTDAEQRGQPLRVPETSSLDLDIQTQLEKWDDV
  KFHGDRNTKGHPMAERKSSSSRTGSKELLWSSEHRSQPELSGGKSALNSESASELELVAP
  TQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQ
  EAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDA
  EAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNW
  IKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGL
  GVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPG
  FIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSL
  MDQPELFQAANLGDLDVLLRAFNLDP

• Sequence length: 626

Pathways

KEGG:

Peroxisome