Gene Gene information from NCBI Gene database.
Entrez ID 51552
Gene name RAB14, member RAS oncogene family
Gene symbol RAB14
Synonyms (NCBI Gene)
FBPRAB-14
Chromosome 9
Chromosome location 9q33.2
Summary RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they
miRNA miRNA information provided by mirtarbase database.
883
miRTarBase ID miRNA Experiments Reference
MIRT006533 hsa-miR-451a FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot 21358675
MIRT006533 hsa-miR-451a FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot 21358675
MIRT006533 hsa-miR-451a FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot 21358675
MIRT006533 hsa-miR-451a FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot 21358675
MIRT006533 hsa-miR-451a Reporter assay 21358675
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
67
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000166 Function Nucleotide binding IEA
GO:0001845 Process Phagolysosome assembly IBA
GO:0003924 Function GTPase activity IBA
GO:0003924 Function GTPase activity IDA 16034420, 17562788, 20534812
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612673 16524 ENSG00000119396
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P61106
Protein name Ras-related protein Rab-14 (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r
PDB 1Z0F , 4D0G , 4DRZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 13 174 Ras family Domain
Sequence
Sequence length 215
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Efferocytosis
AMPK signaling pathway
  Synthesis of PIPs at the plasma membrane
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs