Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51552
Gene name Gene Name - the full gene name approved by the HGNC.
RAB14, member RAS oncogene family
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RAB14
Synonyms (NCBI Gene) Gene synonyms aliases
FBP, RAB-14
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q33.2
Summary Summary of gene provided in NCBI Entrez Gene.
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Flow, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 21358675
MIRT006533 hsa-miR-451a Reporter assay 21358675
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0003924 Function GTPase activity IBA 21873635
GO:0003924 Function GTPase activity IDA 16034420, 17562788
GO:0003924 Function GTPase activity NAS 15004230
GO:0005515 Function Protein binding IPI 16034420, 16237761, 16902405, 25416956, 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612673 16524 ENSG00000119396
Protein
UniProt ID P61106
Protein name Ras-related protein Rab-14 (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r
PDB 1Z0F , 4D0G , 4DRZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 13 174 Ras family Domain
Sequence
Sequence length 215
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Efferocytosis
AMPK signaling pathway
  Synthesis of PIPs at the plasma membrane
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Rheumatoid arthritis Rheumatoid Arthritis rs587776843 19503088
Unknown
Disease term Disease name Evidence References Source
Neurodevelopmental Disorders neurodevelopmental disorder GenCC
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 35181591
Allergic Fungal Sinusitis Stimulate 29270391
Colorectal Neoplasms Associate 31364111, 33344634
Coronary Restenosis Associate 35968900
COVID 19 Associate 35239653
Death Associate 35239653
Diabetes Mellitus Type 1 Associate 37576973
Hypoxia Associate 36785792
Myocardial Infarction Associate 36785792
Nasopharyngeal Carcinoma Associate 25201065