Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51550
Gene name Gene Name - the full gene name approved by the HGNC.	Cyclin dependent kinase 2 interacting protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CINP
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q32.31
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1060499740	A>C	Likely-pathogenic	Stop lost, terminator codon variant, 3 prime UTR variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629245	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629244	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629243	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629242	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629241	hsa-miR-3666	HITS-CLIP	23824327
MIRT629240	hsa-miR-4295	HITS-CLIP	23824327
MIRT629239	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629238	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629237	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629236	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629235	hsa-miR-4284	HITS-CLIP	23824327
MIRT629234	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT629233	hsa-miR-3652	HITS-CLIP	23824327
MIRT629232	hsa-miR-4430	HITS-CLIP	23824327
MIRT629231	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT1964898	hsa-miR-2682	CLIP-seq
MIRT1964899	hsa-miR-3120-5p	CLIP-seq
MIRT1964900	hsa-miR-346	CLIP-seq
MIRT1964901	hsa-miR-4288	CLIP-seq
MIRT1964902	hsa-miR-4494	CLIP-seq
MIRT1964903	hsa-miR-449c	CLIP-seq
MIRT1964904	hsa-miR-4771	CLIP-seq
MIRT1964905	hsa-miR-632	CLIP-seq
MIRT1964906	hsa-miR-940	CLIP-seq
MIRT2503724	hsa-miR-1343	CLIP-seq
MIRT1964898	hsa-miR-2682	CLIP-seq
MIRT2503725	hsa-miR-3176	CLIP-seq
MIRT1964900	hsa-miR-346	CLIP-seq
MIRT2503726	hsa-miR-3667-5p	CLIP-seq
MIRT2503727	hsa-miR-3922-3p	CLIP-seq
MIRT1964901	hsa-miR-4288	CLIP-seq
MIRT2503728	hsa-miR-4435	CLIP-seq
MIRT1964902	hsa-miR-4494	CLIP-seq
MIRT1964903	hsa-miR-449c	CLIP-seq
MIRT2503729	hsa-miR-4645-5p	CLIP-seq
MIRT2503730	hsa-miR-4650-5p	CLIP-seq
MIRT2503731	hsa-miR-4673	CLIP-seq
MIRT1964904	hsa-miR-4771	CLIP-seq
MIRT2503732	hsa-miR-615-5p	CLIP-seq
MIRT1964905	hsa-miR-632	CLIP-seq
MIRT2503733	hsa-miR-640	CLIP-seq
MIRT1964906	hsa-miR-940	CLIP-seq
MIRT2503724	hsa-miR-1343	CLIP-seq
MIRT2678207	hsa-miR-139-3p	CLIP-seq
MIRT2678208	hsa-miR-199a-5p	CLIP-seq
MIRT2678209	hsa-miR-199b-5p	CLIP-seq
MIRT2503725	hsa-miR-3176	CLIP-seq
MIRT2678210	hsa-miR-3190	CLIP-seq
MIRT2678211	hsa-miR-3202	CLIP-seq
MIRT2503726	hsa-miR-3667-5p	CLIP-seq
MIRT2503727	hsa-miR-3922-3p	CLIP-seq
MIRT2503728	hsa-miR-4435	CLIP-seq
MIRT2678212	hsa-miR-4533	CLIP-seq
MIRT2503729	hsa-miR-4645-5p	CLIP-seq
MIRT2503730	hsa-miR-4650-5p	CLIP-seq
MIRT2678213	hsa-miR-4669	CLIP-seq
MIRT2503731	hsa-miR-4673	CLIP-seq
MIRT2678214	hsa-miR-4676-5p	CLIP-seq
MIRT2678215	hsa-miR-575	CLIP-seq
MIRT2503732	hsa-miR-615-5p	CLIP-seq
MIRT2503733	hsa-miR-640	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 19889979, 21131973, 25416956, 28514442, 31515488, 32296183, 33961781, 35354024, 38554706
GO:0005634	Component	Nucleus	IEA
GO:0006260	Process	DNA replication	IEA
GO:0006281	Process	DNA repair	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042273	Process	Ribosomal large subunit biogenesis	IDA	35354024
GO:0051301	Process	Cell division	IEA
GO:1990275	Function	Preribosome binding	IDA	35354024

MIM	HGNC	e!Ensembl
613362	23789	ENSG00000100865

Protein

UniProt ID

Q9BW66

Protein name

Cyclin-dependent kinase 2-interacting protein (CDK2-interacting protein)

Protein function

Component of the DNA replication complex, which interacts with two kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication (PubMed:16082200, PubMed:19889979). Reg

PDB

8CIH , 8RHN

Family and domains

Sequence

MEAKTLGTVTPRKPVLSVSARKIKDNAADWHNLILKWETLNDAGFTTANNIANLKISLLN
KDKIELDSSSPASKENEEKVCLEYNEELEKLCEELQATLDGLTKIQVKMEKLSSTTKGIC
ELENYHYGEESKRPPLFHTWPTTHFYEVSHKLLEMYRKELLLKRTVAKELAHTGDPDLTL
SYLSMWLHQPYVESDSRLHLESMLLETGHRAL

Sequence length

212

Interactions

View interactions

CINP (cyclin dependent kinase 2 interacting protein)