NCKIPSD (NCK interacting protein with SH3 domain)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51517 |
| Gene name | NCK interacting protein with SH3 domain |
| Gene symbol | NCKIPSD |
| Synonyms (NCBI Gene) |
AF3P21DIPDIP1ORF1SPIN90VIP54WASLBPWISH
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| Chromosome | 3 |
| Chromosome location | 3p21.31 |
| Summary | The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress |
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miRNA
miRNA information provided by mirtarbase database.
554
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NZQ3 | |||||||||||||||
| Protein name | NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 ad | |||||||||||||||
| Protein function | Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 ( | |||||||||||||||
| PDB | 6DEC , 6DED , 6DEE | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen. {ECO:0000269|PubMed:10619843}. | |||||||||||||||
| Sequence |
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| Sequence length | 722 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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