Gene Gene information from NCBI Gene database.
Entrez ID 51491
Gene name NOP16 nucleolar protein
Gene symbol NOP16
Synonyms (NCBI Gene)
HSPC111HSPC185
Chromosome 5
Chromosome location 5q35.2
Summary This gene encodes a protein that is localized to the nucleolus. Expression of this gene is induced by estrogens and Myc protein and is a marker of poor patient survival in breast cancer. Alternative splicing results in multiple transcript variants. [provi
miRNA miRNA information provided by mirtarbase database.
2
miRTarBase ID miRNA Experiments Reference
MIRT021296 hsa-miR-125a-5p Sequencing 20371350
MIRT025600 hsa-miR-10a-5p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
GO:0005730 Component Nucleolus IBA
GO:0005730 Component Nucleolus IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612861 26934 ENSG00000048162
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y3C1
Protein name Nucleolar protein 16 (HBV pre-S2 trans-regulated protein 3)
PDB 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09420 Nop16 7 87 Ribosome biogenesis protein Nop16 Family
PF09420 Nop16 65 156 Ribosome biogenesis protein Nop16 Family
Sequence
MPKAKGKTRRQKFGYSVNRKRLNRNARRKAAPRIECSHIRHAWDHAKSVRQNLAEMGLAV
DPNR
AVPLRKRKVKAMEVDIEERPKELVRKPYVLNDLEAEASLPEKKGNTLSRDLIDYVR
YMVENHGEDYKAMARDEKNYYQDTPKQIRSKINVYK
RFYPAEWQDFLDSLQKRKMEVE
Sequence length 178
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Ovarian serous cystadenocarcinoma Uncertain significance rs201464061 RCV005932480
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 18373870
Carcinoma Hepatocellular Associate 38251077
Neoplasms Associate 38251077