Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51474
Gene name Gene Name - the full gene name approved by the HGNC.	LIM domain and actin binding 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LIMA1
Synonyms (NCBI Gene) Gene synonyms aliases	EPLIN, LDLCQ8, SREBP3
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q13.12
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms ha

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020165	hsa-miR-130b-3p	Sequencing	20371350
MIRT027946	hsa-miR-93-5p	Sequencing	20371350
MIRT028234	hsa-miR-33a-5p	Sequencing	20371350
MIRT028688	hsa-miR-27a-3p	Sequencing	20371350
MIRT051156	hsa-miR-16-5p	CLASH	23622248
MIRT047864	hsa-miR-30c-5p	CLASH	23622248
MIRT047524	hsa-miR-10a-5p	CLASH	23622248
MIRT044924	hsa-miR-186-5p	CLASH	23622248
MIRT044040	hsa-miR-365a-3p	CLASH	23622248
MIRT042791	hsa-miR-339-5p	CLASH	23622248
MIRT037112	hsa-miR-877-3p	CLASH	23622248
MIRT536313	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT536312	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT536311	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT536310	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT027946	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT440326	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT536309	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT440325	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT573376	hsa-miR-3609	PAR-CLIP	20371350
MIRT573377	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT573375	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT573374	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT573373	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT573372	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT474152	hsa-miR-3120-3p	PAR-CLIP	20371350
MIRT474151	hsa-miR-451b	PAR-CLIP	20371350
MIRT187058	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT474150	hsa-miR-3074-3p	PAR-CLIP	20371350
MIRT187051	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT474146	hsa-miR-499a-3p	PAR-CLIP	20371350
MIRT562787	hsa-miR-6768-3p	PAR-CLIP	20371350
MIRT562786	hsa-miR-4715-5p	PAR-CLIP	20371350
MIRT562785	hsa-miR-4259	PAR-CLIP	20371350
MIRT562784	hsa-miR-6865-3p	PAR-CLIP	20371350
MIRT562783	hsa-miR-3620-3p	PAR-CLIP	20371350
MIRT562782	hsa-miR-6814-5p	PAR-CLIP	20371350
MIRT562781	hsa-miR-299-5p	PAR-CLIP	20371350
MIRT187029	hsa-miR-4775	PAR-CLIP	20371350
MIRT562780	hsa-miR-6802-3p	PAR-CLIP	20371350
MIRT562779	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT562778	hsa-miR-5096	PAR-CLIP	20371350
MIRT474152	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT474151	hsa-miR-451b	PAR-CLIP	21572407
MIRT187058	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT474150	hsa-miR-3074-3p	PAR-CLIP	21572407
MIRT474149	hsa-miR-6072	PAR-CLIP	21572407
MIRT474148	hsa-miR-6891-3p	PAR-CLIP	21572407
MIRT187051	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT474147	hsa-miR-670-3p	PAR-CLIP	21572407
MIRT474146	hsa-miR-499a-3p	PAR-CLIP	21572407
MIRT536313	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT536312	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT536311	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT536310	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT027946	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT440326	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT536309	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT440325	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT536308	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT536307	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT536306	hsa-miR-302a-3p	PAR-CLIP	22012620
MIRT536305	hsa-miR-302b-3p	PAR-CLIP	22012620
MIRT536304	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT536303	hsa-miR-302d-3p	PAR-CLIP	22012620
MIRT536302	hsa-miR-302e	PAR-CLIP	22012620
MIRT536301	hsa-miR-372-3p	PAR-CLIP	22012620
MIRT536300	hsa-miR-373-3p	PAR-CLIP	22012620
MIRT536299	hsa-miR-520a-3p	PAR-CLIP	22012620
MIRT536298	hsa-miR-520b	PAR-CLIP	22012620
MIRT536297	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT536296	hsa-miR-520d-3p	PAR-CLIP	22012620
MIRT536295	hsa-miR-520e	PAR-CLIP	22012620
MIRT232297	hsa-miR-875-5p	PAR-CLIP	22012620
MIRT536294	hsa-miR-3613-3p	PAR-CLIP	22012620
MIRT536293	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT536292	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT536291	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT536290	hsa-miR-1267	PAR-CLIP	22012620
MIRT536289	hsa-miR-367-5p	PAR-CLIP	22012620
MIRT536288	hsa-miR-3194-3p	PAR-CLIP	22012620
MIRT536287	hsa-miR-496	PAR-CLIP	22012620
MIRT536286	hsa-miR-3613-5p	PAR-CLIP	22012620
MIRT536285	hsa-miR-4777-3p	PAR-CLIP	22012620
MIRT536284	hsa-miR-3144-3p	PAR-CLIP	22012620
MIRT536283	hsa-miR-6836-3p	PAR-CLIP	22012620
MIRT536282	hsa-miR-5691	PAR-CLIP	22012620
MIRT536281	hsa-miR-6805-3p	PAR-CLIP	22012620
MIRT536280	hsa-miR-3152-5p	PAR-CLIP	22012620
MIRT474152	hsa-miR-3120-3p	PAR-CLIP	23592263
MIRT474151	hsa-miR-451b	PAR-CLIP	23592263
MIRT187058	hsa-miR-5011-5p	PAR-CLIP	23592263
MIRT474150	hsa-miR-3074-3p	PAR-CLIP	23592263
MIRT474149	hsa-miR-6072	PAR-CLIP	23592263
MIRT474148	hsa-miR-6891-3p	PAR-CLIP	23592263
MIRT187051	hsa-miR-190a-3p	PAR-CLIP	23592263
MIRT474147	hsa-miR-670-3p	PAR-CLIP	23592263
MIRT474146	hsa-miR-499a-3p	PAR-CLIP	23592263
MIRT440326	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440325	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440326	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT536313	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT536312	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT027946	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT536311	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440325	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT536313	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT536312	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT536311	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT536310	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT027946	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT440326	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT536309	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT440325	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT573376	hsa-miR-3609	PAR-CLIP	20371350
MIRT573377	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT573375	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT573374	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT573373	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT573372	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT474152	hsa-miR-3120-3p	PAR-CLIP	20371350
MIRT474151	hsa-miR-451b	PAR-CLIP	20371350
MIRT187058	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT474150	hsa-miR-3074-3p	PAR-CLIP	20371350
MIRT187051	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT474146	hsa-miR-499a-3p	PAR-CLIP	20371350
MIRT562787	hsa-miR-6768-3p	PAR-CLIP	20371350
MIRT562786	hsa-miR-4715-5p	PAR-CLIP	20371350
MIRT562785	hsa-miR-4259	PAR-CLIP	20371350
MIRT562784	hsa-miR-6865-3p	PAR-CLIP	20371350
MIRT562783	hsa-miR-3620-3p	PAR-CLIP	20371350
MIRT562782	hsa-miR-6814-5p	PAR-CLIP	20371350
MIRT562781	hsa-miR-299-5p	PAR-CLIP	20371350
MIRT187029	hsa-miR-4775	PAR-CLIP	20371350
MIRT562780	hsa-miR-6802-3p	PAR-CLIP	20371350
MIRT562779	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT562778	hsa-miR-5096	PAR-CLIP	20371350
MIRT474152	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT474151	hsa-miR-451b	PAR-CLIP	21572407
MIRT187058	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT474150	hsa-miR-3074-3p	PAR-CLIP	21572407
MIRT474149	hsa-miR-6072	PAR-CLIP	21572407
MIRT474148	hsa-miR-6891-3p	PAR-CLIP	21572407
MIRT187051	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT474147	hsa-miR-670-3p	PAR-CLIP	21572407
MIRT474146	hsa-miR-499a-3p	PAR-CLIP	21572407
MIRT536313	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT536312	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT536311	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT536310	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT027946	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT440326	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT536309	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT440325	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT536308	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT536307	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT536306	hsa-miR-302a-3p	PAR-CLIP	22012620
MIRT536305	hsa-miR-302b-3p	PAR-CLIP	22012620
MIRT536304	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT536303	hsa-miR-302d-3p	PAR-CLIP	22012620
MIRT536302	hsa-miR-302e	PAR-CLIP	22012620
MIRT536301	hsa-miR-372-3p	PAR-CLIP	22012620
MIRT536300	hsa-miR-373-3p	PAR-CLIP	22012620
MIRT536299	hsa-miR-520a-3p	PAR-CLIP	22012620
MIRT536298	hsa-miR-520b	PAR-CLIP	22012620
MIRT536297	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT536296	hsa-miR-520d-3p	PAR-CLIP	22012620
MIRT536295	hsa-miR-520e	PAR-CLIP	22012620
MIRT232297	hsa-miR-875-5p	PAR-CLIP	22012620
MIRT536294	hsa-miR-3613-3p	PAR-CLIP	22012620
MIRT536293	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT536292	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT536291	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT536290	hsa-miR-1267	PAR-CLIP	22012620
MIRT536289	hsa-miR-367-5p	PAR-CLIP	22012620
MIRT536288	hsa-miR-3194-3p	PAR-CLIP	22012620
MIRT536287	hsa-miR-496	PAR-CLIP	22012620
MIRT536286	hsa-miR-3613-5p	PAR-CLIP	22012620
MIRT536285	hsa-miR-4777-3p	PAR-CLIP	22012620
MIRT536284	hsa-miR-3144-3p	PAR-CLIP	22012620
MIRT536283	hsa-miR-6836-3p	PAR-CLIP	22012620
MIRT536282	hsa-miR-5691	PAR-CLIP	22012620
MIRT536281	hsa-miR-6805-3p	PAR-CLIP	22012620
MIRT536280	hsa-miR-3152-5p	PAR-CLIP	22012620
MIRT474152	hsa-miR-3120-3p	PAR-CLIP	23592263
MIRT474151	hsa-miR-451b	PAR-CLIP	23592263
MIRT187058	hsa-miR-5011-5p	PAR-CLIP	23592263
MIRT474150	hsa-miR-3074-3p	PAR-CLIP	23592263
MIRT474149	hsa-miR-6072	PAR-CLIP	23592263
MIRT474148	hsa-miR-6891-3p	PAR-CLIP	23592263
MIRT187051	hsa-miR-190a-3p	PAR-CLIP	23592263
MIRT474147	hsa-miR-670-3p	PAR-CLIP	23592263
MIRT474146	hsa-miR-499a-3p	PAR-CLIP	23592263
MIRT1109407	hsa-miR-21	CLIP-seq
MIRT1109408	hsa-miR-3122	CLIP-seq
MIRT1109409	hsa-miR-3689a-3p	CLIP-seq
MIRT1109410	hsa-miR-3689c	CLIP-seq
MIRT1109411	hsa-miR-3913-5p	CLIP-seq
MIRT1109412	hsa-miR-590-5p	CLIP-seq
MIRT1109413	hsa-miR-922	CLIP-seq
MIRT2030427	hsa-miR-1303	CLIP-seq
MIRT2030428	hsa-miR-3682-5p	CLIP-seq
MIRT2261132	hsa-miR-101	CLIP-seq
MIRT2261133	hsa-miR-106a	CLIP-seq
MIRT2261134	hsa-miR-106b	CLIP-seq
MIRT2261135	hsa-miR-1245	CLIP-seq
MIRT2261136	hsa-miR-1253	CLIP-seq
MIRT2261137	hsa-miR-1265	CLIP-seq
MIRT2261138	hsa-miR-1275	CLIP-seq
MIRT2030427	hsa-miR-1303	CLIP-seq
MIRT2261139	hsa-miR-141	CLIP-seq
MIRT2261140	hsa-miR-144	CLIP-seq
MIRT2261141	hsa-miR-17	CLIP-seq
MIRT2261142	hsa-miR-200a	CLIP-seq
MIRT2261143	hsa-miR-20a	CLIP-seq
MIRT2261144	hsa-miR-20b	CLIP-seq
MIRT1109407	hsa-miR-21	CLIP-seq
MIRT2261145	hsa-miR-23a	CLIP-seq
MIRT2261146	hsa-miR-23b	CLIP-seq
MIRT2261147	hsa-miR-23c	CLIP-seq
MIRT2261148	hsa-miR-297	CLIP-seq
MIRT1109408	hsa-miR-3122	CLIP-seq
MIRT2261149	hsa-miR-3198	CLIP-seq
MIRT2261150	hsa-miR-34a	CLIP-seq
MIRT2261151	hsa-miR-34c-5p	CLIP-seq
MIRT2261152	hsa-miR-3664-3p	CLIP-seq
MIRT1109409	hsa-miR-3689a-3p	CLIP-seq
MIRT1109410	hsa-miR-3689c	CLIP-seq
MIRT2261153	hsa-miR-3691-3p	CLIP-seq
MIRT1109411	hsa-miR-3913-5p	CLIP-seq
MIRT2261154	hsa-miR-4280	CLIP-seq
MIRT2261155	hsa-miR-4309	CLIP-seq
MIRT2261156	hsa-miR-4420	CLIP-seq
MIRT2261157	hsa-miR-4426	CLIP-seq
MIRT2261158	hsa-miR-4436a	CLIP-seq
MIRT2261159	hsa-miR-4436b-3p	CLIP-seq
MIRT2261160	hsa-miR-4444	CLIP-seq
MIRT2261161	hsa-miR-4477b	CLIP-seq
MIRT2261162	hsa-miR-449a	CLIP-seq
MIRT2261163	hsa-miR-449b	CLIP-seq
MIRT2261164	hsa-miR-4525	CLIP-seq
MIRT2261165	hsa-miR-455-5p	CLIP-seq
MIRT2261166	hsa-miR-4647	CLIP-seq
MIRT2261167	hsa-miR-4662b	CLIP-seq
MIRT2261168	hsa-miR-4665-5p	CLIP-seq
MIRT2261169	hsa-miR-4671-5p	CLIP-seq
MIRT2261170	hsa-miR-4678	CLIP-seq
MIRT2261171	hsa-miR-4703-3p	CLIP-seq
MIRT2261172	hsa-miR-4711-5p	CLIP-seq
MIRT2261173	hsa-miR-4723-5p	CLIP-seq
MIRT2261174	hsa-miR-4731-5p	CLIP-seq
MIRT2261175	hsa-miR-4742-3p	CLIP-seq
MIRT2261176	hsa-miR-4753-5p	CLIP-seq
MIRT2261177	hsa-miR-514	CLIP-seq
MIRT2261178	hsa-miR-514b-3p	CLIP-seq
MIRT2261179	hsa-miR-519d	CLIP-seq
MIRT2261180	hsa-miR-567	CLIP-seq
MIRT2261181	hsa-miR-579	CLIP-seq
MIRT1109412	hsa-miR-590-5p	CLIP-seq
MIRT2261182	hsa-miR-625	CLIP-seq
MIRT1109413	hsa-miR-922	CLIP-seq
MIRT2261183	hsa-miR-93	CLIP-seq
MIRT2261154	hsa-miR-4280	CLIP-seq
MIRT2261133	hsa-miR-106a	CLIP-seq
MIRT2261134	hsa-miR-106b	CLIP-seq
MIRT2261141	hsa-miR-17	CLIP-seq
MIRT2261143	hsa-miR-20a	CLIP-seq
MIRT2261144	hsa-miR-20b	CLIP-seq
MIRT2261179	hsa-miR-519d	CLIP-seq
MIRT2261183	hsa-miR-93	CLIP-seq
MIRT2261132	hsa-miR-101	CLIP-seq
MIRT2561113	hsa-miR-1226	CLIP-seq
MIRT2261135	hsa-miR-1245	CLIP-seq
MIRT2561114	hsa-miR-1251	CLIP-seq
MIRT2561115	hsa-miR-1252	CLIP-seq
MIRT2261136	hsa-miR-1253	CLIP-seq
MIRT2261138	hsa-miR-1275	CLIP-seq
MIRT2561116	hsa-miR-129-5p	CLIP-seq
MIRT2561117	hsa-miR-1301	CLIP-seq
MIRT2261139	hsa-miR-141	CLIP-seq
MIRT2261140	hsa-miR-144	CLIP-seq
MIRT2261142	hsa-miR-200a	CLIP-seq
MIRT2561118	hsa-miR-2052	CLIP-seq
MIRT2561119	hsa-miR-2113	CLIP-seq
MIRT2561120	hsa-miR-25	CLIP-seq
MIRT2561121	hsa-miR-3185	CLIP-seq
MIRT2261149	hsa-miR-3198	CLIP-seq
MIRT2561122	hsa-miR-32	CLIP-seq
MIRT2561123	hsa-miR-325	CLIP-seq
MIRT2561124	hsa-miR-338-3p	CLIP-seq
MIRT2561125	hsa-miR-363	CLIP-seq
MIRT2561126	hsa-miR-3646	CLIP-seq
MIRT2561127	hsa-miR-3653	CLIP-seq
MIRT2561128	hsa-miR-3658	CLIP-seq
MIRT2561129	hsa-miR-3662	CLIP-seq
MIRT2561130	hsa-miR-367	CLIP-seq
MIRT2561131	hsa-miR-3675-3p	CLIP-seq
MIRT2261155	hsa-miR-4309	CLIP-seq
MIRT2561132	hsa-miR-4317	CLIP-seq
MIRT2261157	hsa-miR-4426	CLIP-seq
MIRT2261161	hsa-miR-4477b	CLIP-seq
MIRT2561133	hsa-miR-448	CLIP-seq
MIRT2261164	hsa-miR-4525	CLIP-seq
MIRT2261166	hsa-miR-4647	CLIP-seq
MIRT2561134	hsa-miR-4660	CLIP-seq
MIRT2261167	hsa-miR-4662b	CLIP-seq
MIRT2261168	hsa-miR-4665-5p	CLIP-seq
MIRT2261170	hsa-miR-4678	CLIP-seq
MIRT2561135	hsa-miR-4712-3p	CLIP-seq
MIRT2261173	hsa-miR-4723-5p	CLIP-seq
MIRT2561136	hsa-miR-4733-3p	CLIP-seq
MIRT2261176	hsa-miR-4753-5p	CLIP-seq
MIRT2561137	hsa-miR-491-3p	CLIP-seq
MIRT2561138	hsa-miR-5047	CLIP-seq
MIRT2561139	hsa-miR-561	CLIP-seq
MIRT2261181	hsa-miR-579	CLIP-seq
MIRT2561140	hsa-miR-586	CLIP-seq
MIRT2561141	hsa-miR-599	CLIP-seq
MIRT2261182	hsa-miR-625	CLIP-seq
MIRT2561142	hsa-miR-628-3p	CLIP-seq
MIRT2561143	hsa-miR-92a	CLIP-seq
MIRT2561144	hsa-miR-92b	CLIP-seq
MIRT2561145	hsa-miR-944	CLIP-seq
MIRT2561113	hsa-miR-1226	CLIP-seq
MIRT2261135	hsa-miR-1245	CLIP-seq
MIRT2561114	hsa-miR-1251	CLIP-seq
MIRT2561115	hsa-miR-1252	CLIP-seq
MIRT2261136	hsa-miR-1253	CLIP-seq
MIRT2261138	hsa-miR-1275	CLIP-seq
MIRT2561116	hsa-miR-129-5p	CLIP-seq
MIRT2561117	hsa-miR-1301	CLIP-seq
MIRT2261139	hsa-miR-141	CLIP-seq
MIRT2261142	hsa-miR-200a	CLIP-seq
MIRT2561118	hsa-miR-2052	CLIP-seq
MIRT2561119	hsa-miR-2113	CLIP-seq
MIRT2561120	hsa-miR-25	CLIP-seq
MIRT2561121	hsa-miR-3185	CLIP-seq
MIRT2261149	hsa-miR-3198	CLIP-seq
MIRT2561122	hsa-miR-32	CLIP-seq
MIRT2561123	hsa-miR-325	CLIP-seq
MIRT2561124	hsa-miR-338-3p	CLIP-seq
MIRT2561125	hsa-miR-363	CLIP-seq
MIRT2561126	hsa-miR-3646	CLIP-seq
MIRT2561127	hsa-miR-3653	CLIP-seq
MIRT2561128	hsa-miR-3658	CLIP-seq
MIRT2561129	hsa-miR-3662	CLIP-seq
MIRT2561130	hsa-miR-367	CLIP-seq
MIRT2561131	hsa-miR-3675-3p	CLIP-seq
MIRT2261155	hsa-miR-4309	CLIP-seq
MIRT2561132	hsa-miR-4317	CLIP-seq
MIRT2261157	hsa-miR-4426	CLIP-seq
MIRT2261161	hsa-miR-4477b	CLIP-seq
MIRT2561133	hsa-miR-448	CLIP-seq
MIRT2261164	hsa-miR-4525	CLIP-seq
MIRT2261166	hsa-miR-4647	CLIP-seq
MIRT2561134	hsa-miR-4660	CLIP-seq
MIRT2261167	hsa-miR-4662b	CLIP-seq
MIRT2261168	hsa-miR-4665-5p	CLIP-seq
MIRT2261170	hsa-miR-4678	CLIP-seq
MIRT2561135	hsa-miR-4712-3p	CLIP-seq
MIRT2261173	hsa-miR-4723-5p	CLIP-seq
MIRT2561136	hsa-miR-4733-3p	CLIP-seq
MIRT2261176	hsa-miR-4753-5p	CLIP-seq
MIRT2561137	hsa-miR-491-3p	CLIP-seq
MIRT2561138	hsa-miR-5047	CLIP-seq
MIRT2561139	hsa-miR-561	CLIP-seq
MIRT2261181	hsa-miR-579	CLIP-seq
MIRT2561140	hsa-miR-586	CLIP-seq
MIRT2561141	hsa-miR-599	CLIP-seq
MIRT2261182	hsa-miR-625	CLIP-seq
MIRT2561142	hsa-miR-628-3p	CLIP-seq
MIRT2561143	hsa-miR-92a	CLIP-seq
MIRT2561144	hsa-miR-92b	CLIP-seq
MIRT2561145	hsa-miR-944	CLIP-seq

Show/Hide all(55)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001725	Component	Stress fiber	IDA	10618726
GO:0001725	Component	Stress fiber	IEA
GO:0001726	Component	Ruffle	IDA	32496561, 33999101
GO:0001726	Component	Ruffle	IEA
GO:0001726	Component	Ruffle	ISS
GO:0003779	Function	Actin binding	IEA
GO:0003785	Function	Actin monomer binding	IDA	12566430
GO:0005515	Function	Protein binding	IPI	15161933, 18093941, 20309963, 24694988, 29513927, 29880681, 32496561, 32707033, 36931259
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005884	Component	Actin filament	IDA	32496561
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005903	Component	Brush border	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IDA	10618726, 24694988
GO:0005925	Component	Focal adhesion	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0015629	Component	Actin cytoskeleton	IBA
GO:0015629	Component	Actin cytoskeleton	IDA
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IEA
GO:0016477	Process	Cell migration	ISS
GO:0030027	Component	Lamellipodium	IDA	33999101
GO:0030027	Component	Lamellipodium	IEA
GO:0030299	Process	Intestinal cholesterol absorption	IEA
GO:0030299	Process	Intestinal cholesterol absorption	ISS
GO:0030336	Process	Negative regulation of cell migration	IDA	33999101
GO:0030835	Process	Negative regulation of actin filament depolymerization	IDA	12566430
GO:0031526	Component	Brush border membrane	IEA
GO:0031526	Component	Brush border membrane	ISS
GO:0031529	Process	Ruffle organization	IDA	12566430
GO:0031529	Process	Ruffle organization	IEA
GO:0032154	Component	Cleavage furrow	IDA	20309963
GO:0032233	Process	Positive regulation of actin filament bundle assembly	IDA	33999101
GO:0042632	Process	Cholesterol homeostasis	IEA
GO:0042632	Process	Cholesterol homeostasis	ISS
GO:0042995	Component	Cell projection	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0046872	Function	Metal ion binding	IEA
GO:0051015	Function	Actin filament binding	IBA
GO:0051015	Function	Actin filament binding	IDA	12566430
GO:0051015	Function	Actin filament binding	IEA
GO:0051017	Process	Actin filament bundle assembly	IBA
GO:0051017	Process	Actin filament bundle assembly	IDA	12566430, 33999101
GO:0070161	Component	Anchoring junction	IEA
GO:0140778	Function	Microtubule stabilizing activity	IDA	33999101
GO:1902018	Process	Negative regulation of cilium assembly	IMP	32496561
GO:1902743	Process	Regulation of lamellipodium organization	IDA	33999101
GO:1902743	Process	Regulation of lamellipodium organization	IMP	33999101

MIM	HGNC	e!Ensembl
608364	24636	ENSG00000050405

Protein

UniProt ID

Q9UHB6

Protein name

LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)

Protein function

Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament

PDB

2D8Y

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00412	LIM	390 → 446	LIM domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in placenta, kidney, pancreas, prostate, ovary, spleen and heart. Also detected in lung, liver, brain, skeletal muscle, thymus, testis and intestine. Not detected in leukocytes. Isoform Beta expressed generally at very

Sequence

MESSPFNRRQWTSLSLRVTAKELSLVNKNKSSAIVEIFSKYQKAAEETNMEKKRSNTENL
SQHFRKGTLTVLKKKWENPGLGAESHTDSLRNSSTEIRHRADHPPAEVTSHAASGAKADQ
EEQIHPRSRLRSPPEALVQGRYPHIKDGEDLKDHSTESKKMENCLGESRHEVEKSEISEN
TDASGKIEKYNVPLNRLKMMFEKGEPTQTKILRAQSRSASGRKISENSYSLDDLEIGPGQ
LSSSTFDSEKNESRRNLELPRLSETSIKDRMAKYQAAVSKQSSSTNYTNELKASGGEIKI
HKMEQKENVPPGPEVCITHQEGEKISANENSLAVRSTPAEDDSRDSQVKSEVQQPVHPKP
LSPDSRASSLSESSPPKAMKKFQAPARETCVECQKTVYPMERLLANQQVFHISCFRCSYC
NNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGFGHRPHKDLWASKNENEEILERPAQ
LANARETPHSPGVEDAPIAKVGVLAASMEAKASSQQEKEDKPAETKKLRIAWPPPTELGS
SGSALEEGIKMSKPKWPPEDEISKPEVPEDVDLDLKKLRRSSSLKERSRPFTVAASFQST
SVKSPKTVSPPIRKGWSMSEQSEESVGGRVAERKQVENAKASKKNGNVGKTTWQNKESKG
ETGKRSKEGHSLEMENENLVENGADSDEDDNSFLKQQSPQEPKSLNWSSFVDNTFAEEFT
TQNQKSQDVELWEGEVVKELSVEEQIKRNRYYDEDEDEE

Sequence length

759

Interactions

View interactions

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Fibromuscular Dysplasia	Fibromuscular dysplasia	N/A	N/A	GWAS
Hypertension	Hypertension (confirmatory factor analysis Factor 12), High blood pressure / hypertension	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Acute Kidney Injury	Associate	37396184
Breast Neoplasms	Inhibit	21625216
Carcinoma Adenoid Cystic	Inhibit	18332873
Carcinoma Squamous Cell	Associate	32991423
Cholangiocarcinoma	Associate	32116234
Colorectal Neoplasms	Inhibit	21625216, 28465438, 36499558
Diabetic Nephropathies	Associate	37396184
Disease Resistance	Associate	36499558
Granulosa cell tumor of the ovary	Associate	25884336
Leukemia Myeloid Acute	Associate	36246561
Lymphatic Metastasis	Inhibit	21625216
Lymphoma B Cell Marginal Zone	Associate	25569716
Neoplasm Metastasis	Associate	21625216
Neoplasm Metastasis	Inhibit	23188829, 36497115
Neoplasms	Associate	12566430, 25884336, 36497115, 40269880
Neoplasms	Inhibit	18332873, 25569716, 28465438, 33917939, 36499558
Oncogene Addiction	Stimulate	36494469
Periodontal Diseases	Associate	39830509
Pituitary Neoplasms	Associate	26753958
Prostatic Neoplasms	Associate	21625216
Squamous Cell Carcinoma of Head and Neck	Inhibit	21625216
Stomach Neoplasms	Associate	33917939
Urinary Bladder Neoplasms	Inhibit	40269880

LIMA1 (LIM domain and actin binding 1)