Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51466
Gene name Gene Name - the full gene name approved by the HGNC.
Enah/Vasp-like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
EVL
Synonyms (NCBI Gene) Gene synonyms aliases
RNB6
Chromosome Chromosome number
14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q32.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT046908 hsa-miR-221-3p CLASH 23622248
MIRT972348 hsa-miR-1251 CLIP-seq
MIRT972349 hsa-miR-125a-3p CLIP-seq
MIRT972350 hsa-miR-3164 CLIP-seq
MIRT972351 hsa-miR-3665 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003779 Function Actin binding IEA
GO:0005515 Function Protein binding IPI 10993894, 16336193, 25416956, 29892012
GO:0005522 Function Profilin binding IBA 21873635
GO:0005522 Function Profilin binding ISS
GO:0005737 Component Cytoplasm ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616912 20234 ENSG00000196405
Protein
UniProt ID Q9UI08
Protein name Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)
Protein function Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nuclea
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00568 WH1 1 109 WH1 domain Domain
PF08776 VASP_tetra 377 413 VASP tetramerisation domain Coiled-coil
Sequence
MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVV
INYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFAL
NIMNSQEGGPS
SQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSCS
GPPPPPPPPVPPPPTGATPPPPPPLPAGGAQGSSHDESSMSGLAAAIAGAKLRRVQRPED
ASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMED
PSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQP
HSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT
Sequence length 416
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Rap1 signaling pathway   Signaling by ROBO receptors
RHO GTPases Activate Formins
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
18507500
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451
View all (71 more)
18507500
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
18507500, 21278247
Colorectal neoplasms Colorectal Neoplasms rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049
View all (1682 more)
21278247, 18507500
Unknown
Disease term Disease name Evidence References Source
Dental caries Dental caries GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenoma Associate 21154739
Breast Neoplasms Associate 19329439
Breast Neoplasms Inhibit 23153535
Carcinogenesis Associate 27302063
Colorectal Neoplasms Associate 21278247, 26186366
Lymphoma Associate 33076962
Lymphoma B Cell Associate 33076962
Lymphoma Non Hodgkin Associate 33076962
Neoplasms Associate 19329439
Neuroinflammatory Diseases Associate 30836997