Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51458
Gene name Gene Name - the full gene name approved by the HGNC.	Rh family C glycoprotein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RHCG
Synonyms (NCBI Gene) Gene synonyms aliases	C15orf6, PDRC2, RHGK, SLC42A3
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q26.1

Show/Hide all(120)

miRTarBase ID	miRNA	Experiments	Reference
MIRT549753	hsa-miR-8485	HITS-CLIP	21572407
MIRT549754	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT549752	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT549751	hsa-miR-603	HITS-CLIP	21572407
MIRT549750	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT549748	hsa-miR-4643	HITS-CLIP	21572407
MIRT549749	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT549747	hsa-miR-3941	HITS-CLIP	21572407
MIRT549746	hsa-miR-466	HITS-CLIP	21572407
MIRT549745	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT549744	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT549743	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT661395	hsa-miR-1911-3p	HITS-CLIP	23824327
MIRT661394	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT661393	hsa-miR-4733-3p	HITS-CLIP	23824327
MIRT661392	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT661391	hsa-miR-4421	HITS-CLIP	23824327
MIRT661390	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT661389	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT661388	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT661387	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT661386	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT661385	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT661384	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT661383	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT661382	hsa-miR-6131	HITS-CLIP	23824327
MIRT661381	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT661380	hsa-miR-1297	HITS-CLIP	23824327
MIRT661379	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT661378	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT661377	hsa-miR-4465	HITS-CLIP	23824327
MIRT661376	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT661375	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT549753	hsa-miR-8485	PAR-CLIP	21572407
MIRT549754	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT549752	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT549751	hsa-miR-603	PAR-CLIP	21572407
MIRT549750	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT549748	hsa-miR-4643	PAR-CLIP	21572407
MIRT549749	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT549747	hsa-miR-3941	PAR-CLIP	21572407
MIRT549746	hsa-miR-466	PAR-CLIP	21572407
MIRT549745	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT549744	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT549743	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT442890	hsa-miR-5197-5p	PAR-CLIP	22100165
MIRT442891	hsa-miR-4786-3p	PAR-CLIP	22100165
MIRT442889	hsa-miR-6790-3p	PAR-CLIP	22100165
MIRT442888	hsa-miR-6821-3p	PAR-CLIP	22100165
MIRT442887	hsa-miR-7843-3p	PAR-CLIP	22100165
MIRT442886	hsa-miR-127-5p	PAR-CLIP	22100165
MIRT442885	hsa-miR-192-5p	PAR-CLIP	22100165
MIRT442884	hsa-miR-215-5p	PAR-CLIP	22100165
MIRT549753	hsa-miR-8485	HITS-CLIP	21572407
MIRT549754	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT549752	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT549751	hsa-miR-603	HITS-CLIP	21572407
MIRT549750	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT549748	hsa-miR-4643	HITS-CLIP	21572407
MIRT549749	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT549747	hsa-miR-3941	HITS-CLIP	21572407
MIRT549746	hsa-miR-466	HITS-CLIP	21572407
MIRT549745	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT549744	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT549743	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT661395	hsa-miR-1911-3p	HITS-CLIP	23824327
MIRT661394	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT661393	hsa-miR-4733-3p	HITS-CLIP	23824327
MIRT661392	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT661391	hsa-miR-4421	HITS-CLIP	23824327
MIRT661390	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT661389	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT661388	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT661387	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT661386	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT661385	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT661384	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT661383	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT661382	hsa-miR-6131	HITS-CLIP	23824327
MIRT661381	hsa-miR-6740-3p	HITS-CLIP	23824327
MIRT661380	hsa-miR-1297	HITS-CLIP	23824327
MIRT661379	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT661378	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT661377	hsa-miR-4465	HITS-CLIP	23824327
MIRT661376	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT661375	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT549753	hsa-miR-8485	PAR-CLIP	21572407
MIRT549754	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT549752	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT549751	hsa-miR-603	PAR-CLIP	21572407
MIRT549750	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT549748	hsa-miR-4643	PAR-CLIP	21572407
MIRT549749	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT549747	hsa-miR-3941	PAR-CLIP	21572407
MIRT549746	hsa-miR-466	PAR-CLIP	21572407
MIRT549745	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT549744	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT549743	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT442890	hsa-miR-5197-5p	PAR-CLIP	22100165
MIRT442891	hsa-miR-4786-3p	PAR-CLIP	22100165
MIRT442889	hsa-miR-6790-3p	PAR-CLIP	22100165
MIRT442888	hsa-miR-6821-3p	PAR-CLIP	22100165
MIRT442887	hsa-miR-7843-3p	PAR-CLIP	22100165
MIRT442886	hsa-miR-127-5p	PAR-CLIP	22100165
MIRT442885	hsa-miR-192-5p	PAR-CLIP	22100165
MIRT442884	hsa-miR-215-5p	PAR-CLIP	22100165
MIRT1304931	hsa-miR-1237	CLIP-seq
MIRT1304932	hsa-miR-1248	CLIP-seq
MIRT1304933	hsa-miR-134	CLIP-seq
MIRT1304934	hsa-miR-136	CLIP-seq
MIRT1304935	hsa-miR-3118	CLIP-seq
MIRT1304936	hsa-miR-382	CLIP-seq
MIRT1304937	hsa-miR-4264	CLIP-seq
MIRT1304938	hsa-miR-4279	CLIP-seq
MIRT1304939	hsa-miR-4667-5p	CLIP-seq
MIRT1304940	hsa-miR-4700-5p	CLIP-seq
MIRT1304941	hsa-miR-4797-3p	CLIP-seq
MIRT1304942	hsa-miR-515-5p	CLIP-seq
MIRT1304943	hsa-miR-637	CLIP-seq
MIRT1304944	hsa-miR-885-3p	CLIP-seq

Show/Hide all(35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 33961781
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	10852913, 12204676, 15929723
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006873	Process	Intracellular monoatomic ion homeostasis	IDA	14761968
GO:0006885	Process	Regulation of pH	IEA
GO:0008519	Function	Ammonium channel activity	IBA
GO:0008519	Function	Ammonium channel activity	IDA	14761968, 15929723, 16580862, 18032481, 24077989
GO:0008519	Function	Ammonium channel activity	IEA
GO:0008519	Function	Ammonium channel activity	IGI	11062476
GO:0008519	Function	Ammonium channel activity	TAS
GO:0015837	Process	Amine transport	NAS	10852913
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IBA
GO:0016323	Component	Basolateral plasma membrane	IDA	16928804
GO:0016324	Component	Apical plasma membrane	IBA
GO:0016324	Component	Apical plasma membrane	IDA	16928804, 18032481
GO:0016324	Component	Apical plasma membrane	IEA
GO:0030506	Function	Ankyrin binding	IDA	12719424
GO:0030506	Function	Ankyrin binding	IEA
GO:0030855	Process	Epithelial cell differentiation	NAS	12204676
GO:0031410	Component	Cytoplasmic vesicle	ISS
GO:0035378	Process	Carbon dioxide transmembrane transport	IEA
GO:0035379	Function	Carbon dioxide transmembrane transporter activity	IDA	24077989
GO:0035379	Function	Carbon dioxide transmembrane transporter activity	IEA
GO:0042592	Process	Homeostatic process	NAS	10852913
GO:0042802	Function	Identical protein binding	IPI	20457942
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145
GO:0070634	Process	Transepithelial ammonium transport	IDA	18032481
GO:0072488	Process	Ammonium transmembrane transport	IBA
GO:0072488	Process	Ammonium transmembrane transport	IDA	14761968, 15929723, 16580862, 18032481
GO:0072488	Process	Ammonium transmembrane transport	IEA
GO:0072488	Process	Ammonium transmembrane transport	IGI	11062476
GO:0097272	Process	Ammonium homeostasis	IBA

MIM	HGNC	e!Ensembl
605381	18140	ENSG00000140519

Protein

UniProt ID

Q9UBD6

Protein name

Ammonium transporter Rh type C (Rh glycoprotein kidney) (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein) (Tumor-related protein DRC2)

Protein function

Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transpor

PDB

3HD6

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00909	Ammonium_transp	43 → 434	Ammonium Transporter Family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). Expressed in kidney. {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:122

Sequence

MAWNTNLRWRLPLTCLLLQVIMVILFGVFVRYDFEADAHWWSERTHKNLSDMENEFYYRY
PSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQDRYIVV
GVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGG
SMTIHTFGAYFGLTVTRILYRRNLEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAIS
YHGDSQHRAAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMM
LMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAA
SASLEVYGKEGLVHSFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPF
WGQPSDENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP

Sequence length

479

Interactions

View interactions

	Reactome
			Rhesus glycoproteins mediate ammonium transport.

RHCG (Rh family C glycoprotein)