Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	51430
Gene name	SUN domain containing ossification factor
Gene symbol	SUCO
Synonyms (NCBI Gene)	C1orf9CH1OPTSLP1
Chromosome	1
Chromosome location	1q24.3

186

Show/Hide all (186)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027954	hsa-miR-93-5p	Sequencing	20371350
MIRT028864	hsa-miR-26b-5p	Microarray	19088304
MIRT042332	hsa-miR-484	CLASH	23622248
MIRT437607	hsa-miR-142-3p	MicroarrayqRT-PCR	22815788
MIRT713740	hsa-miR-548a-3p	HITS-CLIP	19536157
MIRT713739	hsa-miR-548ar-3p	HITS-CLIP	19536157
MIRT713738	hsa-miR-548az-3p	HITS-CLIP	19536157
MIRT713737	hsa-miR-548e-3p	HITS-CLIP	19536157
MIRT713736	hsa-miR-548f-3p	HITS-CLIP	19536157
MIRT713735	hsa-miR-5582-3p	HITS-CLIP	19536157
MIRT713734	hsa-miR-548g-3p	HITS-CLIP	19536157
MIRT713733	hsa-miR-4476	HITS-CLIP	19536157
MIRT713732	hsa-miR-6876-5p	HITS-CLIP	19536157
MIRT713731	hsa-miR-1245a	HITS-CLIP	19536157
MIRT713730	hsa-miR-8079	HITS-CLIP	19536157
MIRT713729	hsa-miR-383-5p	HITS-CLIP	19536157
MIRT713728	hsa-miR-4772-5p	HITS-CLIP	19536157
MIRT500887	hsa-miR-302b-3p	HITS-CLIP	21572407
MIRT500886	hsa-miR-302d-3p	HITS-CLIP	21572407
MIRT500885	hsa-miR-302c-3p	HITS-CLIP	21572407
MIRT500883	hsa-miR-302e	HITS-CLIP	21572407
MIRT500884	hsa-miR-372-3p	HITS-CLIP	21572407
MIRT500882	hsa-miR-373-3p	HITS-CLIP	21572407
MIRT500881	hsa-miR-520e	HITS-CLIP	21572407
MIRT500880	hsa-miR-520d-3p	HITS-CLIP	21572407
MIRT500879	hsa-miR-520c-3p	HITS-CLIP	21572407
MIRT500878	hsa-miR-302a-3p	HITS-CLIP	21572407
MIRT500877	hsa-miR-520b	HITS-CLIP	21572407
MIRT500876	hsa-miR-520a-3p	HITS-CLIP	21572407
MIRT500875	hsa-miR-519d-3p	HITS-CLIP	21572407
MIRT500874	hsa-miR-526b-3p	HITS-CLIP	21572407
MIRT027954	hsa-miR-93-5p	HITS-CLIP	21572407
MIRT500873	hsa-miR-20b-5p	HITS-CLIP	21572407
MIRT441055	hsa-miR-20a-5p	HITS-CLIP	21572407
MIRT500872	hsa-miR-17-5p	HITS-CLIP	21572407
MIRT441056	hsa-miR-106b-5p	HITS-CLIP	21572407
MIRT500871	hsa-miR-106a-5p	HITS-CLIP	21572407
MIRT500870	hsa-miR-548n	HITS-CLIP	21572407
MIRT500869	hsa-miR-548az-5p	HITS-CLIP	21572407
MIRT500868	hsa-miR-548t-5p	HITS-CLIP	21572407
MIRT500867	hsa-miR-95-5p	HITS-CLIP	21572407
MIRT500866	hsa-miR-4999-3p	HITS-CLIP	21572407
MIRT707850	hsa-miR-302a-5p	HITS-CLIP	21572407
MIRT500865	hsa-miR-7158-5p	HITS-CLIP	21572407
MIRT500887	hsa-miR-302b-3p	PAR-CLIP	24398324
MIRT500886	hsa-miR-302d-3p	PAR-CLIP	24398324
MIRT500885	hsa-miR-302c-3p	PAR-CLIP	24398324
MIRT500883	hsa-miR-302e	PAR-CLIP	24398324
MIRT500884	hsa-miR-372-3p	PAR-CLIP	24398324
MIRT500882	hsa-miR-373-3p	PAR-CLIP	24398324
MIRT500881	hsa-miR-520e	PAR-CLIP	24398324
MIRT500880	hsa-miR-520d-3p	PAR-CLIP	24398324
MIRT500879	hsa-miR-520c-3p	PAR-CLIP	24398324
MIRT500878	hsa-miR-302a-3p	PAR-CLIP	24398324
MIRT500877	hsa-miR-520b	PAR-CLIP	24398324
MIRT500876	hsa-miR-520a-3p	PAR-CLIP	24398324
MIRT500875	hsa-miR-519d-3p	PAR-CLIP	24398324
MIRT500874	hsa-miR-526b-3p	PAR-CLIP	24398324
MIRT027954	hsa-miR-93-5p	PAR-CLIP	24398324
MIRT500873	hsa-miR-20b-5p	PAR-CLIP	24398324
MIRT441055	hsa-miR-20a-5p	PAR-CLIP	24398324
MIRT500872	hsa-miR-17-5p	PAR-CLIP	24398324
MIRT441056	hsa-miR-106b-5p	PAR-CLIP	24398324
MIRT500871	hsa-miR-106a-5p	PAR-CLIP	24398324
MIRT500870	hsa-miR-548n	PAR-CLIP	24398324
MIRT500869	hsa-miR-548az-5p	PAR-CLIP	24398324
MIRT500868	hsa-miR-548t-5p	PAR-CLIP	24398324
MIRT500867	hsa-miR-95-5p	PAR-CLIP	24398324
MIRT500866	hsa-miR-4999-3p	PAR-CLIP	24398324
MIRT500865	hsa-miR-7158-5p	PAR-CLIP	24398324
MIRT485071	hsa-miR-183-5p	PAR-CLIP	23592263
MIRT485071	hsa-miR-183-5p	PAR-CLIP	23592263
MIRT485070	hsa-miR-128-3p	PAR-CLIP	23592263
MIRT485069	hsa-miR-216a-3p	PAR-CLIP	23592263
MIRT485068	hsa-miR-3681-3p	PAR-CLIP	23592263
MIRT485067	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT485066	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT485065	hsa-miR-5197-5p	PAR-CLIP	23592263
MIRT485064	hsa-miR-4255	PAR-CLIP	23592263
MIRT485063	hsa-miR-5002-5p	PAR-CLIP	23592263
MIRT485062	hsa-miR-10b-3p	PAR-CLIP	23592263
MIRT485061	hsa-miR-5093	PAR-CLIP	23592263
MIRT485060	hsa-miR-124-5p	PAR-CLIP	23592263
MIRT485059	hsa-miR-513a-5p	PAR-CLIP	23592263
MIRT485058	hsa-miR-5100	PAR-CLIP	23592263
MIRT485057	hsa-miR-3978	PAR-CLIP	23592263
MIRT485055	hsa-miR-3942-3p	PAR-CLIP	23592263
MIRT485056	hsa-miR-4263	PAR-CLIP	23592263
MIRT485054	hsa-miR-576-5p	PAR-CLIP	23592263
MIRT441056	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT437607	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT441055	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT441056	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT437607	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT500872	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT500873	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT027954	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT500875	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT441055	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT485066	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT485067	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT713740	hsa-miR-548a-3p	HITS-CLIP	19536157
MIRT713739	hsa-miR-548ar-3p	HITS-CLIP	19536157
MIRT713738	hsa-miR-548az-3p	HITS-CLIP	19536157
MIRT713737	hsa-miR-548e-3p	HITS-CLIP	19536157
MIRT713736	hsa-miR-548f-3p	HITS-CLIP	19536157
MIRT713735	hsa-miR-5582-3p	HITS-CLIP	19536157
MIRT713734	hsa-miR-548g-3p	HITS-CLIP	19536157
MIRT713733	hsa-miR-4476	HITS-CLIP	19536157
MIRT713732	hsa-miR-6876-5p	HITS-CLIP	19536157
MIRT713731	hsa-miR-1245a	HITS-CLIP	19536157
MIRT713730	hsa-miR-8079	HITS-CLIP	19536157
MIRT713729	hsa-miR-383-5p	HITS-CLIP	19536157
MIRT713728	hsa-miR-4772-5p	HITS-CLIP	19536157
MIRT500887	hsa-miR-302b-3p	HITS-CLIP	21572407
MIRT500886	hsa-miR-302d-3p	HITS-CLIP	21572407
MIRT500885	hsa-miR-302c-3p	HITS-CLIP	21572407
MIRT500883	hsa-miR-302e	HITS-CLIP	21572407
MIRT500884	hsa-miR-372-3p	HITS-CLIP	21572407
MIRT500882	hsa-miR-373-3p	HITS-CLIP	21572407
MIRT500881	hsa-miR-520e	HITS-CLIP	21572407
MIRT500880	hsa-miR-520d-3p	HITS-CLIP	21572407
MIRT500879	hsa-miR-520c-3p	HITS-CLIP	21572407
MIRT500878	hsa-miR-302a-3p	HITS-CLIP	21572407
MIRT500877	hsa-miR-520b	HITS-CLIP	21572407
MIRT500876	hsa-miR-520a-3p	HITS-CLIP	21572407
MIRT500875	hsa-miR-519d-3p	HITS-CLIP	21572407
MIRT500874	hsa-miR-526b-3p	HITS-CLIP	21572407
MIRT027954	hsa-miR-93-5p	HITS-CLIP	21572407
MIRT500873	hsa-miR-20b-5p	HITS-CLIP	21572407
MIRT441055	hsa-miR-20a-5p	HITS-CLIP	21572407
MIRT500872	hsa-miR-17-5p	HITS-CLIP	21572407
MIRT441056	hsa-miR-106b-5p	HITS-CLIP	21572407
MIRT500871	hsa-miR-106a-5p	HITS-CLIP	21572407
MIRT500870	hsa-miR-548n	HITS-CLIP	21572407
MIRT500869	hsa-miR-548az-5p	HITS-CLIP	21572407
MIRT500868	hsa-miR-548t-5p	HITS-CLIP	21572407
MIRT500867	hsa-miR-95-5p	HITS-CLIP	21572407
MIRT500866	hsa-miR-4999-3p	HITS-CLIP	21572407
MIRT707850	hsa-miR-302a-5p	HITS-CLIP	21572407
MIRT500865	hsa-miR-7158-5p	HITS-CLIP	21572407
MIRT500887	hsa-miR-302b-3p	PAR-CLIP	24398324
MIRT500886	hsa-miR-302d-3p	PAR-CLIP	24398324
MIRT500885	hsa-miR-302c-3p	PAR-CLIP	24398324
MIRT500883	hsa-miR-302e	PAR-CLIP	24398324
MIRT500884	hsa-miR-372-3p	PAR-CLIP	24398324
MIRT500882	hsa-miR-373-3p	PAR-CLIP	24398324
MIRT500881	hsa-miR-520e	PAR-CLIP	24398324
MIRT500880	hsa-miR-520d-3p	PAR-CLIP	24398324
MIRT500879	hsa-miR-520c-3p	PAR-CLIP	24398324
MIRT500878	hsa-miR-302a-3p	PAR-CLIP	24398324
MIRT500877	hsa-miR-520b	PAR-CLIP	24398324
MIRT500876	hsa-miR-520a-3p	PAR-CLIP	24398324
MIRT500875	hsa-miR-519d-3p	PAR-CLIP	24398324
MIRT500874	hsa-miR-526b-3p	PAR-CLIP	24398324
MIRT027954	hsa-miR-93-5p	PAR-CLIP	24398324
MIRT500873	hsa-miR-20b-5p	PAR-CLIP	24398324
MIRT441055	hsa-miR-20a-5p	PAR-CLIP	24398324
MIRT500872	hsa-miR-17-5p	PAR-CLIP	24398324
MIRT441056	hsa-miR-106b-5p	PAR-CLIP	24398324
MIRT500871	hsa-miR-106a-5p	PAR-CLIP	24398324
MIRT500870	hsa-miR-548n	PAR-CLIP	24398324
MIRT500869	hsa-miR-548az-5p	PAR-CLIP	24398324
MIRT500868	hsa-miR-548t-5p	PAR-CLIP	24398324
MIRT500867	hsa-miR-95-5p	PAR-CLIP	24398324
MIRT500866	hsa-miR-4999-3p	PAR-CLIP	24398324
MIRT500865	hsa-miR-7158-5p	PAR-CLIP	24398324
MIRT485071	hsa-miR-183-5p	PAR-CLIP	23592263
MIRT485071	hsa-miR-183-5p	PAR-CLIP	23592263
MIRT485070	hsa-miR-128-3p	PAR-CLIP	23592263
MIRT485069	hsa-miR-216a-3p	PAR-CLIP	23592263
MIRT485068	hsa-miR-3681-3p	PAR-CLIP	23592263
MIRT485067	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT485066	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT485065	hsa-miR-5197-5p	PAR-CLIP	23592263
MIRT485064	hsa-miR-4255	PAR-CLIP	23592263
MIRT485063	hsa-miR-5002-5p	PAR-CLIP	23592263
MIRT485062	hsa-miR-10b-3p	PAR-CLIP	23592263
MIRT485061	hsa-miR-5093	PAR-CLIP	23592263
MIRT485060	hsa-miR-124-5p	PAR-CLIP	23592263
MIRT485059	hsa-miR-513a-5p	PAR-CLIP	23592263
MIRT485058	hsa-miR-5100	PAR-CLIP	23592263
MIRT485057	hsa-miR-3978	PAR-CLIP	23592263
MIRT485055	hsa-miR-3942-3p	PAR-CLIP	23592263
MIRT485056	hsa-miR-4263	PAR-CLIP	23592263
MIRT485054	hsa-miR-576-5p	PAR-CLIP	23592263

Show/Hide all (16)

GO ID	Ontology	Definition	Evidence
GO:0001503	Process	Ossification	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005791	Component	Rough endoplasmic reticulum	IEA
GO:0005791	Component	Rough endoplasmic reticulum	ISS
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0030867	Component	Rough endoplasmic reticulum membrane	IEA
GO:0032967	Process	Positive regulation of collagen biosynthetic process	IEA
GO:0032967	Process	Positive regulation of collagen biosynthetic process	ISS
GO:0045669	Process	Positive regulation of osteoblast differentiation	IEA
GO:0045669	Process	Positive regulation of osteoblast differentiation	ISS
GO:0046850	Process	Regulation of bone remodeling	IBA
GO:0046850	Process	Regulation of bone remodeling	IEA
GO:0046850	Process	Regulation of bone remodeling	ISS

MIM	HGNC	e!Ensembl
619434	1240	ENSG00000094975

Q9UBS9

Protein name

SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1)

Protein function

Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07738	Sad1_UNC	322 → 452	Sad1 / UNC-like C-terminal	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in pancreas and testis and to a lower extent in prostate, ovary, heart, thymus, small intestine and spleen. {ECO:0000269|PubMed:10673381}.

Sequence

MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD
EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES
SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS
APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN
LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT
KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ
VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV
KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP
LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP
ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE
QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV
LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE
LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK
SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE
AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA
NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK
LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL
CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK
SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP
FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR
ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI

Sequence length

1254

Interactions

View interactions

Show/Hide Unknown Diseases (12)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Conflicting classifications of pathogenicity	rs145307638	RCV005922887
Cholangiocarcinoma	Benign	rs201746190	RCV005926164
Clear cell carcinoma of kidney	Conflicting classifications of pathogenicity	rs145307638	RCV005922889
Familial cancer of breast	Conflicting classifications of pathogenicity; Benign	rs145307638, rs201746190	RCV005922886 RCV005926160
Gastric cancer	Benign	rs201746190	RCV005926161
Malignant lymphoma, large B-cell, diffuse	Benign	rs2285664	RCV005926167
Malignant tumor of esophagus	Conflicting classifications of pathogenicity	rs145307638	RCV005922888
Melanoma	Conflicting classifications of pathogenicity	rs145307638	RCV005922890
Ovarian serous cystadenocarcinoma	Benign	rs201746190	RCV005926162
SUCO-related disorder	Uncertain significance; Benign; Likely benign	rs41263742, rs78411230, rs113997299, rs41264546, rs114570278, rs369972222, rs45505403, rs2285664, rs12033849, rs770422299, rs2285143, rs2239816, rs372623434, rs75760494, rs369053337, rs76761114 View all (1 more)	RCV003911090 RCV003933476 RCV003913771 RCV003978671 RCV003913648 RCV003958824 RCV003958871 RCV003971104 RCV003933445 RCV004758248 RCV003979643 RCV003979671 RCV003979717 RCV003911578 RCV003937009 RCV003921950 RCV003922303 RCV003955770
Thymoma	Benign	rs201746190	RCV005926163
Uterine corpus endometrial carcinoma	Likely benign	rs766194690	RCV005868553

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acute cholinergic dysautonomia	Associate	36050318
Carcinogenesis	Associate	31434866
Carcinoma Hepatocellular	Stimulate	31434866
FOR heavy chain disease protein human	Associate	3139711
Heavy Chain Disease	Associate	14613292
HEM dysplasia	Associate	29620724
Huntington Disease	Associate	36434993
Leukemia Prolymphocytic T Cell	Associate	4242251
Leukemia T Cell	Associate	4242251
Melanoma Cutaneous Malignant	Associate	36437242
Nasopharyngeal Carcinoma	Associate	14694118
Neoplasms	Inhibit	23474763
Oncogene Addiction	Associate	25426963
Philadelphia Chromosome	Associate	4242251
Squamous Cell Carcinoma of Head and Neck	Associate	23474763

SUCO (SUN domain containing ossification factor)