PDE4C (phosphodiesterase 4C)

Gene

• Entrez ID: 5143
• Gene name: Phosphodiesterase 4C
• Gene symbol: PDE4C
• Synonyms (NCBI Gene): DPDE1, PDE21
• Chromosome: 19
• Chromosome location: 19p13.11
• Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular sign

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT722937	hsa-miR-125a-3p	HITS-CLIP	19536157
MIRT722936	hsa-miR-764	HITS-CLIP	19536157
MIRT722935	hsa-miR-3934-5p	HITS-CLIP	19536157
MIRT722934	hsa-miR-3664-3p	HITS-CLIP	19536157
MIRT722933	hsa-miR-1266-5p	HITS-CLIP	19536157
MIRT722932	hsa-miR-4518	HITS-CLIP	19536157
MIRT722931	hsa-miR-4682	HITS-CLIP	19536157
MIRT722930	hsa-miR-619-5p	HITS-CLIP	19536157
MIRT722929	hsa-miR-6506-5p	HITS-CLIP	19536157
MIRT722928	hsa-miR-4320	HITS-CLIP	19536157
MIRT722927	hsa-miR-6869-5p	HITS-CLIP	19536157
MIRT684637	hsa-miR-5089-5p	HITS-CLIP	19536157
MIRT684667	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT684666	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT684665	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT684664	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT684663	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT684662	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT684661	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT684660	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT684659	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT684658	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT684657	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT684656	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT684655	hsa-miR-302e	HITS-CLIP	23313552
MIRT684654	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT684653	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT684652	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT684651	hsa-miR-520b	HITS-CLIP	23313552
MIRT684650	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT684649	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT684648	hsa-miR-520e	HITS-CLIP	23313552
MIRT684647	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT684646	hsa-miR-1295b-3p	HITS-CLIP	23313552
MIRT684645	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT684644	hsa-miR-520h	HITS-CLIP	23313552
MIRT684643	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT684642	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT684641	hsa-miR-3622b-5p	HITS-CLIP	23313552
MIRT684640	hsa-miR-4640-5p	HITS-CLIP	23313552
MIRT684639	hsa-miR-4726-5p	HITS-CLIP	23313552
MIRT684638	hsa-miR-6508-3p	HITS-CLIP	23313552
MIRT684637	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT678440	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT678439	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT678438	hsa-miR-5697	HITS-CLIP	23824327
MIRT626054	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT678437	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT678436	hsa-miR-4532	HITS-CLIP	23824327
MIRT614098	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT614097	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT678435	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT678434	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT678433	hsa-miR-1976	HITS-CLIP	23824327
MIRT678432	hsa-miR-1297	HITS-CLIP	23824327
MIRT678431	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT678430	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT678429	hsa-miR-4465	HITS-CLIP	23824327
MIRT678428	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT678427	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT678426	hsa-miR-4279	HITS-CLIP	23824327
MIRT678425	hsa-miR-498	HITS-CLIP	23824327
MIRT614096	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT614095	hsa-miR-4794	HITS-CLIP	23824327
MIRT614094	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT614089	hsa-miR-4775	HITS-CLIP	23824327
MIRT626054	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT626053	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626052	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT626051	hsa-miR-3140-5p	HITS-CLIP	23824327
MIRT626050	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626049	hsa-miR-4680-3p	HITS-CLIP	23824327
MIRT626048	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT626047	hsa-miR-4284	HITS-CLIP	23824327
MIRT626046	hsa-miR-4452	HITS-CLIP	23824327
MIRT614099	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT614096	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT614095	hsa-miR-4794	HITS-CLIP	23824327
MIRT614094	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT614089	hsa-miR-4775	HITS-CLIP	23824327
MIRT614088	hsa-miR-3672	HITS-CLIP	23824327
MIRT614087	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT614085	hsa-miR-8055	HITS-CLIP	23824327
MIRT614099	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT542071	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT614098	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT614097	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT614096	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT614095	hsa-miR-4794	HITS-CLIP	23824327
MIRT614094	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT614093	hsa-miR-6804-3p	HITS-CLIP	23824327
MIRT614092	hsa-miR-1254	HITS-CLIP	23824327
MIRT614091	hsa-miR-3116	HITS-CLIP	23824327
MIRT614090	hsa-miR-661	HITS-CLIP	23824327
MIRT614089	hsa-miR-4775	HITS-CLIP	23824327
MIRT614088	hsa-miR-3672	HITS-CLIP	23824327
MIRT614087	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT614086	hsa-miR-4715-3p	HITS-CLIP	23824327
MIRT614085	hsa-miR-8055	HITS-CLIP	23824327
MIRT495758	hsa-miR-652-5p	PAR-CLIP	20371350
MIRT569488	hsa-miR-1203	PAR-CLIP	20371350
MIRT495757	hsa-miR-542-5p	PAR-CLIP	20371350
MIRT495756	hsa-miR-645	PAR-CLIP	20371350
MIRT495755	hsa-miR-6087	PAR-CLIP	20371350
MIRT495754	hsa-miR-4706	PAR-CLIP	20371350
MIRT495753	hsa-miR-4749-5p	PAR-CLIP	20371350
MIRT495752	hsa-miR-1908-5p	PAR-CLIP	20371350
MIRT495751	hsa-miR-663a	PAR-CLIP	20371350
MIRT495750	hsa-miR-6787-5p	PAR-CLIP	20371350
MIRT495749	hsa-miR-638	PAR-CLIP	20371350
MIRT542071	hsa-miR-6872-3p	PAR-CLIP	21572407
MIRT542070	hsa-miR-4258	PAR-CLIP	21572407
MIRT542069	hsa-miR-3149	PAR-CLIP	21572407
MIRT529288	hsa-miR-6793-3p	PAR-CLIP	22012620
MIRT529287	hsa-miR-6887-3p	PAR-CLIP	22012620
MIRT529286	hsa-miR-1470	PAR-CLIP	22012620
MIRT529285	hsa-miR-551a	PAR-CLIP	22012620
MIRT529284	hsa-miR-551b-3p	PAR-CLIP	22012620
MIRT529283	hsa-miR-1292-3p	PAR-CLIP	22012620
MIRT529282	hsa-miR-1180-5p	PAR-CLIP	22012620
MIRT529281	hsa-miR-7114-3p	PAR-CLIP	22012620
MIRT529280	hsa-miR-4783-5p	PAR-CLIP	22012620
MIRT529279	hsa-miR-4433a-5p	PAR-CLIP	22012620
MIRT529278	hsa-miR-4750-3p	PAR-CLIP	22012620
MIRT495758	hsa-miR-652-5p	PAR-CLIP	22291592
MIRT495757	hsa-miR-542-5p	PAR-CLIP	22291592
MIRT495756	hsa-miR-645	PAR-CLIP	22291592
MIRT495755	hsa-miR-6087	PAR-CLIP	22291592
MIRT495754	hsa-miR-4706	PAR-CLIP	22291592
MIRT495753	hsa-miR-4749-5p	PAR-CLIP	22291592
MIRT495752	hsa-miR-1908-5p	PAR-CLIP	22291592
MIRT495751	hsa-miR-663a	PAR-CLIP	22291592
MIRT495750	hsa-miR-6787-5p	PAR-CLIP	22291592
MIRT495749	hsa-miR-638	PAR-CLIP	22291592
MIRT722937	hsa-miR-125a-3p	HITS-CLIP	19536157
MIRT722936	hsa-miR-764	HITS-CLIP	19536157
MIRT722935	hsa-miR-3934-5p	HITS-CLIP	19536157
MIRT722934	hsa-miR-3664-3p	HITS-CLIP	19536157
MIRT722933	hsa-miR-1266-5p	HITS-CLIP	19536157
MIRT722932	hsa-miR-4518	HITS-CLIP	19536157
MIRT722931	hsa-miR-4682	HITS-CLIP	19536157
MIRT722930	hsa-miR-619-5p	HITS-CLIP	19536157
MIRT722929	hsa-miR-6506-5p	HITS-CLIP	19536157
MIRT722928	hsa-miR-4320	HITS-CLIP	19536157
MIRT722927	hsa-miR-6869-5p	HITS-CLIP	19536157
MIRT684637	hsa-miR-5089-5p	HITS-CLIP	19536157
MIRT684667	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT684666	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT684665	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT684664	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT684663	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT684662	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT684661	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT684660	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT684659	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT684658	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT684657	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT684656	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT684655	hsa-miR-302e	HITS-CLIP	23313552
MIRT684654	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT684653	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT684652	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT684651	hsa-miR-520b	HITS-CLIP	23313552
MIRT684650	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT684649	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT684648	hsa-miR-520e	HITS-CLIP	23313552
MIRT684647	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT684646	hsa-miR-1295b-3p	HITS-CLIP	23313552
MIRT684645	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT684644	hsa-miR-520h	HITS-CLIP	23313552
MIRT684643	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT684642	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT684641	hsa-miR-3622b-5p	HITS-CLIP	23313552
MIRT684640	hsa-miR-4640-5p	HITS-CLIP	23313552
MIRT684639	hsa-miR-4726-5p	HITS-CLIP	23313552
MIRT684638	hsa-miR-6508-3p	HITS-CLIP	23313552
MIRT684637	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT678440	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT678439	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT678438	hsa-miR-5697	HITS-CLIP	23824327
MIRT626054	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT678437	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT678436	hsa-miR-4532	HITS-CLIP	23824327
MIRT614098	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT614097	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT678435	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT678434	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT678433	hsa-miR-1976	HITS-CLIP	23824327
MIRT678432	hsa-miR-1297	HITS-CLIP	23824327
MIRT678431	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT678430	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT678429	hsa-miR-4465	HITS-CLIP	23824327
MIRT678428	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT678427	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT678426	hsa-miR-4279	HITS-CLIP	23824327
MIRT678425	hsa-miR-498	HITS-CLIP	23824327
MIRT614096	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT614095	hsa-miR-4794	HITS-CLIP	23824327
MIRT614094	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT614089	hsa-miR-4775	HITS-CLIP	23824327
MIRT626054	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT626053	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626052	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT626051	hsa-miR-3140-5p	HITS-CLIP	23824327
MIRT626050	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626049	hsa-miR-4680-3p	HITS-CLIP	23824327
MIRT626048	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT626047	hsa-miR-4284	HITS-CLIP	23824327
MIRT626046	hsa-miR-4452	HITS-CLIP	23824327
MIRT614099	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT614096	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT614095	hsa-miR-4794	HITS-CLIP	23824327
MIRT614094	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT614089	hsa-miR-4775	HITS-CLIP	23824327
MIRT614088	hsa-miR-3672	HITS-CLIP	23824327
MIRT614087	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT614085	hsa-miR-8055	HITS-CLIP	23824327
MIRT614099	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT542071	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT614098	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT614097	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT614096	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT614095	hsa-miR-4794	HITS-CLIP	23824327
MIRT614094	hsa-miR-664a-5p	HITS-CLIP	23824327
MIRT614093	hsa-miR-6804-3p	HITS-CLIP	23824327
MIRT614092	hsa-miR-1254	HITS-CLIP	23824327
MIRT614091	hsa-miR-3116	HITS-CLIP	23824327
MIRT614090	hsa-miR-661	HITS-CLIP	23824327
MIRT614089	hsa-miR-4775	HITS-CLIP	23824327
MIRT614088	hsa-miR-3672	HITS-CLIP	23824327
MIRT614087	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT614086	hsa-miR-4715-3p	HITS-CLIP	23824327
MIRT614085	hsa-miR-8055	HITS-CLIP	23824327
MIRT495758	hsa-miR-652-5p	PAR-CLIP	20371350
MIRT569488	hsa-miR-1203	PAR-CLIP	20371350
MIRT495757	hsa-miR-542-5p	PAR-CLIP	20371350
MIRT495756	hsa-miR-645	PAR-CLIP	20371350
MIRT495755	hsa-miR-6087	PAR-CLIP	20371350
MIRT495754	hsa-miR-4706	PAR-CLIP	20371350
MIRT495753	hsa-miR-4749-5p	PAR-CLIP	20371350
MIRT495752	hsa-miR-1908-5p	PAR-CLIP	20371350
MIRT495751	hsa-miR-663a	PAR-CLIP	20371350
MIRT495750	hsa-miR-6787-5p	PAR-CLIP	20371350
MIRT495749	hsa-miR-638	PAR-CLIP	20371350
MIRT542071	hsa-miR-6872-3p	PAR-CLIP	21572407
MIRT542070	hsa-miR-4258	PAR-CLIP	21572407
MIRT542069	hsa-miR-3149	PAR-CLIP	21572407
MIRT529288	hsa-miR-6793-3p	PAR-CLIP	22012620
MIRT529287	hsa-miR-6887-3p	PAR-CLIP	22012620
MIRT529286	hsa-miR-1470	PAR-CLIP	22012620
MIRT529285	hsa-miR-551a	PAR-CLIP	22012620
MIRT529284	hsa-miR-551b-3p	PAR-CLIP	22012620
MIRT529283	hsa-miR-1292-3p	PAR-CLIP	22012620
MIRT529282	hsa-miR-1180-5p	PAR-CLIP	22012620
MIRT529281	hsa-miR-7114-3p	PAR-CLIP	22012620
MIRT529280	hsa-miR-4783-5p	PAR-CLIP	22012620
MIRT529279	hsa-miR-4433a-5p	PAR-CLIP	22012620
MIRT529278	hsa-miR-4750-3p	PAR-CLIP	22012620
MIRT495758	hsa-miR-652-5p	PAR-CLIP	22291592
MIRT495757	hsa-miR-542-5p	PAR-CLIP	22291592
MIRT495756	hsa-miR-645	PAR-CLIP	22291592
MIRT495755	hsa-miR-6087	PAR-CLIP	22291592
MIRT495754	hsa-miR-4706	PAR-CLIP	22291592
MIRT495753	hsa-miR-4749-5p	PAR-CLIP	22291592
MIRT495752	hsa-miR-1908-5p	PAR-CLIP	22291592
MIRT495751	hsa-miR-663a	PAR-CLIP	22291592
MIRT495750	hsa-miR-6787-5p	PAR-CLIP	22291592
MIRT495749	hsa-miR-638	PAR-CLIP	22291592
MIRT1220525	hsa-miR-1193	CLIP-seq
MIRT1220526	hsa-miR-122	CLIP-seq
MIRT1220527	hsa-miR-1237	CLIP-seq
MIRT1220528	hsa-miR-1248	CLIP-seq
MIRT1220529	hsa-miR-1252	CLIP-seq
MIRT1220530	hsa-miR-1299	CLIP-seq
MIRT1220531	hsa-miR-1307	CLIP-seq
MIRT1220532	hsa-miR-130a	CLIP-seq
MIRT1220533	hsa-miR-130b	CLIP-seq
MIRT1220534	hsa-miR-183	CLIP-seq
MIRT1220535	hsa-miR-301a	CLIP-seq
MIRT1220536	hsa-miR-301b	CLIP-seq
MIRT1220537	hsa-miR-3122	CLIP-seq
MIRT1220538	hsa-miR-3124-3p	CLIP-seq
MIRT1220539	hsa-miR-3135b	CLIP-seq
MIRT1220540	hsa-miR-3170	CLIP-seq
MIRT1220541	hsa-miR-3187-3p	CLIP-seq
MIRT1220542	hsa-miR-3194-3p	CLIP-seq
MIRT1220543	hsa-miR-3202	CLIP-seq
MIRT1220544	hsa-miR-3545-3p	CLIP-seq
MIRT1220545	hsa-miR-3652	CLIP-seq
MIRT1220546	hsa-miR-3663-5p	CLIP-seq
MIRT1220547	hsa-miR-3666	CLIP-seq
MIRT1220548	hsa-miR-3913-5p	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT1220550	hsa-miR-4270	CLIP-seq
MIRT1220551	hsa-miR-4295	CLIP-seq
MIRT1220552	hsa-miR-4430	CLIP-seq
MIRT1220553	hsa-miR-4435	CLIP-seq
MIRT1220554	hsa-miR-4441	CLIP-seq
MIRT1220555	hsa-miR-450b-3p	CLIP-seq
MIRT1220556	hsa-miR-4533	CLIP-seq
MIRT1220557	hsa-miR-454	CLIP-seq
MIRT1220558	hsa-miR-4635	CLIP-seq
MIRT1220559	hsa-miR-4638-5p	CLIP-seq
MIRT1220560	hsa-miR-4680-5p	CLIP-seq
MIRT1220561	hsa-miR-4701-5p	CLIP-seq
MIRT1220562	hsa-miR-4708-5p	CLIP-seq
MIRT1220563	hsa-miR-4753-3p	CLIP-seq
MIRT1220564	hsa-miR-4755-3p	CLIP-seq
MIRT1220565	hsa-miR-4781-3p	CLIP-seq
MIRT1220566	hsa-miR-501-3p	CLIP-seq
MIRT1220567	hsa-miR-502-3p	CLIP-seq
MIRT1220568	hsa-miR-5096	CLIP-seq
MIRT1220569	hsa-miR-520a-5p	CLIP-seq
MIRT1220570	hsa-miR-525-5p	CLIP-seq
MIRT1220571	hsa-miR-532-5p	CLIP-seq
MIRT1220572	hsa-miR-548n	CLIP-seq
MIRT1220573	hsa-miR-548s	CLIP-seq
MIRT1220574	hsa-miR-548t	CLIP-seq
MIRT1220575	hsa-miR-564	CLIP-seq
MIRT1220576	hsa-miR-588	CLIP-seq
MIRT1220577	hsa-miR-640	CLIP-seq
MIRT1220578	hsa-miR-769-3p	CLIP-seq
MIRT1220579	hsa-miR-875-3p	CLIP-seq
MIRT1220580	hsa-miR-942	CLIP-seq
MIRT1220526	hsa-miR-122	CLIP-seq
MIRT1220581	hsa-miR-1234	CLIP-seq
MIRT1220529	hsa-miR-1252	CLIP-seq
MIRT1220530	hsa-miR-1299	CLIP-seq
MIRT1220532	hsa-miR-130a	CLIP-seq
MIRT1220533	hsa-miR-130b	CLIP-seq
MIRT1220582	hsa-miR-150	CLIP-seq
MIRT1220583	hsa-miR-1827	CLIP-seq
MIRT1220534	hsa-miR-183	CLIP-seq
MIRT1220584	hsa-miR-2355-5p	CLIP-seq
MIRT1220585	hsa-miR-2682	CLIP-seq
MIRT1220586	hsa-miR-26a	CLIP-seq
MIRT1220587	hsa-miR-26b	CLIP-seq
MIRT1220535	hsa-miR-301a	CLIP-seq
MIRT1220536	hsa-miR-301b	CLIP-seq
MIRT1220539	hsa-miR-3135b	CLIP-seq
MIRT1220541	hsa-miR-3187-3p	CLIP-seq
MIRT1220543	hsa-miR-3202	CLIP-seq
MIRT1220544	hsa-miR-3545-3p	CLIP-seq
MIRT1220545	hsa-miR-3652	CLIP-seq
MIRT1220546	hsa-miR-3663-5p	CLIP-seq
MIRT1220547	hsa-miR-3666	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT1220588	hsa-miR-4269	CLIP-seq
MIRT1220589	hsa-miR-4294	CLIP-seq
MIRT1220551	hsa-miR-4295	CLIP-seq
MIRT1220552	hsa-miR-4430	CLIP-seq
MIRT1220553	hsa-miR-4435	CLIP-seq
MIRT1220590	hsa-miR-4438	CLIP-seq
MIRT1220591	hsa-miR-449c	CLIP-seq
MIRT1220556	hsa-miR-4533	CLIP-seq
MIRT1220557	hsa-miR-454	CLIP-seq
MIRT1220558	hsa-miR-4635	CLIP-seq
MIRT1220592	hsa-miR-4649-3p	CLIP-seq
MIRT1220560	hsa-miR-4680-5p	CLIP-seq
MIRT1220561	hsa-miR-4701-5p	CLIP-seq
MIRT1220593	hsa-miR-4723-5p	CLIP-seq
MIRT1220564	hsa-miR-4755-3p	CLIP-seq
MIRT1220565	hsa-miR-4781-3p	CLIP-seq
MIRT1220566	hsa-miR-501-3p	CLIP-seq
MIRT1220567	hsa-miR-502-3p	CLIP-seq
MIRT1220594	hsa-miR-5095	CLIP-seq
MIRT1220595	hsa-miR-513c	CLIP-seq
MIRT1220573	hsa-miR-548s	CLIP-seq
MIRT1220596	hsa-miR-562	CLIP-seq
MIRT1220575	hsa-miR-564	CLIP-seq
MIRT1220576	hsa-miR-588	CLIP-seq
MIRT1220577	hsa-miR-640	CLIP-seq
MIRT1220597	hsa-miR-767-5p	CLIP-seq
MIRT1220598	hsa-miR-873	CLIP-seq
MIRT1220579	hsa-miR-875-3p	CLIP-seq
MIRT1220526	hsa-miR-122	CLIP-seq
MIRT2063654	hsa-miR-1236	CLIP-seq
MIRT2063655	hsa-miR-1273f	CLIP-seq
MIRT1220531	hsa-miR-1307	CLIP-seq
MIRT1220532	hsa-miR-130a	CLIP-seq
MIRT1220533	hsa-miR-130b	CLIP-seq
MIRT2063656	hsa-miR-1343	CLIP-seq
MIRT1220582	hsa-miR-150	CLIP-seq
MIRT1220534	hsa-miR-183	CLIP-seq
MIRT2063657	hsa-miR-197	CLIP-seq
MIRT1220584	hsa-miR-2355-5p	CLIP-seq
MIRT1220586	hsa-miR-26a	CLIP-seq
MIRT1220587	hsa-miR-26b	CLIP-seq
MIRT1220535	hsa-miR-301a	CLIP-seq
MIRT1220536	hsa-miR-301b	CLIP-seq
MIRT1220539	hsa-miR-3135b	CLIP-seq
MIRT2063658	hsa-miR-3150a-5p	CLIP-seq
MIRT2063659	hsa-miR-3150b-5p	CLIP-seq
MIRT2063660	hsa-miR-3157-5p	CLIP-seq
MIRT1220540	hsa-miR-3170	CLIP-seq
MIRT1220541	hsa-miR-3187-3p	CLIP-seq
MIRT1220542	hsa-miR-3194-3p	CLIP-seq
MIRT1220544	hsa-miR-3545-3p	CLIP-seq
MIRT1220545	hsa-miR-3652	CLIP-seq
MIRT1220546	hsa-miR-3663-5p	CLIP-seq
MIRT1220547	hsa-miR-3666	CLIP-seq
MIRT2063661	hsa-miR-378g	CLIP-seq
MIRT2063662	hsa-miR-3934	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT1220588	hsa-miR-4269	CLIP-seq
MIRT2063663	hsa-miR-4286	CLIP-seq
MIRT1220551	hsa-miR-4295	CLIP-seq
MIRT1220552	hsa-miR-4430	CLIP-seq
MIRT1220553	hsa-miR-4435	CLIP-seq
MIRT2063664	hsa-miR-4437	CLIP-seq
MIRT1220590	hsa-miR-4438	CLIP-seq
MIRT1220557	hsa-miR-454	CLIP-seq
MIRT1220558	hsa-miR-4635	CLIP-seq
MIRT1220559	hsa-miR-4638-5p	CLIP-seq
MIRT2063665	hsa-miR-4674	CLIP-seq
MIRT1220560	hsa-miR-4680-5p	CLIP-seq
MIRT1220561	hsa-miR-4701-5p	CLIP-seq
MIRT1220564	hsa-miR-4755-3p	CLIP-seq
MIRT1220594	hsa-miR-5095	CLIP-seq
MIRT1220568	hsa-miR-5096	CLIP-seq
MIRT1220573	hsa-miR-548s	CLIP-seq
MIRT1220575	hsa-miR-564	CLIP-seq
MIRT2063666	hsa-miR-587	CLIP-seq
MIRT1220576	hsa-miR-588	CLIP-seq
MIRT1220577	hsa-miR-640	CLIP-seq
MIRT2292101	hsa-miR-106a	CLIP-seq
MIRT2292102	hsa-miR-106b	CLIP-seq
MIRT1220526	hsa-miR-122	CLIP-seq
MIRT2063655	hsa-miR-1273f	CLIP-seq
MIRT2292103	hsa-miR-1281	CLIP-seq
MIRT1220531	hsa-miR-1307	CLIP-seq
MIRT1220532	hsa-miR-130a	CLIP-seq
MIRT1220533	hsa-miR-130b	CLIP-seq
MIRT2292104	hsa-miR-139-3p	CLIP-seq
MIRT1220582	hsa-miR-150	CLIP-seq
MIRT2292105	hsa-miR-17	CLIP-seq
MIRT1220534	hsa-miR-183	CLIP-seq
MIRT2063657	hsa-miR-197	CLIP-seq
MIRT2292106	hsa-miR-20a	CLIP-seq
MIRT2292107	hsa-miR-20b	CLIP-seq
MIRT2292108	hsa-miR-2276	CLIP-seq
MIRT1220584	hsa-miR-2355-5p	CLIP-seq
MIRT1220586	hsa-miR-26a	CLIP-seq
MIRT1220587	hsa-miR-26b	CLIP-seq
MIRT2292109	hsa-miR-2964a-5p	CLIP-seq
MIRT1220535	hsa-miR-301a	CLIP-seq
MIRT1220536	hsa-miR-301b	CLIP-seq
MIRT2292110	hsa-miR-302a	CLIP-seq
MIRT2292111	hsa-miR-302b	CLIP-seq
MIRT2292112	hsa-miR-302c	CLIP-seq
MIRT2292113	hsa-miR-302d	CLIP-seq
MIRT1220539	hsa-miR-3135b	CLIP-seq
MIRT2063658	hsa-miR-3150a-5p	CLIP-seq
MIRT2063659	hsa-miR-3150b-5p	CLIP-seq
MIRT1220540	hsa-miR-3170	CLIP-seq
MIRT1220541	hsa-miR-3187-3p	CLIP-seq
MIRT1220542	hsa-miR-3194-3p	CLIP-seq
MIRT1220544	hsa-miR-3545-3p	CLIP-seq
MIRT1220545	hsa-miR-3652	CLIP-seq
MIRT1220546	hsa-miR-3663-5p	CLIP-seq
MIRT1220547	hsa-miR-3666	CLIP-seq
MIRT2292114	hsa-miR-372	CLIP-seq
MIRT2292115	hsa-miR-373	CLIP-seq
MIRT2292116	hsa-miR-3929	CLIP-seq
MIRT2063662	hsa-miR-3934	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT1220588	hsa-miR-4269	CLIP-seq
MIRT1220589	hsa-miR-4294	CLIP-seq
MIRT1220551	hsa-miR-4295	CLIP-seq
MIRT2292117	hsa-miR-431	CLIP-seq
MIRT2292118	hsa-miR-4419b	CLIP-seq
MIRT1220552	hsa-miR-4430	CLIP-seq
MIRT1220553	hsa-miR-4435	CLIP-seq
MIRT1220590	hsa-miR-4438	CLIP-seq
MIRT2292119	hsa-miR-4478	CLIP-seq
MIRT2292120	hsa-miR-4514	CLIP-seq
MIRT1220557	hsa-miR-454	CLIP-seq
MIRT2292121	hsa-miR-4634	CLIP-seq
MIRT1220559	hsa-miR-4638-5p	CLIP-seq
MIRT1220560	hsa-miR-4680-5p	CLIP-seq
MIRT2292122	hsa-miR-4692	CLIP-seq
MIRT1220561	hsa-miR-4701-5p	CLIP-seq
MIRT2292123	hsa-miR-4716-5p	CLIP-seq
MIRT2292124	hsa-miR-4742-5p	CLIP-seq
MIRT1220564	hsa-miR-4755-3p	CLIP-seq
MIRT1220565	hsa-miR-4781-3p	CLIP-seq
MIRT1220594	hsa-miR-5095	CLIP-seq
MIRT1220568	hsa-miR-5096	CLIP-seq
MIRT1220595	hsa-miR-513c	CLIP-seq
MIRT2292125	hsa-miR-519d	CLIP-seq
MIRT2292126	hsa-miR-520g	CLIP-seq
MIRT1220573	hsa-miR-548s	CLIP-seq
MIRT1220596	hsa-miR-562	CLIP-seq
MIRT1220575	hsa-miR-564	CLIP-seq
MIRT1220576	hsa-miR-588	CLIP-seq
MIRT1220577	hsa-miR-640	CLIP-seq
MIRT2292127	hsa-miR-924	CLIP-seq
MIRT2292128	hsa-miR-93	CLIP-seq
MIRT2456084	hsa-miR-1224-3p	CLIP-seq
MIRT2063654	hsa-miR-1236	CLIP-seq
MIRT2456085	hsa-miR-1260	CLIP-seq
MIRT2456086	hsa-miR-1260b	CLIP-seq
MIRT2063655	hsa-miR-1273f	CLIP-seq
MIRT2456087	hsa-miR-1280	CLIP-seq
MIRT2456088	hsa-miR-1910	CLIP-seq
MIRT2456089	hsa-miR-1913	CLIP-seq
MIRT2456090	hsa-miR-3074-5p	CLIP-seq
MIRT1220540	hsa-miR-3170	CLIP-seq
MIRT2456091	hsa-miR-324-3p	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT2456092	hsa-miR-4268	CLIP-seq
MIRT2456093	hsa-miR-4274	CLIP-seq
MIRT2456094	hsa-miR-4313	CLIP-seq
MIRT2456095	hsa-miR-4423-5p	CLIP-seq
MIRT2456096	hsa-miR-4448	CLIP-seq
MIRT2456097	hsa-miR-4503	CLIP-seq
MIRT2456098	hsa-miR-4720-3p	CLIP-seq
MIRT2456099	hsa-miR-532-3p	CLIP-seq
MIRT2456100	hsa-miR-544	CLIP-seq
MIRT2456101	hsa-miR-767-3p	CLIP-seq
MIRT2292101	hsa-miR-106a	CLIP-seq
MIRT2292102	hsa-miR-106b	CLIP-seq
MIRT1220526	hsa-miR-122	CLIP-seq
MIRT1220529	hsa-miR-1252	CLIP-seq
MIRT2063655	hsa-miR-1273f	CLIP-seq
MIRT1220530	hsa-miR-1299	CLIP-seq
MIRT1220582	hsa-miR-150	CLIP-seq
MIRT2292105	hsa-miR-17	CLIP-seq
MIRT2063657	hsa-miR-197	CLIP-seq
MIRT2292106	hsa-miR-20a	CLIP-seq
MIRT2292107	hsa-miR-20b	CLIP-seq
MIRT1220584	hsa-miR-2355-5p	CLIP-seq
MIRT1220586	hsa-miR-26a	CLIP-seq
MIRT1220587	hsa-miR-26b	CLIP-seq
MIRT2292110	hsa-miR-302a	CLIP-seq
MIRT2292111	hsa-miR-302b	CLIP-seq
MIRT2292112	hsa-miR-302c	CLIP-seq
MIRT2292113	hsa-miR-302d	CLIP-seq
MIRT1220539	hsa-miR-3135b	CLIP-seq
MIRT2063658	hsa-miR-3150a-5p	CLIP-seq
MIRT2063659	hsa-miR-3150b-5p	CLIP-seq
MIRT1220540	hsa-miR-3170	CLIP-seq
MIRT1220541	hsa-miR-3187-3p	CLIP-seq
MIRT1220543	hsa-miR-3202	CLIP-seq
MIRT1220545	hsa-miR-3652	CLIP-seq
MIRT1220546	hsa-miR-3663-5p	CLIP-seq
MIRT2292114	hsa-miR-372	CLIP-seq
MIRT2292115	hsa-miR-373	CLIP-seq
MIRT2063662	hsa-miR-3934	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT1220552	hsa-miR-4430	CLIP-seq
MIRT1220553	hsa-miR-4435	CLIP-seq
MIRT1220556	hsa-miR-4533	CLIP-seq
MIRT2292121	hsa-miR-4634	CLIP-seq
MIRT1220559	hsa-miR-4638-5p	CLIP-seq
MIRT1220561	hsa-miR-4701-5p	CLIP-seq
MIRT2292123	hsa-miR-4716-5p	CLIP-seq
MIRT1220564	hsa-miR-4755-3p	CLIP-seq
MIRT1220565	hsa-miR-4781-3p	CLIP-seq
MIRT1220568	hsa-miR-5096	CLIP-seq
MIRT2292125	hsa-miR-519d	CLIP-seq
MIRT2292126	hsa-miR-520g	CLIP-seq
MIRT1220572	hsa-miR-548n	CLIP-seq
MIRT1220573	hsa-miR-548s	CLIP-seq
MIRT1220574	hsa-miR-548t	CLIP-seq
MIRT1220576	hsa-miR-588	CLIP-seq
MIRT1220577	hsa-miR-640	CLIP-seq
MIRT1220579	hsa-miR-875-3p	CLIP-seq
MIRT2292128	hsa-miR-93	CLIP-seq
MIRT1220526	hsa-miR-122	CLIP-seq
MIRT1220529	hsa-miR-1252	CLIP-seq
MIRT1220530	hsa-miR-1299	CLIP-seq
MIRT1220586	hsa-miR-26a	CLIP-seq
MIRT1220587	hsa-miR-26b	CLIP-seq
MIRT1220539	hsa-miR-3135b	CLIP-seq
MIRT1220543	hsa-miR-3202	CLIP-seq
MIRT1220545	hsa-miR-3652	CLIP-seq
MIRT1220549	hsa-miR-411	CLIP-seq
MIRT1220552	hsa-miR-4430	CLIP-seq
MIRT1220556	hsa-miR-4533	CLIP-seq
MIRT2292121	hsa-miR-4634	CLIP-seq
MIRT1220566	hsa-miR-501-3p	CLIP-seq
MIRT1220567	hsa-miR-502-3p	CLIP-seq
MIRT1220572	hsa-miR-548n	CLIP-seq
MIRT1220574	hsa-miR-548t	CLIP-seq
MIRT1220579	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004114	Function	3',5'-cyclic-nucleotide phosphodiesterase activity	IEA
GO:0004115	Function	3',5'-cyclic-AMP phosphodiesterase activity	IBA
GO:0004115	Function	3',5'-cyclic-AMP phosphodiesterase activity	IDA	7843419
GO:0004115	Function	3',5'-cyclic-AMP phosphodiesterase activity	IEA
GO:0004115	Function	3',5'-cyclic-AMP phosphodiesterase activity	TAS	9349724
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005615	Component	Extracellular space	HDA	22664934
GO:0005829	Component	Cytosol	TAS
GO:0005929	Component	Cilium	IEA
GO:0005929	Component	Cilium	ISS
GO:0006198	Process	CAMP catabolic process	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0008081	Function	Phosphoric diester hydrolase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0042995	Component	Cell projection	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0047555	Function	3',5'-cyclic-GMP phosphodiesterase activity	IBA
GO:0141162	Process	Negative regulation of cAMP/PKA signal transduction	IBA

Other IDs

• MIM: 600128
• HGNC: 8782
• e!Ensembl: ENSG00000105650

Protein

• UniProt ID: Q08493
• Protein name: 3',5'-cyclic-AMP phosphodiesterase 4C (EC 3.1.4.53) (DPDE1) (PDE21) (cAMP-specific phosphodiesterase 4C)
• Protein function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
• PDB: 2QYM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18100	PDE4_UCR	152 → 268	Phosphodiesterase 4 upstream conserved regions (UCR)	Domain
  PF00233	PDEase_I	387 → 628		Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in various tissues but not in cells of the immune system. {ECO:0000269|PubMed:7843419}.
• Sequence:

  MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
  LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESF
  LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGA
  AKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
  LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSA
  SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLL
  KTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILA
  ALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
  SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
  LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
  IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
  TLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT

• Sequence length: 712

Pathways

KEGG:

Purine metabolism
Metabolic pathways
cAMP signaling pathway
Parathyroid hormone synthesis, secretion and action
Morphine addiction

Reactome:

DARPP-32 events
G alpha (s) signalling events

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
GOUT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenomyosis	Associate	39326465	★☆☆☆☆ Found in Text Mining only
Congenital Hyperinsulinism	Associate	23869231	★☆☆☆☆ Found in Text Mining only
Down Syndrome	Associate	27293319	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	36275722	★☆☆☆☆ Found in Text Mining only
Respiratory Hypersensitivity	Associate	21784969	★☆☆☆☆ Found in Text Mining only
Thyroid Cancer Papillary	Associate	40427523	★☆☆☆☆ Found in Text Mining only