Gene Gene information from NCBI Gene database.
Entrez ID 51429
Gene name Sorting nexin 9
Gene symbol SNX9
Synonyms (NCBI Gene)
SDP1SH3PX1SH3PXD3AWISP
Chromosome 6
Chromosome location 6q25.3
Summary This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, b
miRNA miRNA information provided by mirtarbase database.
471
miRTarBase ID miRNA Experiments Reference
MIRT016587 hsa-miR-193b-3p Microarray 20304954
MIRT018610 hsa-miR-335-5p Microarray 18185580
MIRT022921 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT049111 hsa-miR-92a-3p CLASH 23622248
MIRT042698 hsa-miR-196b-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
66
GO ID Ontology Definition Evidence Reference
GO:0000278 Process Mitotic cell cycle IEA
GO:0000281 Process Mitotic cytokinesis IEA
GO:0000281 Process Mitotic cytokinesis IMP 22718350
GO:0001726 Component Ruffle IEA
GO:0005515 Function Protein binding IPI 10531379, 11799118, 14679214, 15703209, 16374509, 16585770, 17242350, 18353773, 18388313, 19487689, 19807924, 20129922, 20427313, 20491914, 23085988, 25107275, 25544563, 25825872, 27107012, 33961781, 35271311
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605952 14973 ENSG00000130340
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y5X1
Protein name Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)
Protein function Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of
PDB 2RAI , 2RAJ , 2RAK , 3DYT , 3DYU , 3LGE , 7OJ9
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00018 SH3_1 6 54 SH3 domain Domain
PF00787 PX 273 357 PX domain Domain
PF10456 BAR_3_WASP_bdg 358 593 WASP-binding domain of Sorting nexin protein Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:10531379}.
Sequence
Sequence length 595
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Salmonella infection   Golgi Associated Vesicle Biogenesis
Clathrin-mediated endocytosis