Gene Gene information from NCBI Gene database.
Entrez ID 51427
Gene name Zinc finger protein 107
Gene symbol ZNF107
Synonyms (NCBI Gene)
Y8ZFD25ZNF588smap-7
Chromosome 7
Chromosome location 7q11.21
Summary This gene encodes a protein containing multiple C2H2-type zinc finger regions. Proteins containing zinc fingers may act as transcriptional regulators, but may also have other cellular functions. Alternative splicing results in multiple transcript variants
miRNA miRNA information provided by mirtarbase database.
929
miRTarBase ID miRNA Experiments Reference
MIRT019600 hsa-miR-340-5p Sequencing 20371350
MIRT563741 hsa-miR-4703-3p HITS-CLIP 23313552
MIRT563740 hsa-miR-337-3p HITS-CLIP 23313552
MIRT563739 hsa-miR-202-5p HITS-CLIP 23313552
MIRT563738 hsa-miR-3685 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603989 12887 ENSG00000196247
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UII5
Protein name Zinc finger protein 107 (Zinc finger protein 588) (Zinc finger protein ZFD25)
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 104 126 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 132 154 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 160 182 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 189 210 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 244 266 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 328 350 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 356 378 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 384 405 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 412 434 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 440 462 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 468 490 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 496 518 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 608 630 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 664 686 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 692 714 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 720 742 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in brain, heart, skeletal muscle, kidney and pancreas. Weakly expressed in aorta, liver and lung.
Sequence
MVAKPPVMSFHFAQDLWPEQNIKDSFQKVTLRRYGKCEYENLQLRKGCKHVDECTGHKGG
HNTVNQCLTATPSKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT
QHRRIH
TRVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKI
IH
TEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTG
ENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLN
KCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKE
CGKAFNQSSNLTEHKKIH
TAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKA
FNRSSTLTRHKKIH
TGEKPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRF
STLTKHKRIH
TGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRT
IHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKI
IYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTG
EKPYKCKECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSEKPY
KCEECGKSFNQFSSLNIHKIIH
TGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY
GKT
Sequence length 783
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
High myopia Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYPERTENSION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SEVERE MYOPIA Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations