NIP7 (nucleolar pre-rRNA processing protein NIP7)

Gene

• Entrez ID: 51388
• Gene name: Nucleolar pre-rRNA processing protein NIP7
• Gene symbol: NIP7
• Synonyms (NCBI Gene): CGI-37, HSPC031, KD93
• Chromosome: 16
• Chromosome location: 16q22.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023066	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT028652	hsa-miR-30a-5p	Proteomics	18668040
MIRT030007	hsa-miR-26b-5p	Sequencing	20371350
MIRT048591	hsa-miR-100-5p	CLASH	23622248
MIRT040453	hsa-miR-615-3p	CLASH	23622248
MIRT696318	hsa-miR-3150a-5p	HITS-CLIP	23313552
MIRT696317	hsa-miR-3150b-5p	HITS-CLIP	23313552
MIRT696316	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT696315	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT696314	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT696313	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT696312	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT696310	hsa-miR-3663-5p	HITS-CLIP	23313552
MIRT696311	hsa-miR-4755-3p	HITS-CLIP	23313552
MIRT696309	hsa-miR-6131	HITS-CLIP	23313552
MIRT195549	hsa-miR-548s	HITS-CLIP	23313552
MIRT696308	hsa-miR-4701-5p	HITS-CLIP	23313552
MIRT696307	hsa-miR-588	HITS-CLIP	23313552
MIRT696306	hsa-miR-4435	HITS-CLIP	23313552
MIRT696305	hsa-miR-3187-3p	HITS-CLIP	23313552
MIRT696304	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT696303	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT630073	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT630072	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630071	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630070	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630069	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630068	hsa-miR-3666	HITS-CLIP	23824327
MIRT630067	hsa-miR-4295	HITS-CLIP	23824327
MIRT630066	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630065	hsa-miR-183-5p	HITS-CLIP	23824327
MIRT630064	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT630063	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630062	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630061	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630060	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT630059	hsa-miR-3652	HITS-CLIP	23824327
MIRT630058	hsa-miR-4430	HITS-CLIP	23824327
MIRT630057	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630056	hsa-miR-8057	HITS-CLIP	23824327
MIRT030007	hsa-miR-26b-5p	PAR-CLIP	26701625
MIRT696318	hsa-miR-3150a-5p	HITS-CLIP	27418678
MIRT696317	hsa-miR-3150b-5p	HITS-CLIP	27418678
MIRT696305	hsa-miR-3187-3p	HITS-CLIP	27418678
MIRT696310	hsa-miR-3663-5p	HITS-CLIP	27418678
MIRT696313	hsa-miR-371a-5p	HITS-CLIP	27418678
MIRT696316	hsa-miR-371b-5p	HITS-CLIP	27418678
MIRT696312	hsa-miR-372-5p	HITS-CLIP	27418678
MIRT696315	hsa-miR-373-5p	HITS-CLIP	27418678
MIRT696306	hsa-miR-4435	HITS-CLIP	27418678
MIRT696308	hsa-miR-4701-5p	HITS-CLIP	27418678
MIRT696311	hsa-miR-4755-3p	HITS-CLIP	27418678
MIRT195549	hsa-miR-548s	HITS-CLIP	27418678
MIRT696307	hsa-miR-588	HITS-CLIP	27418678
MIRT696309	hsa-miR-6131	HITS-CLIP	27418678
MIRT696314	hsa-miR-616-5p	HITS-CLIP	27418678
MIRT696304	hsa-miR-6843-3p	HITS-CLIP	27418678
MIRT696303	hsa-miR-6848-3p	HITS-CLIP	27418678
MIRT696318	hsa-miR-3150a-5p	HITS-CLIP	23313552
MIRT696317	hsa-miR-3150b-5p	HITS-CLIP	23313552
MIRT696316	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT696315	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT696314	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT696313	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT696312	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT696310	hsa-miR-3663-5p	HITS-CLIP	23313552
MIRT696311	hsa-miR-4755-3p	HITS-CLIP	23313552
MIRT696309	hsa-miR-6131	HITS-CLIP	23313552
MIRT195549	hsa-miR-548s	HITS-CLIP	23313552
MIRT696308	hsa-miR-4701-5p	HITS-CLIP	23313552
MIRT696307	hsa-miR-588	HITS-CLIP	23313552
MIRT696306	hsa-miR-4435	HITS-CLIP	23313552
MIRT696305	hsa-miR-3187-3p	HITS-CLIP	23313552
MIRT696304	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT696303	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT630073	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT630072	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630071	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630070	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630069	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630068	hsa-miR-3666	HITS-CLIP	23824327
MIRT630067	hsa-miR-4295	HITS-CLIP	23824327
MIRT630066	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630065	hsa-miR-183-5p	HITS-CLIP	23824327
MIRT630064	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT630063	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630062	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630061	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630060	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT630059	hsa-miR-3652	HITS-CLIP	23824327
MIRT630058	hsa-miR-4430	HITS-CLIP	23824327
MIRT630057	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630056	hsa-miR-8057	HITS-CLIP	23824327
MIRT1185209	hsa-miR-150	CLIP-seq
MIRT1185210	hsa-miR-1976	CLIP-seq
MIRT1185211	hsa-miR-4261	CLIP-seq
MIRT1185212	hsa-miR-4279	CLIP-seq
MIRT1185213	hsa-miR-4496	CLIP-seq
MIRT1185214	hsa-miR-4722-3p	CLIP-seq
MIRT1185215	hsa-miR-498	CLIP-seq
MIRT1185216	hsa-miR-101	CLIP-seq
MIRT1185217	hsa-miR-1204	CLIP-seq
MIRT1185218	hsa-miR-1245	CLIP-seq
MIRT1185219	hsa-miR-125a-5p	CLIP-seq
MIRT1185220	hsa-miR-125b	CLIP-seq
MIRT1185221	hsa-miR-1273f	CLIP-seq
MIRT1185222	hsa-miR-144	CLIP-seq
MIRT1185223	hsa-miR-148a	CLIP-seq
MIRT1185224	hsa-miR-148b	CLIP-seq
MIRT1185225	hsa-miR-152	CLIP-seq
MIRT1185226	hsa-miR-197	CLIP-seq
MIRT1185227	hsa-miR-200b	CLIP-seq
MIRT1185228	hsa-miR-200c	CLIP-seq
MIRT1185229	hsa-miR-2114	CLIP-seq
MIRT1185230	hsa-miR-223	CLIP-seq
MIRT1185231	hsa-miR-26a	CLIP-seq
MIRT1185232	hsa-miR-26b	CLIP-seq
MIRT1185233	hsa-miR-3140-3p	CLIP-seq
MIRT1185234	hsa-miR-3156-5p	CLIP-seq
MIRT1185235	hsa-miR-3170	CLIP-seq
MIRT1185236	hsa-miR-3180-5p	CLIP-seq
MIRT1185237	hsa-miR-3199	CLIP-seq
MIRT1185238	hsa-miR-320a	CLIP-seq
MIRT1185239	hsa-miR-320b	CLIP-seq
MIRT1185240	hsa-miR-320c	CLIP-seq
MIRT1185241	hsa-miR-320d	CLIP-seq
MIRT1185242	hsa-miR-3612	CLIP-seq
MIRT1185243	hsa-miR-3622a-5p	CLIP-seq
MIRT1185244	hsa-miR-3646	CLIP-seq
MIRT1185245	hsa-miR-3653	CLIP-seq
MIRT1185246	hsa-miR-3659	CLIP-seq
MIRT1185247	hsa-miR-3662	CLIP-seq
MIRT1185248	hsa-miR-369-3p	CLIP-seq
MIRT1185249	hsa-miR-371-5p	CLIP-seq
MIRT1185250	hsa-miR-374a	CLIP-seq
MIRT1185251	hsa-miR-374b	CLIP-seq
MIRT1185252	hsa-miR-376a	CLIP-seq
MIRT1185253	hsa-miR-376b	CLIP-seq
MIRT1185254	hsa-miR-383	CLIP-seq
MIRT1185255	hsa-miR-3976	CLIP-seq
MIRT1185256	hsa-miR-410	CLIP-seq
MIRT1185257	hsa-miR-411	CLIP-seq
MIRT1185258	hsa-miR-412	CLIP-seq
MIRT1185259	hsa-miR-4251	CLIP-seq
MIRT1185260	hsa-miR-4252	CLIP-seq
MIRT1185261	hsa-miR-4263	CLIP-seq
MIRT1185262	hsa-miR-4271	CLIP-seq
MIRT1185263	hsa-miR-4276	CLIP-seq
MIRT1185264	hsa-miR-429	CLIP-seq
MIRT1185265	hsa-miR-4319	CLIP-seq
MIRT1185266	hsa-miR-433	CLIP-seq
MIRT1185267	hsa-miR-4429	CLIP-seq
MIRT1185268	hsa-miR-4438	CLIP-seq
MIRT1185269	hsa-miR-4440	CLIP-seq
MIRT1185270	hsa-miR-4475	CLIP-seq
MIRT1185271	hsa-miR-4477a	CLIP-seq
MIRT1185272	hsa-miR-4533	CLIP-seq
MIRT1185273	hsa-miR-4540	CLIP-seq
MIRT1185274	hsa-miR-4634	CLIP-seq
MIRT1185275	hsa-miR-4680-3p	CLIP-seq
MIRT1185276	hsa-miR-4697-3p	CLIP-seq
MIRT1185277	hsa-miR-4709-3p	CLIP-seq
MIRT1185278	hsa-miR-4716-5p	CLIP-seq
MIRT1185279	hsa-miR-4719	CLIP-seq
MIRT1185280	hsa-miR-4725-3p	CLIP-seq
MIRT1185281	hsa-miR-4732-3p	CLIP-seq
MIRT1185282	hsa-miR-4740-5p	CLIP-seq
MIRT1185283	hsa-miR-4747-5p	CLIP-seq
MIRT1185284	hsa-miR-4757-5p	CLIP-seq
MIRT1185285	hsa-miR-4766-5p	CLIP-seq
MIRT1185286	hsa-miR-4772-5p	CLIP-seq
MIRT1185287	hsa-miR-4781-3p	CLIP-seq
MIRT1185288	hsa-miR-5095	CLIP-seq
MIRT1185289	hsa-miR-5096	CLIP-seq
MIRT1185290	hsa-miR-520f	CLIP-seq
MIRT1185291	hsa-miR-539	CLIP-seq
MIRT1185292	hsa-miR-548ae	CLIP-seq
MIRT1185293	hsa-miR-548aj	CLIP-seq
MIRT1185294	hsa-miR-548am	CLIP-seq
MIRT1185295	hsa-miR-548u	CLIP-seq
MIRT1185296	hsa-miR-548x	CLIP-seq
MIRT1185297	hsa-miR-564	CLIP-seq
MIRT1185298	hsa-miR-570	CLIP-seq
MIRT1185299	hsa-miR-576-5p	CLIP-seq
MIRT1185300	hsa-miR-596	CLIP-seq
MIRT1185301	hsa-miR-650	CLIP-seq
MIRT1185302	hsa-miR-670	CLIP-seq
MIRT1185303	hsa-miR-759	CLIP-seq
MIRT2053656	hsa-miR-122	CLIP-seq
MIRT2053657	hsa-miR-1228	CLIP-seq
MIRT2053658	hsa-miR-1245b-3p	CLIP-seq
MIRT1185221	hsa-miR-1273f	CLIP-seq
MIRT2053659	hsa-miR-1289	CLIP-seq
MIRT2053660	hsa-miR-130a	CLIP-seq
MIRT2053661	hsa-miR-130b	CLIP-seq
MIRT2053662	hsa-miR-183	CLIP-seq
MIRT1185226	hsa-miR-197	CLIP-seq
MIRT2053663	hsa-miR-301a	CLIP-seq
MIRT2053664	hsa-miR-301b	CLIP-seq
MIRT1185235	hsa-miR-3170	CLIP-seq
MIRT2053665	hsa-miR-3198	CLIP-seq
MIRT2053666	hsa-miR-3664-5p	CLIP-seq
MIRT1185248	hsa-miR-369-3p	CLIP-seq
MIRT1185250	hsa-miR-374a	CLIP-seq
MIRT1185251	hsa-miR-374b	CLIP-seq
MIRT1185254	hsa-miR-383	CLIP-seq
MIRT1185256	hsa-miR-410	CLIP-seq
MIRT1185257	hsa-miR-411	CLIP-seq
MIRT1185258	hsa-miR-412	CLIP-seq
MIRT2053667	hsa-miR-4294	CLIP-seq
MIRT2053668	hsa-miR-4309	CLIP-seq
MIRT1185268	hsa-miR-4438	CLIP-seq
MIRT2053669	hsa-miR-4534	CLIP-seq
MIRT2053670	hsa-miR-454	CLIP-seq
MIRT2053671	hsa-miR-4639-3p	CLIP-seq
MIRT1185278	hsa-miR-4716-5p	CLIP-seq
MIRT2053672	hsa-miR-4735-5p	CLIP-seq
MIRT2053673	hsa-miR-4742-3p	CLIP-seq
MIRT1185286	hsa-miR-4772-5p	CLIP-seq
MIRT2053674	hsa-miR-4775	CLIP-seq
MIRT1185287	hsa-miR-4781-3p	CLIP-seq
MIRT1185288	hsa-miR-5095	CLIP-seq
MIRT1185289	hsa-miR-5096	CLIP-seq
MIRT1185298	hsa-miR-570	CLIP-seq
MIRT2053675	hsa-miR-590-3p	CLIP-seq
MIRT2053676	hsa-miR-592	CLIP-seq
MIRT1185300	hsa-miR-596	CLIP-seq
MIRT2053677	hsa-miR-597	CLIP-seq
MIRT2053656	hsa-miR-122	CLIP-seq
MIRT2053660	hsa-miR-130a	CLIP-seq
MIRT2053661	hsa-miR-130b	CLIP-seq
MIRT2053662	hsa-miR-183	CLIP-seq
MIRT2282872	hsa-miR-28-3p	CLIP-seq
MIRT2053663	hsa-miR-301a	CLIP-seq
MIRT2053664	hsa-miR-301b	CLIP-seq
MIRT2053670	hsa-miR-454	CLIP-seq
MIRT1185233	hsa-miR-3140-3p	CLIP-seq
MIRT1185273	hsa-miR-4540	CLIP-seq
MIRT2431611	hsa-miR-1343	CLIP-seq
MIRT2431612	hsa-miR-4326	CLIP-seq
MIRT2455202	hsa-miR-3922-5p	CLIP-seq
MIRT2455203	hsa-miR-4753-5p	CLIP-seq
MIRT2455204	hsa-miR-548a-3p	CLIP-seq
MIRT2455205	hsa-miR-548e	CLIP-seq
MIRT2455206	hsa-miR-548f	CLIP-seq
MIRT1185298	hsa-miR-570	CLIP-seq
MIRT2455207	hsa-miR-618	CLIP-seq
MIRT2581067	hsa-miR-1284	CLIP-seq
MIRT2581068	hsa-miR-140-3p	CLIP-seq
MIRT2581069	hsa-miR-298	CLIP-seq
MIRT1185235	hsa-miR-3170	CLIP-seq
MIRT2581070	hsa-miR-329	CLIP-seq
MIRT2581071	hsa-miR-362-3p	CLIP-seq
MIRT1185248	hsa-miR-369-3p	CLIP-seq
MIRT1185250	hsa-miR-374a	CLIP-seq
MIRT1185251	hsa-miR-374b	CLIP-seq
MIRT2455202	hsa-miR-3922-5p	CLIP-seq
MIRT1185256	hsa-miR-410	CLIP-seq
MIRT2581072	hsa-miR-4275	CLIP-seq
MIRT2581073	hsa-miR-4659a-3p	CLIP-seq
MIRT2581074	hsa-miR-4659b-3p	CLIP-seq
MIRT2053673	hsa-miR-4742-3p	CLIP-seq
MIRT2455203	hsa-miR-4753-5p	CLIP-seq
MIRT2581075	hsa-miR-4795-5p	CLIP-seq
MIRT2455204	hsa-miR-548a-3p	CLIP-seq
MIRT2455205	hsa-miR-548e	CLIP-seq
MIRT2455206	hsa-miR-548f	CLIP-seq
MIRT2455207	hsa-miR-618	CLIP-seq
MIRT2581067	hsa-miR-1284	CLIP-seq
MIRT2581068	hsa-miR-140-3p	CLIP-seq
MIRT2581069	hsa-miR-298	CLIP-seq
MIRT1185235	hsa-miR-3170	CLIP-seq
MIRT1185248	hsa-miR-369-3p	CLIP-seq
MIRT1185250	hsa-miR-374a	CLIP-seq
MIRT1185251	hsa-miR-374b	CLIP-seq
MIRT2455202	hsa-miR-3922-5p	CLIP-seq
MIRT1185256	hsa-miR-410	CLIP-seq
MIRT2581073	hsa-miR-4659a-3p	CLIP-seq
MIRT2581074	hsa-miR-4659b-3p	CLIP-seq
MIRT2053673	hsa-miR-4742-3p	CLIP-seq
MIRT2455203	hsa-miR-4753-5p	CLIP-seq
MIRT2581075	hsa-miR-4795-5p	CLIP-seq
MIRT2455204	hsa-miR-548a-3p	CLIP-seq
MIRT2455205	hsa-miR-548e	CLIP-seq
MIRT2455206	hsa-miR-548f	CLIP-seq
MIRT2455207	hsa-miR-618	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	14660641, 17643419, 25416956, 30021884, 32814053, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0030687	Component	Preribosome, large subunit precursor	IBA
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042255	Process	Ribosome assembly	IEA
GO:0042273	Process	Ribosomal large subunit biogenesis	IBA

Other IDs

• MIM: 619204
• HGNC: 24328
• e!Ensembl: ENSG00000132603

Protein

• UniProt ID: Q9Y221
• Protein name: 60S ribosome subunit biogenesis protein NIP7 homolog (KD93) (Nucleolar pre-rRNA processing protein NIP7)
• Protein function: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
• PDB: 1SQW, 1T5Y, 8FKT, 8FKU, 8FKV, 8FKW, 8FKX, 8FKY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF17833	UPF0113_N	2 → 83	UPF0113 Pre-PUA domain	Domain
  PF03657	UPF0113	96 → 175	UPF0113 PUA domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in hematopoietic stem/progenitor cells. {ECO:0000269|PubMed:15522784}.
• Sequence:

  MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKIMKLAANISG
  DKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGR
  ITENTSQYQGVVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT
  

• Sequence length: 180

Pathways

Reactome:

Major pathway of rRNA processing in the nucleolus and cytosol