CRLF3 (cytokine receptor like factor 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51379 |
| Gene name | Cytokine receptor like factor 3 |
| Gene symbol | CRLF3 |
| Synonyms (NCBI Gene) |
CREME-9CREME9CRLM9CYTOR4FRWSp48.2
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| Chromosome | 17 |
| Chromosome location | 17q11.2 |
| Summary | This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one |
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miRNA
miRNA information provided by mirtarbase database.
551
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8IUI8 | |
| Protein name | Cytokine receptor-like factor 3 (Cytokine receptor-like molecule 9) (CREME-9) (Cytokine receptor-related protein 4) (Type I cytokine receptor-like factor p48) | |
| Protein function | May play a role in the negative regulation of cell cycle progression. | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer ty | |
| Sequence |
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| Sequence length | 442 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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