Gene Gene information from NCBI Gene database.
Entrez ID 51361
Gene name Hook microtubule tethering protein 1
Gene symbol HOOK1
Synonyms (NCBI Gene)
HK1
Chromosome 1
Chromosome location 1p32.1
Summary This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interac
miRNA miRNA information provided by mirtarbase database.
283
miRTarBase ID miRNA Experiments Reference
MIRT017608 hsa-miR-335-5p Microarray 18185580
MIRT023735 hsa-miR-1-3p Microarray 18668037
MIRT028032 hsa-miR-93-5p Sequencing 20371350
MIRT557194 hsa-miR-4453 HITS-CLIP 21572407
MIRT557193 hsa-miR-4538 HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
38
GO ID Ontology Definition Evidence Reference
GO:0003779 Function Actin binding IEA
GO:0005515 Function Protein binding IPI 15471887, 17043677, 18799622, 25416956, 25910212, 28514442, 29423001, 31413325, 31515488, 32073997, 32296183, 32814053, 33961781
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 15471887
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607820 19884 ENSG00000134709
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UJC3
Protein name Protein Hook homolog 1 (h-hook1) (hHK1)
Protein function Component of the FTS/Hook/FHIP complex (FHF complex) (PubMed:18799622, PubMed:32073997). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) (PubMed:187
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF19047 HOOK_N 13 163 HOOK domain Domain
PF05622 HOOK 186 719 HOOK protein coiled-coil region Coiled-coil
Sequence
Sequence length 728
Interactions View interactions