Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51340
Gene name Gene Name - the full gene name approved by the HGNC.	Crooked neck pre-mRNA splicing factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CRNKL1
Synonyms (NCBI Gene) Gene synonyms aliases	CLF, CRN, Clf1, HCRN, MSTP021, SYF3
Chromosome Chromosome number	20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	20p11.23
Summary Summary of gene provided in NCBI Entrez Gene.	The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the

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miRTarBase ID	miRNA	Experiments	Reference
MIRT045227	hsa-miR-186-5p	CLASH	23622248
MIRT704464	hsa-miR-8063	HITS-CLIP	23313552
MIRT704463	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT704462	hsa-miR-1284	HITS-CLIP	23313552
MIRT704461	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT704460	hsa-miR-4786-5p	HITS-CLIP	23313552
MIRT704459	hsa-miR-769-5p	HITS-CLIP	23313552
MIRT704458	hsa-miR-3926	HITS-CLIP	23313552
MIRT704457	hsa-miR-3672	HITS-CLIP	23313552
MIRT704456	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT704455	hsa-miR-548s	HITS-CLIP	23313552
MIRT548707	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT548706	hsa-miR-548ab	PAR-CLIP	21572407
MIRT548705	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT548704	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT548703	hsa-miR-548ak	PAR-CLIP	21572407
MIRT548702	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT548701	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT548700	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT548699	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT548698	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT548697	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT548696	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT548695	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT548694	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT548693	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT548692	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT548691	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT548690	hsa-miR-548i	PAR-CLIP	21572407
MIRT548689	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT548688	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT548687	hsa-miR-548w	PAR-CLIP	21572407
MIRT548686	hsa-miR-548y	PAR-CLIP	21572407
MIRT548685	hsa-miR-559	PAR-CLIP	21572407
MIRT548684	hsa-miR-548ag	PAR-CLIP	21572407
MIRT548683	hsa-miR-548ai	PAR-CLIP	21572407
MIRT548682	hsa-miR-548ba	PAR-CLIP	21572407
MIRT548681	hsa-miR-570-5p	PAR-CLIP	21572407
MIRT548680	hsa-miR-944	PAR-CLIP	21572407
MIRT548678	hsa-miR-4704-5p	PAR-CLIP	21572407
MIRT548679	hsa-miR-3923	PAR-CLIP	21572407
MIRT548677	hsa-miR-126-5p	PAR-CLIP	21572407
MIRT548676	hsa-miR-6777-3p	PAR-CLIP	21572407
MIRT548675	hsa-miR-628-3p	PAR-CLIP	21572407
MIRT548674	hsa-miR-3117-5p	PAR-CLIP	21572407
MIRT548673	hsa-miR-4477a	PAR-CLIP	21572407
MIRT445516	hsa-miR-548ae-3p	PAR-CLIP	22291592
MIRT445515	hsa-miR-548ah-3p	PAR-CLIP	22291592
MIRT445514	hsa-miR-548aj-3p	PAR-CLIP	22291592
MIRT445513	hsa-miR-548am-3p	PAR-CLIP	22291592
MIRT445512	hsa-miR-548aq-3p	PAR-CLIP	22291592
MIRT445511	hsa-miR-548j-3p	PAR-CLIP	22291592
MIRT445510	hsa-miR-548x-3p	PAR-CLIP	22291592
MIRT445509	hsa-miR-5582-3p	PAR-CLIP	22291592
MIRT445508	hsa-miR-329-5p	PAR-CLIP	22291592
MIRT445507	hsa-miR-3613-3p	PAR-CLIP	22291592
MIRT445506	hsa-miR-655-5p	PAR-CLIP	22291592
MIRT445505	hsa-miR-377-5p	PAR-CLIP	22291592
MIRT445504	hsa-miR-6086	PAR-CLIP	22291592
MIRT445516	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445515	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445514	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445513	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445512	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445511	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445510	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445509	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445508	hsa-miR-329-5p	PAR-CLIP	22100165
MIRT445507	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT445506	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT445505	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT445504	hsa-miR-6086	PAR-CLIP	22100165
MIRT445516	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445515	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445514	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445513	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445512	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445511	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445510	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445509	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445508	hsa-miR-329-5p	PAR-CLIP	22100165
MIRT445507	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT445506	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT445505	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT445504	hsa-miR-6086	PAR-CLIP	22100165
MIRT704464	hsa-miR-8063	HITS-CLIP	23313552
MIRT704463	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT704462	hsa-miR-1284	HITS-CLIP	23313552
MIRT704461	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT704460	hsa-miR-4786-5p	HITS-CLIP	23313552
MIRT704459	hsa-miR-769-5p	HITS-CLIP	23313552
MIRT704458	hsa-miR-3926	HITS-CLIP	23313552
MIRT704457	hsa-miR-3672	HITS-CLIP	23313552
MIRT704456	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT704455	hsa-miR-548s	HITS-CLIP	23313552
MIRT548707	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT548706	hsa-miR-548ab	PAR-CLIP	21572407
MIRT548705	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT548704	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT548703	hsa-miR-548ak	PAR-CLIP	21572407
MIRT548702	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT548701	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT548700	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT548699	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT548698	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT548697	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT548696	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT548695	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT548694	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT548693	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT548692	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT548691	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT548690	hsa-miR-548i	PAR-CLIP	21572407
MIRT548689	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT548688	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT548687	hsa-miR-548w	PAR-CLIP	21572407
MIRT548686	hsa-miR-548y	PAR-CLIP	21572407
MIRT548685	hsa-miR-559	PAR-CLIP	21572407
MIRT548684	hsa-miR-548ag	PAR-CLIP	21572407
MIRT548683	hsa-miR-548ai	PAR-CLIP	21572407
MIRT548682	hsa-miR-548ba	PAR-CLIP	21572407
MIRT548681	hsa-miR-570-5p	PAR-CLIP	21572407
MIRT548680	hsa-miR-944	PAR-CLIP	21572407
MIRT548678	hsa-miR-4704-5p	PAR-CLIP	21572407
MIRT548679	hsa-miR-3923	PAR-CLIP	21572407
MIRT548677	hsa-miR-126-5p	PAR-CLIP	21572407
MIRT548676	hsa-miR-6777-3p	PAR-CLIP	21572407
MIRT548675	hsa-miR-628-3p	PAR-CLIP	21572407
MIRT548674	hsa-miR-3117-5p	PAR-CLIP	21572407
MIRT548673	hsa-miR-4477a	PAR-CLIP	21572407
MIRT445516	hsa-miR-548ae-3p	PAR-CLIP	22291592
MIRT445515	hsa-miR-548ah-3p	PAR-CLIP	22291592
MIRT445514	hsa-miR-548aj-3p	PAR-CLIP	22291592
MIRT445513	hsa-miR-548am-3p	PAR-CLIP	22291592
MIRT445512	hsa-miR-548aq-3p	PAR-CLIP	22291592
MIRT445511	hsa-miR-548j-3p	PAR-CLIP	22291592
MIRT445510	hsa-miR-548x-3p	PAR-CLIP	22291592
MIRT445509	hsa-miR-5582-3p	PAR-CLIP	22291592
MIRT445508	hsa-miR-329-5p	PAR-CLIP	22291592
MIRT445507	hsa-miR-3613-3p	PAR-CLIP	22291592
MIRT445506	hsa-miR-655-5p	PAR-CLIP	22291592
MIRT445505	hsa-miR-377-5p	PAR-CLIP	22291592
MIRT445504	hsa-miR-6086	PAR-CLIP	22291592
MIRT445516	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445515	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445514	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445513	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445512	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445511	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445510	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445509	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445508	hsa-miR-329-5p	PAR-CLIP	22100165
MIRT445507	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT445506	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT445505	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT445504	hsa-miR-6086	PAR-CLIP	22100165
MIRT445516	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445515	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445514	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445513	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445512	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445511	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445510	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445509	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445508	hsa-miR-329-5p	PAR-CLIP	22100165
MIRT445507	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT445506	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT445505	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT445504	hsa-miR-6086	PAR-CLIP	22100165
MIRT910403	hsa-miR-1283	CLIP-seq
MIRT910404	hsa-miR-3153	CLIP-seq
MIRT910405	hsa-miR-34b	CLIP-seq
MIRT910406	hsa-miR-3646	CLIP-seq
MIRT910407	hsa-miR-3647-3p	CLIP-seq
MIRT910408	hsa-miR-3662	CLIP-seq
MIRT910409	hsa-miR-3663-3p	CLIP-seq
MIRT910410	hsa-miR-3691-3p	CLIP-seq
MIRT910411	hsa-miR-3915	CLIP-seq
MIRT910412	hsa-miR-3928	CLIP-seq
MIRT910413	hsa-miR-410	CLIP-seq
MIRT910414	hsa-miR-4273	CLIP-seq
MIRT910415	hsa-miR-4481	CLIP-seq
MIRT910416	hsa-miR-4487	CLIP-seq
MIRT910417	hsa-miR-4539	CLIP-seq
MIRT910418	hsa-miR-4646-5p	CLIP-seq
MIRT910419	hsa-miR-4668-5p	CLIP-seq
MIRT910420	hsa-miR-4677-5p	CLIP-seq
MIRT910421	hsa-miR-4680-5p	CLIP-seq
MIRT910422	hsa-miR-4699-3p	CLIP-seq
MIRT910423	hsa-miR-4745-5p	CLIP-seq
MIRT910424	hsa-miR-4758-5p	CLIP-seq
MIRT910425	hsa-miR-4799-5p	CLIP-seq
MIRT910426	hsa-miR-501-3p	CLIP-seq
MIRT910427	hsa-miR-502-3p	CLIP-seq
MIRT910428	hsa-miR-624	CLIP-seq
MIRT1969890	hsa-miR-1825	CLIP-seq
MIRT1969891	hsa-miR-199a-5p	CLIP-seq
MIRT1969892	hsa-miR-199b-5p	CLIP-seq
MIRT1969893	hsa-miR-224	CLIP-seq
MIRT1969894	hsa-miR-3155	CLIP-seq
MIRT1969895	hsa-miR-3155b	CLIP-seq
MIRT1969896	hsa-miR-33a	CLIP-seq
MIRT1969897	hsa-miR-33b	CLIP-seq
MIRT1969898	hsa-miR-3614-5p	CLIP-seq
MIRT1969899	hsa-miR-3913-3p	CLIP-seq
MIRT1969900	hsa-miR-3929	CLIP-seq
MIRT910413	hsa-miR-410	CLIP-seq
MIRT1969901	hsa-miR-4256	CLIP-seq
MIRT910414	hsa-miR-4273	CLIP-seq
MIRT1969902	hsa-miR-4274	CLIP-seq
MIRT1969903	hsa-miR-4299	CLIP-seq
MIRT1969904	hsa-miR-4419b	CLIP-seq
MIRT1969905	hsa-miR-4422	CLIP-seq
MIRT1969906	hsa-miR-4478	CLIP-seq
MIRT910416	hsa-miR-4487	CLIP-seq
MIRT1969907	hsa-miR-4679	CLIP-seq
MIRT1969908	hsa-miR-4803	CLIP-seq
MIRT1969909	hsa-miR-484	CLIP-seq
MIRT1969910	hsa-miR-550b	CLIP-seq
MIRT1969911	hsa-miR-570	CLIP-seq
MIRT2205899	hsa-miR-1262	CLIP-seq
MIRT1969890	hsa-miR-1825	CLIP-seq
MIRT1969891	hsa-miR-199a-5p	CLIP-seq
MIRT1969892	hsa-miR-199b-5p	CLIP-seq
MIRT2205900	hsa-miR-3138	CLIP-seq
MIRT1969894	hsa-miR-3155	CLIP-seq
MIRT1969895	hsa-miR-3155b	CLIP-seq
MIRT2205901	hsa-miR-3168	CLIP-seq
MIRT2205902	hsa-miR-3189-3p	CLIP-seq
MIRT2205903	hsa-miR-34a	CLIP-seq
MIRT2205904	hsa-miR-34c-5p	CLIP-seq
MIRT2205905	hsa-miR-3685	CLIP-seq
MIRT2205906	hsa-miR-384	CLIP-seq
MIRT1969900	hsa-miR-3929	CLIP-seq
MIRT1969902	hsa-miR-4274	CLIP-seq
MIRT2205907	hsa-miR-4277	CLIP-seq
MIRT1969904	hsa-miR-4419b	CLIP-seq
MIRT1969905	hsa-miR-4422	CLIP-seq
MIRT2205908	hsa-miR-4426	CLIP-seq
MIRT2205909	hsa-miR-4434	CLIP-seq
MIRT1969906	hsa-miR-4478	CLIP-seq
MIRT2205910	hsa-miR-4491	CLIP-seq
MIRT2205911	hsa-miR-449a	CLIP-seq
MIRT2205912	hsa-miR-449b	CLIP-seq
MIRT2205913	hsa-miR-4516	CLIP-seq
MIRT2205914	hsa-miR-4520a-3p	CLIP-seq
MIRT2205915	hsa-miR-4531	CLIP-seq
MIRT2205916	hsa-miR-4540	CLIP-seq
MIRT2205917	hsa-miR-4647	CLIP-seq
MIRT2205918	hsa-miR-4657	CLIP-seq
MIRT2205919	hsa-miR-4662b	CLIP-seq
MIRT2205920	hsa-miR-4701-3p	CLIP-seq
MIRT2205921	hsa-miR-4800-5p	CLIP-seq
MIRT1969909	hsa-miR-484	CLIP-seq
MIRT2205922	hsa-miR-516b	CLIP-seq
MIRT2205923	hsa-miR-554	CLIP-seq
MIRT1969911	hsa-miR-570	CLIP-seq
MIRT2205924	hsa-miR-576-3p	CLIP-seq
MIRT2205925	hsa-miR-635	CLIP-seq
MIRT2509141	hsa-miR-1208	CLIP-seq
MIRT2509142	hsa-miR-1243	CLIP-seq
MIRT2509143	hsa-miR-1269	CLIP-seq
MIRT2509144	hsa-miR-1269b	CLIP-seq
MIRT2509145	hsa-miR-1270	CLIP-seq
MIRT2509146	hsa-miR-1273d	CLIP-seq
MIRT2509147	hsa-miR-1305	CLIP-seq
MIRT2509148	hsa-miR-132	CLIP-seq
MIRT2509149	hsa-miR-136	CLIP-seq
MIRT2509150	hsa-miR-141	CLIP-seq
MIRT1969890	hsa-miR-1825	CLIP-seq
MIRT2509151	hsa-miR-183	CLIP-seq
MIRT2509152	hsa-miR-1910	CLIP-seq
MIRT1969891	hsa-miR-199a-5p	CLIP-seq
MIRT1969892	hsa-miR-199b-5p	CLIP-seq
MIRT2509153	hsa-miR-200a	CLIP-seq
MIRT2509154	hsa-miR-212	CLIP-seq
MIRT2509155	hsa-miR-3065-5p	CLIP-seq
MIRT2509156	hsa-miR-3122	CLIP-seq
MIRT2509157	hsa-miR-3148	CLIP-seq
MIRT910404	hsa-miR-3153	CLIP-seq
MIRT1969894	hsa-miR-3155	CLIP-seq
MIRT1969895	hsa-miR-3155b	CLIP-seq
MIRT2509158	hsa-miR-3162-3p	CLIP-seq
MIRT2509159	hsa-miR-3182	CLIP-seq
MIRT2509160	hsa-miR-335	CLIP-seq
MIRT2509161	hsa-miR-338-3p	CLIP-seq
MIRT2509162	hsa-miR-3654	CLIP-seq
MIRT2509163	hsa-miR-371-5p	CLIP-seq
MIRT2509164	hsa-miR-3909	CLIP-seq
MIRT2509165	hsa-miR-3913-5p	CLIP-seq
MIRT1969900	hsa-miR-3929	CLIP-seq
MIRT2509166	hsa-miR-3978	CLIP-seq
MIRT1969902	hsa-miR-4274	CLIP-seq
MIRT1969904	hsa-miR-4419b	CLIP-seq
MIRT1969905	hsa-miR-4422	CLIP-seq
MIRT1969906	hsa-miR-4478	CLIP-seq
MIRT2509167	hsa-miR-4517	CLIP-seq
MIRT2509168	hsa-miR-4520b-3p	CLIP-seq
MIRT2509169	hsa-miR-4529-3p	CLIP-seq
MIRT2509170	hsa-miR-4530	CLIP-seq
MIRT2509171	hsa-miR-4659a-3p	CLIP-seq
MIRT2509172	hsa-miR-4659b-3p	CLIP-seq
MIRT910419	hsa-miR-4668-5p	CLIP-seq
MIRT2509173	hsa-miR-4683	CLIP-seq
MIRT2509174	hsa-miR-4709-5p	CLIP-seq
MIRT1969909	hsa-miR-484	CLIP-seq
MIRT2509175	hsa-miR-498	CLIP-seq
MIRT2509176	hsa-miR-561	CLIP-seq
MIRT1969911	hsa-miR-570	CLIP-seq
MIRT2509177	hsa-miR-577	CLIP-seq
MIRT2509178	hsa-miR-620	CLIP-seq
MIRT2509143	hsa-miR-1269	CLIP-seq
MIRT2509144	hsa-miR-1269b	CLIP-seq
MIRT1969890	hsa-miR-1825	CLIP-seq
MIRT1969891	hsa-miR-199a-5p	CLIP-seq
MIRT1969892	hsa-miR-199b-5p	CLIP-seq
MIRT2509157	hsa-miR-3148	CLIP-seq
MIRT2509158	hsa-miR-3162-3p	CLIP-seq
MIRT2509161	hsa-miR-338-3p	CLIP-seq
MIRT2509166	hsa-miR-3978	CLIP-seq
MIRT2509168	hsa-miR-4520b-3p	CLIP-seq
MIRT2509169	hsa-miR-4529-3p	CLIP-seq
MIRT2509170	hsa-miR-4530	CLIP-seq
MIRT2509176	hsa-miR-561	CLIP-seq

Show/Hide all(18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000245	Process	Spliceosomal complex assembly	IBA	21873635
GO:0000245	Process	Spliceosomal complex assembly	IDA	12084575
GO:0000398	Process	MRNA splicing, via spliceosome	IBA	21873635
GO:0000398	Process	MRNA splicing, via spliceosome	IC	11991638
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	28076346
GO:0000398	Process	MRNA splicing, via spliceosome	TAS
GO:0000974	Component	Prp19 complex	IBA	21873635
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IDA	12084575
GO:0005515	Function	Protein binding	IPI	22365833
GO:0005634	Component	Nucleus	IDA	28076346
GO:0005654	Component	Nucleoplasm	TAS
GO:0005681	Component	Spliceosomal complex	IDA	11991638
GO:0016607	Component	Nuclear speck	IEA
GO:0071007	Component	U2-type catalytic step 2 spliceosome	IBA	21873635
GO:0071007	Component	U2-type catalytic step 2 spliceosome	IDA	28076346
GO:0071013	Component	Catalytic step 2 spliceosome	IDA	11991638
GO:0071014	Component	Post-mRNA release spliceosomal complex	IBA	21873635

MIM	HGNC	e!Ensembl
610952	15762	ENSG00000101343

Protein

UniProt ID

Q9BZJ0

Protein name

Crooked neck-like protein 1 (Crooked neck homolog) (hCrn)

Protein function

Involved in pre-mRNA splicing process (PubMed:11991638, PubMed:12084575, PubMed:28076346, PubMed:28502770). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). {ECO:0000269|PubMed:119916

PDB

5MQF , 5XJC , 5YZG , 5Z56 , 5Z57 , 5Z58 , 6FF4 , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 6ZYM , 7A5P , 7ABI , 7DVQ , 7QTT , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8I0P , 8I0R , 8I0S , 8I0T , 8I0U , 8I0V , 8I0W , 8RO2 , 9FMD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02184	HAT	256 → 288	HAT (Half-A-TPR) repeat	Repeat
PF02184	HAT	357 → 388	HAT (Half-A-TPR) repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Widely expressed (PubMed:11342225). Highly expressed in testis (PubMed:12084575). Not detected in brain and lung (PubMed:12084575). {ECO:0000269|PubMed:11342225, ECO:0000269|PubMed:12084575}.

Sequence

MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCAL
DALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQ
VPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVK
NKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRT
VISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWD
RAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVD
RARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFA
KFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQY
EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY
ALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSI
GKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRAR
AIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFEL
SSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPE
KVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLLAMAKLWKKQQQEKEDAEHHPD
EDVDESES

Sequence length

848

Interactions

View interactions

	KEGG		Reactome
	Spliceosome		mRNA Splicing - Major Pathway

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Melanoma	Cutaneous Melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340 View all (64 more)	26619011

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Basal Cell	Associate	23774526
Esophageal Neoplasms	Associate	40282339
Neoplasm Metastasis	Associate	40282339
Neoplasms	Associate	23774526, 40282339

CRNKL1 (crooked neck pre-mRNA splicing factor 1)