PRR16 (proline rich 16)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51334
Gene name Gene Name - the full gene name approved by the HGNC.
Proline rich 16
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PRR16
Synonyms (NCBI Gene) Gene synonyms aliases
DSC54, LARGEN
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q23.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(6)
miRTarBase ID miRNA Experiments Reference
MIRT1266903 hsa-miR-369-3p CLIP-seq
MIRT1266904 hsa-miR-374a CLIP-seq
MIRT1266905 hsa-miR-374b CLIP-seq
MIRT1266906 hsa-miR-4698 CLIP-seq
MIRT1266907 hsa-miR-4760-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(3)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 29892012, 32296183
GO:0045727 Process Positive regulation of translation IDA 24656129
GO:0045793 Process Positive regulation of cell size IDA 24656129
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
615931 29654 ENSG00000184838
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q569H4
Protein name Protein Largen (Mesenchymal stem cell protein DSC54) (Proline-rich protein 16)
Protein function Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those encoding proteins affecting mitochondrial functions. Increases mit
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15252 DUF4589 53 → 304 Domain of unknown function (DUF4589) Family
Sequence
Sequence length 304
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 29942085 ClinVar
Cerebral amyloid angiopathy Cerebral amyloid angiopathy GWAS
Show/Hide Text Mining Associations (4)
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 32311840
Cardiovascular Diseases Associate 24243566, 36182916
Diabetes Mellitus Type 2 Associate 36182916
Neoplasms Associate 24243566