Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51316
Gene name Gene Name - the full gene name approved by the HGNC.
Placenta associated 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PLAC8
Synonyms (NCBI Gene) Gene synonyms aliases
C15, DGIC, PNAS-144, onzin
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q21.22
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT694987 hsa-miR-1285-5p HITS-CLIP 23313552
MIRT694986 hsa-miR-939-3p HITS-CLIP 23313552
MIRT694985 hsa-miR-1285-3p HITS-CLIP 23313552
MIRT694984 hsa-miR-3187-5p HITS-CLIP 23313552
MIRT694983 hsa-miR-5189-5p HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003682 Function Chromatin binding IEA
GO:0005576 Component Extracellular region TAS
GO:0008284 Process Positive regulation of cell population proliferation IEA
GO:0009409 Process Response to cold IEA
GO:0035578 Component Azurophil granule lumen TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607515 19254 ENSG00000145287
Protein
UniProt ID Q9NZF1
Protein name Placenta-specific gene 8 protein (Protein C15)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04749 PLAC8 26 105 PLAC8 family Family
Tissue specificity TISSUE SPECIFICITY: Expressed at high levels in plasmacytoid dendritic cells. High expression in spleen, lymph nodes, peripheral blood leukocytes, and bone marrow, with lower expression in thymus, appendix, and fetal liver.
Sequence
Sequence length 115
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Systemic lupus erythematosus Systemic lupus erythematosus GWAS
Associations from Text Mining
Disease Name Relationship Type References
Acute Kidney Injury Associate 33863396
Breast Neoplasms Associate 36543379
Carcinogenesis Associate 36543379
Carcinoma Hepatocellular Associate 15826317
Carcinoma Hepatocellular Inhibit 37209778
Colorectal Neoplasms Associate 31974611
Diabetes Gestational Associate 25720387
Gastrointestinal Neoplasms Associate 31974611
Hepatitis B Stimulate 37209778
Hyperglycemia Associate 25720387