Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51310
Gene name Gene Name - the full gene name approved by the HGNC.	Solute carrier family 22 member 17
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SLC22A17
Synonyms (NCBI Gene) Gene synonyms aliases	24p3R, BOCT, BOIT, NGALR, NGALR2, NGALR3, hBOIT
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q11.2

Show/Hide all(71)

miRTarBase ID	miRNA	Experiments	Reference
MIRT675003	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT675002	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT675003	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT675002	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT1354387	hsa-miR-1257	CLIP-seq
MIRT1354388	hsa-miR-15a	CLIP-seq
MIRT1354389	hsa-miR-15b	CLIP-seq
MIRT1354390	hsa-miR-16	CLIP-seq
MIRT1354391	hsa-miR-195	CLIP-seq
MIRT1354392	hsa-miR-330-3p	CLIP-seq
MIRT1354393	hsa-miR-3926	CLIP-seq
MIRT1354394	hsa-miR-424	CLIP-seq
MIRT1354395	hsa-miR-497	CLIP-seq
MIRT1354396	hsa-miR-518a-5p	CLIP-seq
MIRT1354397	hsa-miR-527	CLIP-seq
MIRT1354398	hsa-miR-548s	CLIP-seq
MIRT2329468	hsa-miR-511	CLIP-seq
MIRT2623747	hsa-miR-1285	CLIP-seq
MIRT2623748	hsa-miR-1293	CLIP-seq
MIRT2623749	hsa-miR-147	CLIP-seq
MIRT2623750	hsa-miR-2278	CLIP-seq
MIRT2623751	hsa-miR-3064-3p	CLIP-seq
MIRT2623752	hsa-miR-3162-3p	CLIP-seq
MIRT2623753	hsa-miR-3165	CLIP-seq
MIRT2623754	hsa-miR-3173-5p	CLIP-seq
MIRT2623755	hsa-miR-3187-5p	CLIP-seq
MIRT2623756	hsa-miR-3194-5p	CLIP-seq
MIRT2623757	hsa-miR-3672	CLIP-seq
MIRT2623758	hsa-miR-3691-5p	CLIP-seq
MIRT2623759	hsa-miR-378g	CLIP-seq
MIRT2623760	hsa-miR-3911	CLIP-seq
MIRT2623761	hsa-miR-4258	CLIP-seq
MIRT2623762	hsa-miR-4264	CLIP-seq
MIRT2623763	hsa-miR-4265	CLIP-seq
MIRT2623764	hsa-miR-4296	CLIP-seq
MIRT2623765	hsa-miR-4297	CLIP-seq
MIRT2623766	hsa-miR-4314	CLIP-seq
MIRT2623767	hsa-miR-4322	CLIP-seq
MIRT2623768	hsa-miR-4417	CLIP-seq
MIRT2623769	hsa-miR-4483	CLIP-seq
MIRT2623770	hsa-miR-4486	CLIP-seq
MIRT2623771	hsa-miR-451b	CLIP-seq
MIRT2623772	hsa-miR-4640-5p	CLIP-seq
MIRT2623773	hsa-miR-4652-3p	CLIP-seq
MIRT2623774	hsa-miR-4715-3p	CLIP-seq
MIRT2623775	hsa-miR-4726-5p	CLIP-seq
MIRT2623776	hsa-miR-4764-5p	CLIP-seq
MIRT2623777	hsa-miR-4778-3p	CLIP-seq
MIRT2623778	hsa-miR-494	CLIP-seq
MIRT2623779	hsa-miR-510	CLIP-seq
MIRT2623780	hsa-miR-512-5p	CLIP-seq
MIRT2623781	hsa-miR-612	CLIP-seq
MIRT2623782	hsa-miR-622	CLIP-seq
MIRT2623783	hsa-miR-644	CLIP-seq
MIRT2623747	hsa-miR-1285	CLIP-seq
MIRT2623751	hsa-miR-3064-3p	CLIP-seq
MIRT2623752	hsa-miR-3162-3p	CLIP-seq
MIRT2623754	hsa-miR-3173-5p	CLIP-seq
MIRT2623755	hsa-miR-3187-5p	CLIP-seq
MIRT2623757	hsa-miR-3672	CLIP-seq
MIRT2623759	hsa-miR-378g	CLIP-seq
MIRT2623762	hsa-miR-4264	CLIP-seq
MIRT2623765	hsa-miR-4297	CLIP-seq
MIRT2623766	hsa-miR-4314	CLIP-seq
MIRT2623770	hsa-miR-4486	CLIP-seq
MIRT2623774	hsa-miR-4715-3p	CLIP-seq
MIRT2623777	hsa-miR-4778-3p	CLIP-seq
MIRT2623779	hsa-miR-510	CLIP-seq
MIRT2623780	hsa-miR-512-5p	CLIP-seq
MIRT2623781	hsa-miR-612	CLIP-seq
MIRT2623782	hsa-miR-622	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004888	Function	Transmembrane signaling receptor activity	ISS
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005773	Component	Vacuole	IEA
GO:0005774	Component	Vacuolar membrane	IEA
GO:0005886	Component	Plasma membrane	IDA	17253959
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006826	Process	Iron ion transport	IEA
GO:0006879	Process	Intracellular iron ion homeostasis	TAS
GO:0015891	Process	Siderophore transport	ISS
GO:0016020	Component	Membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0022857	Function	Transmembrane transporter activity	TAS
GO:0031090	Component	Organelle membrane	IDA	17253959
GO:0055085	Process	Transmembrane transport	IEA

MIM	HGNC	e!Ensembl
611461	23095	ENSG00000092096

Protein

UniProt ID

Q8WUG5

Protein name

Solute carrier family 22 member 17 (24p3 receptor) (24p3R) (Brain-type organic cation transporter) (Lipocalin-2 receptor) (Neutrophil gelatinase-associated lipocalin receptor) (NgalR)

Protein function

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentr

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00083	Sugar_tr	89 → 507	Sugar (and other) transporter	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain.

Sequence

MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL
FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL

Sequence length

538

Interactions

View interactions

	Reactome
			Iron uptake and transport

SLC22A17 (solute carrier family 22 member 17)