FKBP11 (FKBP prolyl isomerase 11)

Gene

• Entrez ID: 51303
• Gene name: FKBP prolyl isomerase 11
• Gene symbol: FKBP11
• Synonyms (NCBI Gene): FKBP19
• Chromosome: 12
• Chromosome location: 12q13.12
• Summary: FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rap

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT997156	hsa-miR-1825	CLIP-seq
MIRT997157	hsa-miR-199a-5p	CLIP-seq
MIRT997158	hsa-miR-199b-5p	CLIP-seq
MIRT997159	hsa-miR-4436b-3p	CLIP-seq
MIRT997156	hsa-miR-1825	CLIP-seq
MIRT997157	hsa-miR-199a-5p	CLIP-seq
MIRT997158	hsa-miR-199b-5p	CLIP-seq
MIRT1995693	hsa-miR-3674	CLIP-seq
MIRT997159	hsa-miR-4436b-3p	CLIP-seq
MIRT1995694	hsa-miR-4651	CLIP-seq
MIRT1995695	hsa-miR-608	CLIP-seq
MIRT1995696	hsa-miR-642b	CLIP-seq
MIRT997156	hsa-miR-1825	CLIP-seq
MIRT997157	hsa-miR-199a-5p	CLIP-seq
MIRT997158	hsa-miR-199b-5p	CLIP-seq
MIRT2229644	hsa-miR-3153	CLIP-seq
MIRT2229645	hsa-miR-3192	CLIP-seq
MIRT1995693	hsa-miR-3674	CLIP-seq
MIRT2229646	hsa-miR-4255	CLIP-seq
MIRT2229647	hsa-miR-4314	CLIP-seq
MIRT997159	hsa-miR-4436b-3p	CLIP-seq
MIRT2229648	hsa-miR-4646-5p	CLIP-seq
MIRT2229649	hsa-miR-4668-5p	CLIP-seq
MIRT1995696	hsa-miR-642b	CLIP-seq
MIRT2388011	hsa-miR-1236	CLIP-seq
MIRT2449703	hsa-miR-186	CLIP-seq
MIRT2449704	hsa-miR-3613-3p	CLIP-seq
MIRT2449705	hsa-miR-371-5p	CLIP-seq
MIRT2449706	hsa-miR-371b-5p	CLIP-seq
MIRT2449707	hsa-miR-4738-3p	CLIP-seq
MIRT2388011	hsa-miR-1236	CLIP-seq
MIRT2533568	hsa-miR-125a-5p	CLIP-seq
MIRT2533569	hsa-miR-125b	CLIP-seq
MIRT2533570	hsa-miR-3134	CLIP-seq
MIRT2533571	hsa-miR-3612	CLIP-seq
MIRT2533572	hsa-miR-3929	CLIP-seq
MIRT2533573	hsa-miR-4319	CLIP-seq
MIRT2533574	hsa-miR-4419b	CLIP-seq
MIRT2533575	hsa-miR-4443	CLIP-seq
MIRT2533576	hsa-miR-4478	CLIP-seq
MIRT2533577	hsa-miR-4534	CLIP-seq
MIRT2533578	hsa-miR-4732-3p	CLIP-seq
MIRT2533579	hsa-miR-4802-5p	CLIP-seq
MIRT2533580	hsa-miR-485-5p	CLIP-seq
MIRT2533581	hsa-miR-593	CLIP-seq
MIRT2533582	hsa-miR-650	CLIP-seq
MIRT2533583	hsa-miR-670	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IBA
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IEA
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016853	Function	Isomerase activity	IEA

Other IDs

• MIM: 610571
• HGNC: 18624
• e!Ensembl: ENSG00000134285

Protein

• UniProt ID: Q9NYL4
• Protein name: Peptidyl-prolyl cis-trans isomerase FKBP11 (PPIase FKBP11) (EC 5.2.1.8) (19 kDa FK506-binding protein) (19 kDa FKBP) (FKBP-19) (FK506-binding protein 11) (FKBP-11) (Rotamase)
• Protein function: PPIases accelerate the folding of proteins during protein synthesis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00254	FKBP_C	50 → 141	FKBP-type peptidyl-prolyl cis-trans isomerase	Domain

• Sequence:

  MTLRPSLLPLHLLLLLLLSAAVCRAEAGLETESPVRTLQVETLVEPPEPCAEPAAFGDTL
  HIHYTGSLVDGRIIDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYG
  KRGFPPSVPADAVVQYDVELIALIRANYWLKLVKGILPLVGMAMVPALLGLIGYHLYRKA
  NRPKVSKKKLKEEKRNKSKKK

• Sequence length: 201