Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51299
Gene name Gene Name - the full gene name approved by the HGNC.	Neuritin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NRN1
Synonyms (NCBI Gene) Gene synonyms aliases	NRN, dJ380B8.2
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p25.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by n

Show/Hide all(93)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028913	hsa-miR-26b-5p	Microarray	19088304
MIRT050310	hsa-miR-25-3p	CLASH	23622248
MIRT049996	hsa-miR-28-5p	CLASH	23622248
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT626909	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT626908	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT626907	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT626906	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT626905	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT1194313	hsa-miR-103a	CLIP-seq
MIRT1194314	hsa-miR-107	CLIP-seq
MIRT1194315	hsa-miR-129-5p	CLIP-seq
MIRT1194316	hsa-miR-15a	CLIP-seq
MIRT1194317	hsa-miR-15b	CLIP-seq
MIRT1194318	hsa-miR-16	CLIP-seq
MIRT1194319	hsa-miR-195	CLIP-seq
MIRT1194320	hsa-miR-3123	CLIP-seq
MIRT1194321	hsa-miR-3129-3p	CLIP-seq
MIRT1194322	hsa-miR-3133	CLIP-seq
MIRT1194323	hsa-miR-3659	CLIP-seq
MIRT1194324	hsa-miR-3919	CLIP-seq
MIRT1194325	hsa-miR-424	CLIP-seq
MIRT1194326	hsa-miR-4276	CLIP-seq
MIRT1194327	hsa-miR-4291	CLIP-seq
MIRT1194328	hsa-miR-4310	CLIP-seq
MIRT1194329	hsa-miR-4511	CLIP-seq
MIRT1194330	hsa-miR-4524	CLIP-seq
MIRT1194331	hsa-miR-4680-3p	CLIP-seq
MIRT1194332	hsa-miR-4775	CLIP-seq
MIRT1194333	hsa-miR-497	CLIP-seq
MIRT1194334	hsa-miR-503	CLIP-seq
MIRT1194335	hsa-miR-591	CLIP-seq
MIRT1194336	hsa-miR-628-5p	CLIP-seq
MIRT1194337	hsa-miR-646	CLIP-seq
MIRT2056404	hsa-miR-1284	CLIP-seq
MIRT2056405	hsa-miR-4684-5p	CLIP-seq
MIRT1194315	hsa-miR-129-5p	CLIP-seq
MIRT1194320	hsa-miR-3123	CLIP-seq
MIRT1194323	hsa-miR-3659	CLIP-seq
MIRT2284933	hsa-miR-374a	CLIP-seq
MIRT2284934	hsa-miR-374b	CLIP-seq
MIRT1194324	hsa-miR-3919	CLIP-seq
MIRT1194327	hsa-miR-4291	CLIP-seq
MIRT1194328	hsa-miR-4310	CLIP-seq
MIRT2284935	hsa-miR-4658	CLIP-seq
MIRT1194331	hsa-miR-4680-3p	CLIP-seq
MIRT1194332	hsa-miR-4775	CLIP-seq
MIRT2284936	hsa-miR-574-5p	CLIP-seq
MIRT1194336	hsa-miR-628-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007399	Process	Nervous system development	IEA
GO:0016020	Component	Membrane	IEA
GO:0032281	Component	AMPA glutamate receptor complex	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0045202	Component	Synapse	IEA
GO:0090128	Process	Regulation of synapse maturation	IEA
GO:0098552	Component	Side of membrane	IEA
GO:0098793	Component	Presynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099171	Process	Presynaptic modulation of chemical synaptic transmission	IEA
GO:1990138	Process	Neuron projection extension	IBA
GO:1990138	Process	Neuron projection extension	IEA

MIM	HGNC	e!Ensembl
607409	17972	ENSG00000124785

Protein

UniProt ID

Q9NPD7

Protein name

Neuritin

Protein function

Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15056	NRN1	31 → 117	Neuritin protein family	Domain

Sequence

MGLKLNGRYISLILAVQIAYLVQAVRAAGKCDAVFKGFSDCLLKLGDSMANYPQGLDDKT
NIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLFELCGSGNGAAGS
LLPAFPVLLVSLSAALATWLSF

Sequence length

142

Interactions

View interactions

	Reactome
			Post-translational modification: synthesis of GPI-anchored proteins

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Glioblastoma	Glioblastoma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (20)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Acute Kidney Injury	Associate	33863396
Alzheimer Disease	Associate	37024090
Bipolar Disorder	Associate	26700405
Carcinoma	Associate	37185612
Cognition Disorders	Associate	38165375
Emphysema	Associate	19723343
Hearing Loss	Associate	34530960
Hearing Loss Noise Induced	Associate	34530960
Hypoxia	Stimulate	16723126
Hypoxia Brain	Associate	16723126
Lung Neoplasms	Inhibit	33787845
Melanoma	Associate	27901477
Neoplasms	Associate	16723126
Nerve Degeneration	Inhibit	37024090
Obesity	Associate	27768648
Ovarian Diseases	Associate	31491902
Ovarian Neoplasms	Associate	31775891
Schizophrenia	Associate	26700405
Schizophrenia Spectrum and Other Psychotic Disorders	Associate	26700405
Shock Septic	Associate	33863396

NRN1 (neuritin 1)