Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51279
Gene name Gene Name - the full gene name approved by the HGNC.
Complement C1r subcomponent like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
C1RL
Synonyms (NCBI Gene) Gene synonyms aliases
C1RL1, C1RLP, C1r-LP, CLSPa
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.31
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT720565 hsa-miR-483-3p HITS-CLIP 19536157
MIRT720564 hsa-miR-5590-5p HITS-CLIP 19536157
MIRT720563 hsa-miR-4659a-5p HITS-CLIP 19536157
MIRT720562 hsa-miR-4659b-5p HITS-CLIP 19536157
MIRT720561 hsa-miR-4776-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004252 Function Serine-type endopeptidase activity IBA 21873635
GO:0005615 Component Extracellular space HDA 16502470
GO:0005615 Component Extracellular space IBA 21873635
GO:0006958 Process Complement activation, classical pathway IEA
GO:0031638 Process Zymogen activation IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608974 21265 ENSG00000139178
Protein
UniProt ID Q9NZP8
Protein name Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)
Protein function Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00431 CUB 40 154 CUB domain Domain
PF00089 Trypsin 245 479 Trypsin Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma)
Sequence
Sequence length 487
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Periodontal ehlers-danlos syndrome EHLERS-DANLOS SYNDROME, PERIODONTAL TYPE, 2, EHLERS-DANLOS SYNDROME, PERIODONTAL TYPE, 1 rs886040974, rs886040975, rs1057518645, rs760277934, rs769707492, rs1057515579, rs1057518646, rs1057518643, rs1057519026, rs1057519025, rs1057519580, rs1057519579, rs1057519578, rs1057519577, rs1057519576
View all (1 more)
Associations from Text Mining
Disease Name Relationship Type References
Endometrial Neoplasms Associate 36807337
Glioblastoma Stimulate 32993564
Glioblastoma Associate 38019838
Glioma Associate 32993564
Lymphoma B Cell Marginal Zone Associate 22170086
Lymphoma Large B Cell Diffuse Inhibit 22170086
Lymphoma Large B Cell Diffuse Associate 22170086
Lymphoma Non Hodgkin Inhibit 22170086
Lymphoma Non Hodgkin Associate 22170086
Melanoma Inhibit 37227816