Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	51253
Gene name	Mitochondrial ribosomal protein L37
Gene symbol	MRPL37
Synonyms (NCBI Gene)	L2mtL37mtMRP-L2MRP-L37MRPL2RPML2mL37
Chromosome	1
Chromosome location	1p32.3
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot

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miRTarBase ID	miRNA	Experiments	Reference
MIRT052195	hsa-let-7b-5p	CLASH	23622248
MIRT043932	hsa-miR-378a-3p	CLASH	23622248
MIRT039232	hsa-miR-454-3p	CLASH	23622248
MIRT701846	hsa-miR-670-3p	HITS-CLIP	23313552
MIRT701845	hsa-miR-499b-5p	HITS-CLIP	23313552
MIRT701844	hsa-miR-1224-3p	HITS-CLIP	23313552
MIRT701843	hsa-miR-361-3p	HITS-CLIP	23313552
MIRT701841	hsa-miR-6072	HITS-CLIP	23313552
MIRT701842	hsa-miR-6891-3p	HITS-CLIP	23313552
MIRT701840	hsa-miR-6075	HITS-CLIP	23313552
MIRT701839	hsa-miR-1307-3p	HITS-CLIP	23313552
MIRT701838	hsa-miR-4638-5p	HITS-CLIP	23313552
MIRT701837	hsa-miR-617	HITS-CLIP	23313552
MIRT701836	hsa-miR-3911	HITS-CLIP	23313552
MIRT701835	hsa-miR-644a	HITS-CLIP	23313552
MIRT701834	hsa-miR-188-3p	HITS-CLIP	23313552
MIRT701833	hsa-miR-1260a	HITS-CLIP	23313552
MIRT701832	hsa-miR-1260b	HITS-CLIP	23313552
MIRT701831	hsa-miR-3156-3p	HITS-CLIP	23313552
MIRT701830	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT701829	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT701828	hsa-miR-147a	HITS-CLIP	23313552
MIRT701827	hsa-miR-4698	HITS-CLIP	23313552
MIRT701826	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT701824	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT701825	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT701823	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT701822	hsa-miR-1913	HITS-CLIP	23313552
MIRT701821	hsa-miR-324-3p	HITS-CLIP	23313552
MIRT701820	hsa-miR-18a-3p	HITS-CLIP	23313552
MIRT701819	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT701818	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT701817	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT701816	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT701815	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT701814	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT701846	hsa-miR-670-3p	HITS-CLIP	23313552
MIRT701845	hsa-miR-499b-5p	HITS-CLIP	23313552
MIRT701844	hsa-miR-1224-3p	HITS-CLIP	23313552
MIRT701843	hsa-miR-361-3p	HITS-CLIP	23313552
MIRT701841	hsa-miR-6072	HITS-CLIP	23313552
MIRT701842	hsa-miR-6891-3p	HITS-CLIP	23313552
MIRT701840	hsa-miR-6075	HITS-CLIP	23313552
MIRT701839	hsa-miR-1307-3p	HITS-CLIP	23313552
MIRT701838	hsa-miR-4638-5p	HITS-CLIP	23313552
MIRT701837	hsa-miR-617	HITS-CLIP	23313552
MIRT701836	hsa-miR-3911	HITS-CLIP	23313552
MIRT701835	hsa-miR-644a	HITS-CLIP	23313552
MIRT701834	hsa-miR-188-3p	HITS-CLIP	23313552
MIRT701833	hsa-miR-1260a	HITS-CLIP	23313552
MIRT701832	hsa-miR-1260b	HITS-CLIP	23313552
MIRT701831	hsa-miR-3156-3p	HITS-CLIP	23313552
MIRT701830	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT701829	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT701828	hsa-miR-147a	HITS-CLIP	23313552
MIRT701827	hsa-miR-4698	HITS-CLIP	23313552
MIRT701826	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT701824	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT701825	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT701823	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT701822	hsa-miR-1913	HITS-CLIP	23313552
MIRT701821	hsa-miR-324-3p	HITS-CLIP	23313552
MIRT701820	hsa-miR-18a-3p	HITS-CLIP	23313552
MIRT701819	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT701818	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT701817	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT701816	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT701815	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT701814	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT1159270	hsa-miR-2467-5p	CLIP-seq
MIRT1159271	hsa-miR-3188	CLIP-seq
MIRT1159272	hsa-miR-3975	CLIP-seq
MIRT1159273	hsa-miR-485-5p	CLIP-seq
MIRT2274626	hsa-miR-15a	CLIP-seq
MIRT2274627	hsa-miR-15b	CLIP-seq
MIRT2274628	hsa-miR-16	CLIP-seq
MIRT2274629	hsa-miR-195	CLIP-seq
MIRT2274630	hsa-miR-1972	CLIP-seq
MIRT2274631	hsa-miR-214	CLIP-seq
MIRT2274632	hsa-miR-2278	CLIP-seq
MIRT2274633	hsa-miR-3619-5p	CLIP-seq
MIRT2274634	hsa-miR-3926	CLIP-seq
MIRT2274635	hsa-miR-424	CLIP-seq
MIRT2274636	hsa-miR-4690-5p	CLIP-seq
MIRT2274637	hsa-miR-497	CLIP-seq
MIRT2274638	hsa-miR-761	CLIP-seq
MIRT2274639	hsa-miR-891a	CLIP-seq
MIRT2573550	hsa-miR-1236	CLIP-seq
MIRT1159270	hsa-miR-2467-5p	CLIP-seq
MIRT2573551	hsa-miR-31	CLIP-seq
MIRT1159271	hsa-miR-3188	CLIP-seq
MIRT2573552	hsa-miR-3190	CLIP-seq
MIRT1159272	hsa-miR-3975	CLIP-seq
MIRT1159273	hsa-miR-485-5p	CLIP-seq
MIRT2573553	hsa-miR-7	CLIP-seq
MIRT2573550	hsa-miR-1236	CLIP-seq
MIRT1159270	hsa-miR-2467-5p	CLIP-seq
MIRT1159271	hsa-miR-3188	CLIP-seq
MIRT2573552	hsa-miR-3190	CLIP-seq
MIRT1159272	hsa-miR-3975	CLIP-seq
MIRT1159273	hsa-miR-485-5p	CLIP-seq
MIRT2573553	hsa-miR-7	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0003735	Function	Structural constituent of ribosome	NAS	11543634
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	28892042
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	27023846
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005761	Component	Mitochondrial ribosome	NAS	11543634
GO:0005762	Component	Mitochondrial large ribosomal subunit	IDA	25278503, 28892042
GO:0005762	Component	Mitochondrial large ribosomal subunit	NAS	25278503
GO:0005840	Component	Ribosome	IEA
GO:0006412	Process	Translation	IEA
GO:0006412	Process	Translation	NAS	11543634
GO:0032543	Process	Mitochondrial translation	NAS	27023846
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
611843	14034	ENSG00000116221

Q9BZE1

Protein name

Large ribosomal subunit protein mL37 (39S ribosomal protein L2, mitochondrial) (L2mt) (MRP-L2) (39S ribosomal protein L37, mitochondrial) (L37mt) (MRP-L37)

PDB

3J7Y , 3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF0 , 7OF2 , 7OF3 , 7OF4 , 7OF5 , 7OF6 , 7OF7 , 7OG4 , 7OI6 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4 , 7QH6

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07147	PDCD9	196 → 420	Mitochondrial 28S ribosomal protein S30 (PDCD9)	Family

Sequence

MALASGPARRALAGSGQLGLGGFGAPRRGAYEWGVRSTRKSEPPPLDRVYEIPGLEPITF
AGKMHFVPWLARPIFPPWDRGYKDPRFYRSPPLHEHPLYKDQACYIFHHRCRLLEGVKQA
LWLTKTKLIEGLPEKVLSLVDDPRNHIENQDECVLNVISHARLWQTTEEIPKRETYCPVI
VDNLIQLCKSQILKHPSLARRICVQNSTFSATWNRESLLLQVRGSGGARLSTKDPLPTIA
SREEIEATKNHVLETFYPISPIIDLHECNIYDVKNDTGFQEGYPYPYPHTLYLLDKANLR
PHRLQPDQLRAKMILFAFGSALAQARLLYGNDAKVLEQPVVVQSVGTDGRVFHFLVFQLN
TTDLDCNEGVKNLAWVDSDQLLYQHFWCLPVIKKRVVVEPVGPVGFKPETFRKFLALYLH
GAA

Sequence length

423

Interactions

View interactions

	Reactome
			Mitochondrial translation elongation Mitochondrial translation termination

MRPL37 (mitochondrial ribosomal protein L37)