CPA4 (carboxypeptidase A4)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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51200 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Carboxypeptidase A4 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CPA4 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CPA3 |
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Chromosome
Chromosome number
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7 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7q32.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9UI42 | |||||||||||||||
| Protein name | Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3) | |||||||||||||||
| Protein function | Metalloprotease that cleaves hydrophobic C-terminal residues with a preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val (PubMed:20385563). May function in peptide hormone and/or neuropeptide catabolism (PubMed:20385563). {ECO:0000269|PubMed:203 | |||||||||||||||
| PDB | 2BO9 , 2BOA , 2PCU , 4A94 , 4BD9 | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele. | |||||||||||||||
| Sequence | ||||||||||||||||
| Sequence length | 421 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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