CPA4 (carboxypeptidase A4)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51200 |
| Gene name | Carboxypeptidase A4 |
| Gene symbol | CPA4 |
| Synonyms (NCBI Gene) |
CPA3
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| Chromosome | 7 |
| Chromosome location | 7q32.2 |
| Summary | This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and |
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miRNA
miRNA information provided by mirtarbase database.
438
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9UI42 | |||||||||||||||
| Protein name | Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3) | |||||||||||||||
| Protein function | Metalloprotease that cleaves hydrophobic C-terminal residues with a preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val (PubMed:20385563). May function in peptide hormone and/or neuropeptide catabolism (PubMed:20385563). {ECO:0000269|PubMed:203 | |||||||||||||||
| PDB | 2BO9 , 2BOA , 2PCU , 4A94 , 4BD9 | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Fetal expression in the adrenal gland, brain, heart, intestine, kidney, liver and lung. Except for fetal brain that shows no imprinting, expression was found preferentially from the maternal allele. | |||||||||||||||
| Sequence | ||||||||||||||||
| Sequence length | 421 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
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