NIN (ninein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51199 |
| Gene name | Ninein |
| Gene symbol | NIN |
| Synonyms (NCBI Gene) |
SCKL7
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| Chromosome | 14 |
| Chromosome location | 14q22.1 |
| Summary | This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zipper |
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SNPs
SNP information provided by dbSNP.
6
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miRNA
miRNA information provided by mirtarbase database.
717
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
46
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8N4C6 | |
| Protein name | Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein) | |
| Protein function | Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15190203, PubMed:23386061). May also act as a centrosome maturation factor (PubMed:11956314). May play a role in microtubule n | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Highly expressed in heart and skeletal muscle. Isoform 1 is more expressed than isoform 5. {ECO:0000269|PubMed:11004522, ECO:0000269|PubMed:11162463}. | |
| Sequence |
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| Sequence length | 2090 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
101
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