Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51185
Gene name Gene Name - the full gene name approved by the HGNC.	Cereblon
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CRBN
Synonyms (NCBI Gene) Gene synonyms aliases	MRT2, MRT2A
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p26.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutatio

Show/Hide all(2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs78564552	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Intron variant, missense variant, coding sequence variant, 5 prime UTR variant, non coding transcript variant
rs1575094649	G>C	Likely-pathogenic	Non coding transcript variant, stop gained, coding sequence variant

Show/Hide all(253)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049014	hsa-miR-92a-3p	CLASH	23622248
MIRT908238	hsa-let-7a	CLIP-seq
MIRT908239	hsa-let-7b	CLIP-seq
MIRT908240	hsa-let-7c	CLIP-seq
MIRT908241	hsa-let-7d	CLIP-seq
MIRT908242	hsa-let-7e	CLIP-seq
MIRT908243	hsa-let-7f	CLIP-seq
MIRT908244	hsa-let-7g	CLIP-seq
MIRT908245	hsa-let-7i	CLIP-seq
MIRT908246	hsa-miR-183	CLIP-seq
MIRT908247	hsa-miR-23a	CLIP-seq
MIRT908248	hsa-miR-23b	CLIP-seq
MIRT908249	hsa-miR-23c	CLIP-seq
MIRT908250	hsa-miR-3074-3p	CLIP-seq
MIRT908251	hsa-miR-330-3p	CLIP-seq
MIRT908252	hsa-miR-361-5p	CLIP-seq
MIRT908253	hsa-miR-3658	CLIP-seq
MIRT908254	hsa-miR-3688-5p	CLIP-seq
MIRT908255	hsa-miR-3692	CLIP-seq
MIRT908256	hsa-miR-3942-3p	CLIP-seq
MIRT908257	hsa-miR-410	CLIP-seq
MIRT908258	hsa-miR-4328	CLIP-seq
MIRT908259	hsa-miR-4458	CLIP-seq
MIRT908260	hsa-miR-4470	CLIP-seq
MIRT908261	hsa-miR-4500	CLIP-seq
MIRT908262	hsa-miR-583	CLIP-seq
MIRT908263	hsa-miR-98	CLIP-seq
MIRT2205235	hsa-miR-1303	CLIP-seq
MIRT2205236	hsa-miR-2278	CLIP-seq
MIRT2205237	hsa-miR-3117-5p	CLIP-seq
MIRT2205238	hsa-miR-331-5p	CLIP-seq
MIRT2205239	hsa-miR-3910	CLIP-seq
MIRT2205240	hsa-miR-3922-5p	CLIP-seq
MIRT2205241	hsa-miR-483-3p	CLIP-seq
MIRT2205238	hsa-miR-331-5p	CLIP-seq
MIRT908238	hsa-let-7a	CLIP-seq
MIRT908239	hsa-let-7b	CLIP-seq
MIRT908240	hsa-let-7c	CLIP-seq
MIRT908241	hsa-let-7d	CLIP-seq
MIRT908242	hsa-let-7e	CLIP-seq
MIRT908243	hsa-let-7f	CLIP-seq
MIRT908244	hsa-let-7g	CLIP-seq
MIRT908245	hsa-let-7i	CLIP-seq
MIRT2508476	hsa-miR-101	CLIP-seq
MIRT2508477	hsa-miR-1206	CLIP-seq
MIRT2508478	hsa-miR-1244	CLIP-seq
MIRT2508479	hsa-miR-1262	CLIP-seq
MIRT2508480	hsa-miR-1271	CLIP-seq
MIRT2205235	hsa-miR-1303	CLIP-seq
MIRT2508481	hsa-miR-144	CLIP-seq
MIRT2508482	hsa-miR-151-3p	CLIP-seq
MIRT2508483	hsa-miR-182	CLIP-seq
MIRT908246	hsa-miR-183	CLIP-seq
MIRT2508484	hsa-miR-2052	CLIP-seq
MIRT2508485	hsa-miR-216a	CLIP-seq
MIRT2508486	hsa-miR-216b	CLIP-seq
MIRT908247	hsa-miR-23a	CLIP-seq
MIRT908248	hsa-miR-23b	CLIP-seq
MIRT908249	hsa-miR-23c	CLIP-seq
MIRT908250	hsa-miR-3074-3p	CLIP-seq
MIRT2508487	hsa-miR-30a	CLIP-seq
MIRT2508488	hsa-miR-30b	CLIP-seq
MIRT2508489	hsa-miR-30c	CLIP-seq
MIRT2508490	hsa-miR-30d	CLIP-seq
MIRT2508491	hsa-miR-30e	CLIP-seq
MIRT2205237	hsa-miR-3117-5p	CLIP-seq
MIRT2508492	hsa-miR-3140-3p	CLIP-seq
MIRT2508493	hsa-miR-3184	CLIP-seq
MIRT908251	hsa-miR-330-3p	CLIP-seq
MIRT2205238	hsa-miR-331-5p	CLIP-seq
MIRT908252	hsa-miR-361-5p	CLIP-seq
MIRT2508494	hsa-miR-3620	CLIP-seq
MIRT908253	hsa-miR-3658	CLIP-seq
MIRT2508495	hsa-miR-3671	CLIP-seq
MIRT2508496	hsa-miR-3685	CLIP-seq
MIRT908254	hsa-miR-3688-5p	CLIP-seq
MIRT2508497	hsa-miR-3691-3p	CLIP-seq
MIRT908255	hsa-miR-3692	CLIP-seq
MIRT2508498	hsa-miR-369-3p	CLIP-seq
MIRT2508499	hsa-miR-374c	CLIP-seq
MIRT2508500	hsa-miR-384	CLIP-seq
MIRT2205239	hsa-miR-3910	CLIP-seq
MIRT2508501	hsa-miR-3920	CLIP-seq
MIRT2205240	hsa-miR-3922-5p	CLIP-seq
MIRT2508502	hsa-miR-3924	CLIP-seq
MIRT2508503	hsa-miR-409-3p	CLIP-seq
MIRT2508504	hsa-miR-423-5p	CLIP-seq
MIRT2508505	hsa-miR-4257	CLIP-seq
MIRT2508506	hsa-miR-4301	CLIP-seq
MIRT2508507	hsa-miR-4305	CLIP-seq
MIRT2508508	hsa-miR-4307	CLIP-seq
MIRT908258	hsa-miR-4328	CLIP-seq
MIRT2508509	hsa-miR-4446-5p	CLIP-seq
MIRT908259	hsa-miR-4458	CLIP-seq
MIRT2508510	hsa-miR-4463	CLIP-seq
MIRT908260	hsa-miR-4470	CLIP-seq
MIRT2508511	hsa-miR-4474-5p	CLIP-seq
MIRT2508512	hsa-miR-4490	CLIP-seq
MIRT2508513	hsa-miR-4499	CLIP-seq
MIRT908261	hsa-miR-4500	CLIP-seq
MIRT2508514	hsa-miR-4642	CLIP-seq
MIRT2508515	hsa-miR-4659a-3p	CLIP-seq
MIRT2508516	hsa-miR-4659b-3p	CLIP-seq
MIRT2508517	hsa-miR-4678	CLIP-seq
MIRT2508518	hsa-miR-4701-3p	CLIP-seq
MIRT2508519	hsa-miR-4710	CLIP-seq
MIRT2508520	hsa-miR-4738-3p	CLIP-seq
MIRT2508521	hsa-miR-4755-5p	CLIP-seq
MIRT2508522	hsa-miR-4757-5p	CLIP-seq
MIRT2508523	hsa-miR-4774-5p	CLIP-seq
MIRT2508524	hsa-miR-4777-5p	CLIP-seq
MIRT2508525	hsa-miR-4780	CLIP-seq
MIRT2205241	hsa-miR-483-3p	CLIP-seq
MIRT2508526	hsa-miR-490-3p	CLIP-seq
MIRT2508527	hsa-miR-499-3p	CLIP-seq
MIRT2508528	hsa-miR-499a-3p	CLIP-seq
MIRT2508529	hsa-miR-518d-5p	CLIP-seq
MIRT2508530	hsa-miR-519b-5p	CLIP-seq
MIRT2508531	hsa-miR-519c-5p	CLIP-seq
MIRT2508532	hsa-miR-520c-5p	CLIP-seq
MIRT2508533	hsa-miR-526a	CLIP-seq
MIRT2508534	hsa-miR-548a-5p	CLIP-seq
MIRT2508535	hsa-miR-548ab	CLIP-seq
MIRT2508536	hsa-miR-548ak	CLIP-seq
MIRT2508537	hsa-miR-548b-5p	CLIP-seq
MIRT2508538	hsa-miR-548c-5p	CLIP-seq
MIRT2508539	hsa-miR-548d-5p	CLIP-seq
MIRT2508540	hsa-miR-548h	CLIP-seq
MIRT2508541	hsa-miR-548i	CLIP-seq
MIRT2508542	hsa-miR-548j	CLIP-seq
MIRT2508543	hsa-miR-548k	CLIP-seq
MIRT2508544	hsa-miR-548l	CLIP-seq
MIRT2508545	hsa-miR-548n	CLIP-seq
MIRT2508546	hsa-miR-548p	CLIP-seq
MIRT2508547	hsa-miR-548t	CLIP-seq
MIRT2508548	hsa-miR-548w	CLIP-seq
MIRT2508549	hsa-miR-548y	CLIP-seq
MIRT2508550	hsa-miR-559	CLIP-seq
MIRT2508551	hsa-miR-561	CLIP-seq
MIRT2508552	hsa-miR-562	CLIP-seq
MIRT2508553	hsa-miR-576-3p	CLIP-seq
MIRT2508554	hsa-miR-582-5p	CLIP-seq
MIRT908262	hsa-miR-583	CLIP-seq
MIRT2508555	hsa-miR-607	CLIP-seq
MIRT2508556	hsa-miR-630	CLIP-seq
MIRT2508557	hsa-miR-649	CLIP-seq
MIRT2508558	hsa-miR-655	CLIP-seq
MIRT2508559	hsa-miR-659	CLIP-seq
MIRT2508560	hsa-miR-711	CLIP-seq
MIRT2508561	hsa-miR-944	CLIP-seq
MIRT2508562	hsa-miR-96	CLIP-seq
MIRT908263	hsa-miR-98	CLIP-seq
MIRT908238	hsa-let-7a	CLIP-seq
MIRT908239	hsa-let-7b	CLIP-seq
MIRT908240	hsa-let-7c	CLIP-seq
MIRT908241	hsa-let-7d	CLIP-seq
MIRT908242	hsa-let-7e	CLIP-seq
MIRT908243	hsa-let-7f	CLIP-seq
MIRT908244	hsa-let-7g	CLIP-seq
MIRT908245	hsa-let-7i	CLIP-seq
MIRT2508476	hsa-miR-101	CLIP-seq
MIRT2508477	hsa-miR-1206	CLIP-seq
MIRT2508479	hsa-miR-1262	CLIP-seq
MIRT2508480	hsa-miR-1271	CLIP-seq
MIRT2508481	hsa-miR-144	CLIP-seq
MIRT2508482	hsa-miR-151-3p	CLIP-seq
MIRT2508483	hsa-miR-182	CLIP-seq
MIRT908246	hsa-miR-183	CLIP-seq
MIRT2508484	hsa-miR-2052	CLIP-seq
MIRT2508485	hsa-miR-216a	CLIP-seq
MIRT2508486	hsa-miR-216b	CLIP-seq
MIRT908247	hsa-miR-23a	CLIP-seq
MIRT908248	hsa-miR-23b	CLIP-seq
MIRT908249	hsa-miR-23c	CLIP-seq
MIRT908250	hsa-miR-3074-3p	CLIP-seq
MIRT2205237	hsa-miR-3117-5p	CLIP-seq
MIRT2508493	hsa-miR-3184	CLIP-seq
MIRT908251	hsa-miR-330-3p	CLIP-seq
MIRT2205238	hsa-miR-331-5p	CLIP-seq
MIRT908252	hsa-miR-361-5p	CLIP-seq
MIRT2508495	hsa-miR-3671	CLIP-seq
MIRT2508496	hsa-miR-3685	CLIP-seq
MIRT908254	hsa-miR-3688-5p	CLIP-seq
MIRT2508497	hsa-miR-3691-3p	CLIP-seq
MIRT908255	hsa-miR-3692	CLIP-seq
MIRT2508498	hsa-miR-369-3p	CLIP-seq
MIRT2508499	hsa-miR-374c	CLIP-seq
MIRT2508500	hsa-miR-384	CLIP-seq
MIRT2205239	hsa-miR-3910	CLIP-seq
MIRT2205240	hsa-miR-3922-5p	CLIP-seq
MIRT2508502	hsa-miR-3924	CLIP-seq
MIRT2508503	hsa-miR-409-3p	CLIP-seq
MIRT2508504	hsa-miR-423-5p	CLIP-seq
MIRT2508505	hsa-miR-4257	CLIP-seq
MIRT2508506	hsa-miR-4301	CLIP-seq
MIRT2508507	hsa-miR-4305	CLIP-seq
MIRT2508508	hsa-miR-4307	CLIP-seq
MIRT908258	hsa-miR-4328	CLIP-seq
MIRT2508509	hsa-miR-4446-5p	CLIP-seq
MIRT908259	hsa-miR-4458	CLIP-seq
MIRT2508510	hsa-miR-4463	CLIP-seq
MIRT908260	hsa-miR-4470	CLIP-seq
MIRT2508511	hsa-miR-4474-5p	CLIP-seq
MIRT2508512	hsa-miR-4490	CLIP-seq
MIRT2508513	hsa-miR-4499	CLIP-seq
MIRT908261	hsa-miR-4500	CLIP-seq
MIRT2508514	hsa-miR-4642	CLIP-seq
MIRT2508515	hsa-miR-4659a-3p	CLIP-seq
MIRT2508516	hsa-miR-4659b-3p	CLIP-seq
MIRT2508517	hsa-miR-4678	CLIP-seq
MIRT2508518	hsa-miR-4701-3p	CLIP-seq
MIRT2508519	hsa-miR-4710	CLIP-seq
MIRT2508520	hsa-miR-4738-3p	CLIP-seq
MIRT2508521	hsa-miR-4755-5p	CLIP-seq
MIRT2508522	hsa-miR-4757-5p	CLIP-seq
MIRT2508523	hsa-miR-4774-5p	CLIP-seq
MIRT2508524	hsa-miR-4777-5p	CLIP-seq
MIRT2508525	hsa-miR-4780	CLIP-seq
MIRT2205241	hsa-miR-483-3p	CLIP-seq
MIRT2508527	hsa-miR-499-3p	CLIP-seq
MIRT2508528	hsa-miR-499a-3p	CLIP-seq
MIRT2508529	hsa-miR-518d-5p	CLIP-seq
MIRT2508530	hsa-miR-519b-5p	CLIP-seq
MIRT2508531	hsa-miR-519c-5p	CLIP-seq
MIRT2508532	hsa-miR-520c-5p	CLIP-seq
MIRT2508533	hsa-miR-526a	CLIP-seq
MIRT2508534	hsa-miR-548a-5p	CLIP-seq
MIRT2508535	hsa-miR-548ab	CLIP-seq
MIRT2508536	hsa-miR-548ak	CLIP-seq
MIRT2508537	hsa-miR-548b-5p	CLIP-seq
MIRT2508538	hsa-miR-548c-5p	CLIP-seq
MIRT2508539	hsa-miR-548d-5p	CLIP-seq
MIRT2508540	hsa-miR-548h	CLIP-seq
MIRT2508541	hsa-miR-548i	CLIP-seq
MIRT2508542	hsa-miR-548j	CLIP-seq
MIRT2508543	hsa-miR-548k	CLIP-seq
MIRT2508544	hsa-miR-548l	CLIP-seq
MIRT2508545	hsa-miR-548n	CLIP-seq
MIRT2508547	hsa-miR-548t	CLIP-seq
MIRT2508548	hsa-miR-548w	CLIP-seq
MIRT2508549	hsa-miR-548y	CLIP-seq
MIRT2508550	hsa-miR-559	CLIP-seq
MIRT2508551	hsa-miR-561	CLIP-seq
MIRT2508553	hsa-miR-576-3p	CLIP-seq
MIRT2508554	hsa-miR-582-5p	CLIP-seq
MIRT908262	hsa-miR-583	CLIP-seq
MIRT2508555	hsa-miR-607	CLIP-seq
MIRT2508556	hsa-miR-630	CLIP-seq
MIRT2508558	hsa-miR-655	CLIP-seq
MIRT2508560	hsa-miR-711	CLIP-seq
MIRT2508561	hsa-miR-944	CLIP-seq
MIRT2508562	hsa-miR-96	CLIP-seq
MIRT908263	hsa-miR-98	CLIP-seq

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	20223979, 24292623, 25416956, 26131937, 26909574, 31515488, 32296183, 32814053, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	20223979
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	20223979
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0016020	Component	Membrane	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	IMP	20223979
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IBA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IMP	34489457
GO:0031333	Process	Negative regulation of protein-containing complex assembly	IEA
GO:0031334	Process	Positive regulation of protein-containing complex assembly	IEA
GO:0031464	Component	Cul4A-RING E3 ubiquitin ligase complex	IBA
GO:0031464	Component	Cul4A-RING E3 ubiquitin ligase complex	IDA	20223979
GO:0034766	Process	Negative regulation of monoatomic ion transmembrane transport	IEA
GO:0035641	Process	Locomotory exploration behavior	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	20223979
GO:0044325	Function	Transmembrane transporter binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0060173	Process	Limb development	IBA

MIM	HGNC	e!Ensembl
609262	30185	ENSG00000113851

Protein

UniProt ID

Q96SW2

Protein name

Protein cereblon

Protein function

Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2, ILF2 or GLUL (PubMed:26990986, PubMed:33009960). Norm

PDB

4M91 , 4TZ4 , 5FQD , 5HXB , 5V3O , 6BN7 , 6BN8 , 6BN9 , 6BNB , 6BOY , 6H0F , 6H0G , 6UML , 6XK9 , 7BQU , 7BQV , 7LPS , 7U8F , 8CVP , 8D7U , 8D7V , 8D7W , 8D7X , 8D7Y , 8D7Z , 8D80 , 8D81 , 8DEY , 8G66 , 8OIZ , 8OJH , 8RQ1 , 8RQ8 , 8RQ9 , 8RQA , 8RQC , 8TNP , 8TNQ , 8TNR , 8TZX , 8U15 , 8U16 , 8U17 , 8UH6 , 9CUO , 9DJT , 9DJX , 9DQD , 9FJX , 9GAO

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02190	LON_substr_bdg	80 → 317	ATP-dependent protease La (LON) substrate-binding domain	Family
PF03226	Yippee-Mis18	319 → 437	Yippee zinc-binding/DNA-binding /Mis18, centromere assembly	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. Highly expressed in brain. {ECO:0000269|PubMed:15557513, ECO:0000269|PubMed:17380424}.

Sequence

MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYL
GADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTF
AVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQA
KVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSW
PRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLK
IGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETL
TVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRS
ALLPTIPDTEDEISPDKVILCL

Sequence length

442

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Mental retardation	Intellectual disability, autosomal recessive 2	rs797045036, rs1575094649	N/A
Multiple myeloma	multiple myeloma	rs1575079076	N/A

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Asthma	Asthma (childhood onset)	N/A	N/A	GWAS
Bipolar Disorder	Bipolar disorder	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Restless Legs Syndrome	Restless legs syndrome	N/A	N/A	GWAS

Show/Hide Text Mining Associations (38)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Anophthalmos with limb anomalies	Associate	31964914
Attention Deficit Disorder with Hyperactivity	Associate	35052433
Auditory Perceptual Disorders	Associate	35052433
Cognition Disorders	Associate	28143899
Colorectal Neoplasms	Associate	35848491
Constipation	Associate	31115923
Diarrhea	Associate	31115923
Drug Related Side Effects and Adverse Reactions	Associate	28529032, 31300418
Erythema Nodosum	Associate	36383784
Fetal Diseases	Associate	31964914
Gastrointestinal Diseases	Associate	31115923, 36383784
Hyperbilirubinemia	Associate	31619706
Hypoalbuminemia	Associate	31619706
Infections	Associate	37058477
Intellectual Disability	Associate	15557513, 16033914, 23983124, 26024445, 28143899
Isotretinoin embryopathy like syndrome	Associate	22552008
Kidney Neoplasms	Associate	31810986
Leukemia Lymphocytic Chronic B Cell	Associate	24990888
Lupus Erythematosus Systemic	Stimulate	29945920
Lymphoma Mantle Cell	Associate	28529032
Lymphoma Primary Effusion	Associate	31300418, 33411730
Lymphoma T Cell	Associate	34936696
Mental Retardation Autosomal Recessive 4	Associate	34580524
Mental Retardation X Linked Nonsyndromic	Associate	18452889, 23983124
Mitochondrial Diseases	Associate	33408001
Multiple Myeloma	Associate	21860026, 22552008, 23233657, 23565715, 24129344, 24206017, 24687382, 24914135, 26186254, 26269456, 26430725, 27142104, 27458004, 28083618, 28643330 View all (16 more)
Myelodysplastic Syndromes	Associate	30042095
Neoplasms	Associate	28771673, 31735695, 33408001
Neoplasms	Inhibit	35579105
Neuroblastoma	Associate	34772733
Neurodevelopmental Disorders	Associate	24687382
Pancreatic Neoplasms	Associate	32893006
Peripheral Nervous System Diseases	Associate	31115923
Polyneuropathies	Associate	31115923
Prehypertension	Associate	31964914
Restless Legs Syndrome	Associate	32729462
Seizures	Associate	28143899
Syndrome	Associate	35013300

CRBN (cereblon)