Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	51182
Gene name	Heat shock protein family A (Hsp70) member 14
Gene symbol	HSPA14
Synonyms (NCBI Gene)	HSP70-4HSP70L1MSANTD7
Chromosome	10
Chromosome location	10p13

144

Show/Hide all (144)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002543	hsa-miR-373-3p	Microarray	15685193
MIRT048464	hsa-miR-100-5p	CLASH	23622248
MIRT046763	hsa-miR-222-3p	CLASH	23622248
MIRT445451	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT445449	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT445448	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT445447	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT445446	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT445445	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT445444	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT445451	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT445449	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT445448	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT445447	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT445446	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT445445	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT445444	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT645111	hsa-miR-7977	HITS-CLIP	23824327
MIRT631443	hsa-miR-532-5p	HITS-CLIP	23824327
MIRT631442	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT631441	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT631440	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT631439	hsa-miR-4489	HITS-CLIP	23824327
MIRT631438	hsa-miR-4283	HITS-CLIP	23824327
MIRT631437	hsa-miR-185-3p	HITS-CLIP	23824327
MIRT631436	hsa-miR-491-5p	HITS-CLIP	23824327
MIRT631435	hsa-miR-3151-5p	HITS-CLIP	23824327
MIRT631434	hsa-miR-4447	HITS-CLIP	23824327
MIRT631433	hsa-miR-4472	HITS-CLIP	23824327
MIRT631432	hsa-miR-6742-5p	HITS-CLIP	23824327
MIRT631431	hsa-miR-4633-5p	HITS-CLIP	23824327
MIRT631430	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT445451	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT445449	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT445448	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT445447	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT445446	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT445445	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT445444	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT445443	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT445451	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445449	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445448	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445447	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445446	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445445	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445444	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445443	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445442	hsa-miR-3163	PAR-CLIP	22100165
MIRT445441	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT445440	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT445439	hsa-miR-6083	PAR-CLIP	22100165
MIRT445451	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445449	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445448	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445447	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445446	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445445	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445444	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445443	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445442	hsa-miR-3163	PAR-CLIP	22100165
MIRT445441	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT445440	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT445439	hsa-miR-6083	PAR-CLIP	22100165
MIRT445451	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT445449	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT445448	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT445447	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT445446	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT445445	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT445444	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT445451	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT445449	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT445448	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT445447	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT445446	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT445445	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT445444	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT645111	hsa-miR-7977	HITS-CLIP	23824327
MIRT631443	hsa-miR-532-5p	HITS-CLIP	23824327
MIRT631442	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT631441	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT631440	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT631439	hsa-miR-4489	HITS-CLIP	23824327
MIRT631438	hsa-miR-4283	HITS-CLIP	23824327
MIRT631437	hsa-miR-185-3p	HITS-CLIP	23824327
MIRT631436	hsa-miR-491-5p	HITS-CLIP	23824327
MIRT631435	hsa-miR-3151-5p	HITS-CLIP	23824327
MIRT631434	hsa-miR-4447	HITS-CLIP	23824327
MIRT631433	hsa-miR-4472	HITS-CLIP	23824327
MIRT631432	hsa-miR-6742-5p	HITS-CLIP	23824327
MIRT631431	hsa-miR-4633-5p	HITS-CLIP	23824327
MIRT631430	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT445451	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT445449	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT445448	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT445447	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT445446	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT445445	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT445444	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT445443	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT445451	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445449	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445448	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445447	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445446	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445445	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445444	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445443	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445442	hsa-miR-3163	PAR-CLIP	22100165
MIRT445441	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT445440	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT445439	hsa-miR-6083	PAR-CLIP	22100165
MIRT445451	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445449	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445448	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445447	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445446	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445445	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445444	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445443	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445442	hsa-miR-3163	PAR-CLIP	22100165
MIRT445441	hsa-miR-410-3p	PAR-CLIP	22100165
MIRT445440	hsa-miR-190a-3p	PAR-CLIP	22100165
MIRT445439	hsa-miR-6083	PAR-CLIP	22100165
MIRT1056061	hsa-miR-3591-3p	CLIP-seq
MIRT1056062	hsa-miR-374c	CLIP-seq
MIRT1056063	hsa-miR-4731-3p	CLIP-seq
MIRT1056064	hsa-miR-4789-5p	CLIP-seq
MIRT1056065	hsa-miR-4801	CLIP-seq
MIRT1056066	hsa-miR-548aa	CLIP-seq
MIRT1056067	hsa-miR-548l	CLIP-seq
MIRT1056068	hsa-miR-655	CLIP-seq
MIRT1056061	hsa-miR-3591-3p	CLIP-seq
MIRT1056062	hsa-miR-374c	CLIP-seq
MIRT2012885	hsa-miR-409-3p	CLIP-seq
MIRT1056063	hsa-miR-4731-3p	CLIP-seq
MIRT1056064	hsa-miR-4789-5p	CLIP-seq
MIRT1056065	hsa-miR-4801	CLIP-seq
MIRT1056066	hsa-miR-548aa	CLIP-seq
MIRT1056067	hsa-miR-548l	CLIP-seq
MIRT2012886	hsa-miR-548n	CLIP-seq
MIRT2012887	hsa-miR-582-5p	CLIP-seq
MIRT1056068	hsa-miR-655	CLIP-seq

Show/Hide all (20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0005515	Function	Protein binding	IPI	16002468, 28514442, 33961781, 35271311
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	16002468, 21231916
GO:0005829	Component	Cytosol	IEA
GO:0005840	Component	Ribosome	IBA
GO:0005840	Component	Ribosome	IDA	16002468
GO:0005886	Component	Plasma membrane	IBA
GO:0006457	Process	Protein folding	IBA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016887	Function	ATP hydrolysis activity	IBA
GO:0031072	Function	Heat shock protein binding	IBA
GO:0042026	Process	Protein refolding	IBA
GO:0044183	Function	Protein folding chaperone	IBA
GO:0051083	Process	'de novo' cotranslational protein folding	TAS	16002468
GO:0140662	Function	ATP-dependent protein folding chaperone	IEA

MIM	HGNC	e!Ensembl
610369	29526	ENSG00000187522

Q0VDF9

Protein name

Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) (Heat shock protein family A member 14)

Protein function

Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase ac

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00012	HSP70	3 → 509	Hsp70 protein	Family

Sequence

MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI
SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLI
FSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAY
GIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLA
SEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARF
ELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNS
IPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGT
PLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL
TMKRDGSLHVTCTDQETGKCEAISIEIAS

Sequence length

509

Interactions

View interactions

	Reactome
			Regulation of HSF1-mediated heat shock response

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
MOUTH DISEASES	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Stimulate	39828281	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Associate	39828281	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	25798051	★★★★★ ★☆☆☆☆ Found in Text Mining only
HIV Infections	Associate	36845091	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Associate	33225964	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	25798051, 27129500	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Associate	31744495	★★★★★ ★☆☆☆☆ Found in Text Mining only

HSPA14 (heat shock protein family A (Hsp70) member 14)