Gene Gene information from NCBI Gene database.
Entrez ID 51164
Gene name Dynactin subunit 4
Gene symbol DCTN4
Synonyms (NCBI Gene)
DYN4P62
Chromosome 5
Chromosome location 5q33.1
miRNA miRNA information provided by mirtarbase database.
957
miRTarBase ID miRNA Experiments Reference
MIRT021605 hsa-miR-142-3p Microarray 17612493
MIRT028163 hsa-miR-93-5p Sequencing 20371350
MIRT045463 hsa-miR-149-5p CLASH 23622248
MIRT043893 hsa-miR-378a-3p CLASH 23622248
MIRT042076 hsa-miR-484 CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
GO ID Ontology Definition Evidence Reference
GO:0000776 Component Kinetochore IEA
GO:0000922 Component Spindle pole IEA
GO:0001725 Component Stress fiber IEA
GO:0005515 Function Protein binding IPI 16554302, 21516116, 25416956, 26871637, 32296183, 32814053
GO:0005634 Component Nucleus TAS 10671518
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614758 15518 ENSG00000132912
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UJW0
Protein name Dynactin subunit 4 (Dyn4) (Dynactin subunit p62)
Protein function Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05502 Dynactin_p62 23 181 Dynactin p62 family Family
PF05502 Dynactin_p62 141 375 Dynactin p62 family Family
Sequence
MASLLQSDRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPS
AEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRD
VGMADKSVASGGWQEPENPH
TQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSD
K
YGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLT
EVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQL
VAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVV
PPKELVLAGKDAAAE
YDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFK
MKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP
Sequence length 460
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Motor proteins
Vasopressin-regulated water reabsorption
Amyotrophic lateral sclerosis
Huntington disease
Pathways of neurodegeneration - multiple diseases
Salmonella infection
  MHC class II antigen presentation
HSP90 chaperone cycle for steroid hormone receptors (SHR)
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic