Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	51150
Gene name	Stromal cell derived factor 4
Gene symbol	SDF4
Synonyms (NCBI Gene)	Cab45SDF-4
Chromosome	1
Chromosome location	1p36.33
Summary	This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium de

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miRTarBase ID	miRNA	Experiments	Reference
MIRT043980	hsa-miR-378a-5p	CLASH	23622248
MIRT042088	hsa-miR-484	CLASH	23622248
MIRT461032	hsa-miR-9500	PAR-CLIP	23592263
MIRT461031	hsa-miR-6134	PAR-CLIP	23592263
MIRT461030	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT461029	hsa-miR-4767	PAR-CLIP	23592263
MIRT461028	hsa-miR-6077	PAR-CLIP	23592263
MIRT461027	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT461025	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT461026	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT461024	hsa-miR-663a	PAR-CLIP	23592263
MIRT461023	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT461022	hsa-miR-615-5p	PAR-CLIP	23592263
MIRT461021	hsa-miR-7704	PAR-CLIP	23592263
MIRT461020	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT461019	hsa-miR-6742-5p	PAR-CLIP	23592263
MIRT461018	hsa-miR-4497	PAR-CLIP	23592263
MIRT439695	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439695	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT461032	hsa-miR-9500	PAR-CLIP	23592263
MIRT461031	hsa-miR-6134	PAR-CLIP	23592263
MIRT461030	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT461029	hsa-miR-4767	PAR-CLIP	23592263
MIRT461028	hsa-miR-6077	PAR-CLIP	23592263
MIRT461027	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT461025	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT461026	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT461024	hsa-miR-663a	PAR-CLIP	23592263
MIRT461023	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT461022	hsa-miR-615-5p	PAR-CLIP	23592263
MIRT461021	hsa-miR-7704	PAR-CLIP	23592263
MIRT461020	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT461019	hsa-miR-6742-5p	PAR-CLIP	23592263
MIRT461018	hsa-miR-4497	PAR-CLIP	23592263
MIRT1331713	hsa-miR-1273f	CLIP-seq
MIRT1331714	hsa-miR-1293	CLIP-seq
MIRT1331715	hsa-miR-143	CLIP-seq
MIRT1331716	hsa-miR-1538	CLIP-seq
MIRT1331717	hsa-miR-33a	CLIP-seq
MIRT1331718	hsa-miR-33b	CLIP-seq
MIRT1331719	hsa-miR-3649	CLIP-seq
MIRT1331720	hsa-miR-3661	CLIP-seq
MIRT1331721	hsa-miR-4330	CLIP-seq
MIRT1331722	hsa-miR-4483	CLIP-seq
MIRT1331723	hsa-miR-4533	CLIP-seq
MIRT1331724	hsa-miR-4690-3p	CLIP-seq
MIRT1331725	hsa-miR-4708-5p	CLIP-seq
MIRT1331726	hsa-miR-4734	CLIP-seq
MIRT1331727	hsa-miR-4745-3p	CLIP-seq
MIRT1331728	hsa-miR-4747-3p	CLIP-seq
MIRT1331729	hsa-miR-4747-5p	CLIP-seq
MIRT1331730	hsa-miR-4755-3p	CLIP-seq
MIRT1331731	hsa-miR-4770	CLIP-seq
MIRT1331732	hsa-miR-492	CLIP-seq
MIRT1331733	hsa-miR-631	CLIP-seq
MIRT1331734	hsa-miR-744	CLIP-seq
MIRT1331735	hsa-miR-941	CLIP-seq
MIRT2098030	hsa-miR-1343	CLIP-seq
MIRT1331716	hsa-miR-1538	CLIP-seq
MIRT2098031	hsa-miR-331-3p	CLIP-seq
MIRT1331723	hsa-miR-4533	CLIP-seq
MIRT2098032	hsa-miR-4539	CLIP-seq
MIRT1331727	hsa-miR-4745-3p	CLIP-seq
MIRT1331728	hsa-miR-4747-3p	CLIP-seq
MIRT1331729	hsa-miR-4747-5p	CLIP-seq
MIRT1331730	hsa-miR-4755-3p	CLIP-seq
MIRT2098033	hsa-miR-4794	CLIP-seq
MIRT1331735	hsa-miR-941	CLIP-seq
MIRT2098030	hsa-miR-1343	CLIP-seq
MIRT2098031	hsa-miR-331-3p	CLIP-seq
MIRT2098032	hsa-miR-4539	CLIP-seq
MIRT2098030	hsa-miR-1343	CLIP-seq
MIRT2098031	hsa-miR-331-3p	CLIP-seq
MIRT2098032	hsa-miR-4539	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IDA	17442889
GO:0005509	Function	Calcium ion binding	IEA
GO:0005509	Function	Calcium ion binding	ISS
GO:0005515	Function	Protein binding	IPI	17442889, 32814053
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS	17442889
GO:0005770	Component	Late endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005796	Component	Golgi lumen	IEA
GO:0005796	Component	Golgi lumen	ISS
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS	17442889
GO:0006887	Process	Exocytosis	IEA
GO:0009650	Process	UV protection	ISS	18355758
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0017156	Process	Calcium-ion regulated exocytosis	IBA
GO:0017156	Process	Calcium-ion regulated exocytosis	ISS	17442889
GO:0021549	Process	Cerebellum development	ISS	18355758
GO:0032059	Component	Bleb	IEA
GO:0042802	Function	Identical protein binding	ISS	17442889
GO:0042995	Component	Cell projection	IEA
GO:0045444	Process	Fat cell differentiation	ISS
GO:0045471	Process	Response to ethanol	ISS	18355758
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	19199708
GO:0070625	Process	Zymogen granule exocytosis	ISS	17442889
GO:0099558	Process	Maintenance of synapse structure	IGI	33667157

MIM	HGNC	e!Ensembl
614282	24188	ENSG00000078808

Q9BRK5

Protein name

45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)

Protein function

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. ; Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13499	EF-hand_7	90 → 167	EF-hand domain pair	Domain
PF13202	EF-hand_5	288 → 307	EF hand	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Isoform 5 is expressed in pancreas. {ECO:0000269|PubMed:17442889}.

Sequence

MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPD
HLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISA
KEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADA
IRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKE
IVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTA
EELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHE
EF

Sequence length

362

Interactions

View interactions

SDF4 (stromal cell derived factor 4)