Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51150
Gene name Gene Name - the full gene name approved by the HGNC.	Stromal cell derived factor 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SDF4
Synonyms (NCBI Gene) Gene synonyms aliases	Cab45, SDF-4
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p36.33
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium de

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miRTarBase ID	miRNA	Experiments	Reference
MIRT043980	hsa-miR-378a-5p	CLASH	23622248
MIRT042088	hsa-miR-484	CLASH	23622248
MIRT461032	hsa-miR-9500	PAR-CLIP	23592263
MIRT461031	hsa-miR-6134	PAR-CLIP	23592263
MIRT461030	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT461029	hsa-miR-4767	PAR-CLIP	23592263
MIRT461028	hsa-miR-6077	PAR-CLIP	23592263
MIRT461027	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT461025	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT461026	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT461024	hsa-miR-663a	PAR-CLIP	23592263
MIRT461023	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT461022	hsa-miR-615-5p	PAR-CLIP	23592263
MIRT461021	hsa-miR-7704	PAR-CLIP	23592263
MIRT461020	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT461019	hsa-miR-6742-5p	PAR-CLIP	23592263
MIRT461018	hsa-miR-4497	PAR-CLIP	23592263
MIRT439695	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439695	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT461032	hsa-miR-9500	PAR-CLIP	23592263
MIRT461031	hsa-miR-6134	PAR-CLIP	23592263
MIRT461030	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT461029	hsa-miR-4767	PAR-CLIP	23592263
MIRT461028	hsa-miR-6077	PAR-CLIP	23592263
MIRT461027	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT461025	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT461026	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT461024	hsa-miR-663a	PAR-CLIP	23592263
MIRT461023	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT461022	hsa-miR-615-5p	PAR-CLIP	23592263
MIRT461021	hsa-miR-7704	PAR-CLIP	23592263
MIRT461020	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT461019	hsa-miR-6742-5p	PAR-CLIP	23592263
MIRT461018	hsa-miR-4497	PAR-CLIP	23592263
MIRT1331713	hsa-miR-1273f	CLIP-seq
MIRT1331714	hsa-miR-1293	CLIP-seq
MIRT1331715	hsa-miR-143	CLIP-seq
MIRT1331716	hsa-miR-1538	CLIP-seq
MIRT1331717	hsa-miR-33a	CLIP-seq
MIRT1331718	hsa-miR-33b	CLIP-seq
MIRT1331719	hsa-miR-3649	CLIP-seq
MIRT1331720	hsa-miR-3661	CLIP-seq
MIRT1331721	hsa-miR-4330	CLIP-seq
MIRT1331722	hsa-miR-4483	CLIP-seq
MIRT1331723	hsa-miR-4533	CLIP-seq
MIRT1331724	hsa-miR-4690-3p	CLIP-seq
MIRT1331725	hsa-miR-4708-5p	CLIP-seq
MIRT1331726	hsa-miR-4734	CLIP-seq
MIRT1331727	hsa-miR-4745-3p	CLIP-seq
MIRT1331728	hsa-miR-4747-3p	CLIP-seq
MIRT1331729	hsa-miR-4747-5p	CLIP-seq
MIRT1331730	hsa-miR-4755-3p	CLIP-seq
MIRT1331731	hsa-miR-4770	CLIP-seq
MIRT1331732	hsa-miR-492	CLIP-seq
MIRT1331733	hsa-miR-631	CLIP-seq
MIRT1331734	hsa-miR-744	CLIP-seq
MIRT1331735	hsa-miR-941	CLIP-seq
MIRT2098030	hsa-miR-1343	CLIP-seq
MIRT1331716	hsa-miR-1538	CLIP-seq
MIRT2098031	hsa-miR-331-3p	CLIP-seq
MIRT1331723	hsa-miR-4533	CLIP-seq
MIRT2098032	hsa-miR-4539	CLIP-seq
MIRT1331727	hsa-miR-4745-3p	CLIP-seq
MIRT1331728	hsa-miR-4747-3p	CLIP-seq
MIRT1331729	hsa-miR-4747-5p	CLIP-seq
MIRT1331730	hsa-miR-4755-3p	CLIP-seq
MIRT2098033	hsa-miR-4794	CLIP-seq
MIRT1331735	hsa-miR-941	CLIP-seq
MIRT2098030	hsa-miR-1343	CLIP-seq
MIRT2098031	hsa-miR-331-3p	CLIP-seq
MIRT2098032	hsa-miR-4539	CLIP-seq
MIRT2098030	hsa-miR-1343	CLIP-seq
MIRT2098031	hsa-miR-331-3p	CLIP-seq
MIRT2098032	hsa-miR-4539	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IBA	21873635
GO:0005509	Function	Calcium ion binding	ISS
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005737	Component	Cytoplasm	ISS	17442889
GO:0005770	Component	Late endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	IBA	21873635
GO:0005794	Component	Golgi apparatus	IDA
GO:0005796	Component	Golgi lumen	ISS
GO:0005886	Component	Plasma membrane	ISS	17442889
GO:0009650	Process	UV protection	ISS	18355758
GO:0016020	Component	Membrane	HDA	19946888
GO:0017156	Process	Calcium-ion regulated exocytosis	IBA	21873635
GO:0017156	Process	Calcium-ion regulated exocytosis	ISS	17442889
GO:0021549	Process	Cerebellum development	ISS	18355758
GO:0032059	Component	Bleb	IEA
GO:0042802	Function	Identical protein binding	ISS	17442889
GO:0045444	Process	Fat cell differentiation	ISS
GO:0045471	Process	Response to ethanol	ISS	18355758
GO:0070062	Component	Extracellular exosome	HDA	19199708
GO:0070625	Process	Zymogen granule exocytosis	ISS	17442889

MIM	HGNC	e!Ensembl
614282	24188	ENSG00000078808

Protein

UniProt ID

Q9BRK5

Protein name

45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)

Protein function

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. ; Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13499	EF-hand_7	90 → 167	EF-hand domain pair	Domain
PF13202	EF-hand_5	288 → 307	EF hand	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Isoform 5 is expressed in pancreas. {ECO:0000269|PubMed:17442889}.

Sequence

MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPD
HLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISA
KEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADA
IRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKE
IVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTA
EELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHE
EF

Sequence length

362

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	21743468

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	19513569
Calcinosis Cutis	Inhibit	19513569
Death	Inhibit	19513569
Nasopharyngeal Carcinoma	Associate	36606322
Neoplasms	Associate	27194945, 36606322
Pancreatic Neoplasms	Associate	16215274

SDF4 (stromal cell derived factor 4)