Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51149
Gene name Gene Name - the full gene name approved by the HGNC.	MRN complex interacting protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MRNIP
Synonyms (NCBI Gene) Gene synonyms aliases	C5orf45
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q35.3

Show/Hide all(97)

miRTarBase ID	miRNA	Experiments	Reference
MIRT690227	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT636899	hsa-miR-216a-5p	HITS-CLIP	23313552
MIRT690226	hsa-miR-216b-5p	HITS-CLIP	23313552
MIRT690225	hsa-miR-3929	HITS-CLIP	23313552
MIRT690224	hsa-miR-4419b	HITS-CLIP	23313552
MIRT690223	hsa-miR-4478	HITS-CLIP	23313552
MIRT690222	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT690221	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT690220	hsa-miR-5690	HITS-CLIP	23313552
MIRT690219	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT636892	hsa-miR-6787-3p	HITS-CLIP	23313552
MIRT690218	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT690217	hsa-miR-1827	HITS-CLIP	23313552
MIRT690216	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT690215	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT690214	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT690213	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT690212	hsa-miR-665	HITS-CLIP	23313552
MIRT690211	hsa-miR-3714	HITS-CLIP	23313552
MIRT690210	hsa-miR-383-5p	HITS-CLIP	23313552
MIRT690209	hsa-miR-5694	HITS-CLIP	23313552
MIRT690208	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT690207	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT690206	hsa-miR-940	HITS-CLIP	23313552
MIRT690205	hsa-miR-3927-3p	HITS-CLIP	23313552
MIRT690204	hsa-miR-6831-5p	HITS-CLIP	23313552
MIRT690203	hsa-miR-3622a-3p	HITS-CLIP	23313552
MIRT690202	hsa-miR-3622b-3p	HITS-CLIP	23313552
MIRT690201	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT690200	hsa-miR-4736	HITS-CLIP	23313552
MIRT690199	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT690198	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT690197	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT690196	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT690195	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT690194	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT690193	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT690192	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT690191	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT690190	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT690189	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT690188	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT690187	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT690186	hsa-miR-3689c	HITS-CLIP	23313552
MIRT690185	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT690184	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT690183	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT690182	hsa-miR-3122	HITS-CLIP	23313552
MIRT690181	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT690180	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT690179	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT617514	hsa-miR-4282	HITS-CLIP	23824327
MIRT617513	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617512	hsa-miR-1267	HITS-CLIP	23824327
MIRT617511	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT617510	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT617509	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT617508	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT617507	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT617506	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT636899	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT636898	hsa-miR-532-5p	HITS-CLIP	23824327
MIRT636897	hsa-miR-4714-3p	HITS-CLIP	23824327
MIRT636896	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT636895	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT636894	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT636892	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT636893	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT636891	hsa-miR-4633-5p	HITS-CLIP	23824327
MIRT617514	hsa-miR-4282	HITS-CLIP	23824327
MIRT617513	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617512	hsa-miR-1267	HITS-CLIP	23824327
MIRT617511	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT617510	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT617509	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT617508	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT617507	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT617506	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT617514	hsa-miR-4282	HITS-CLIP	23824327
MIRT617513	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617512	hsa-miR-1267	HITS-CLIP	23824327
MIRT617511	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT617510	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT617509	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT617508	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT617507	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT617506	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT514831	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT514830	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT514829	hsa-miR-3934-5p	PAR-CLIP	23446348
MIRT514828	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT514827	hsa-miR-4252	PAR-CLIP	23446348
MIRT514826	hsa-miR-668-5p	PAR-CLIP	23446348
MIRT514825	hsa-miR-6720-3p	PAR-CLIP	23446348
MIRT514824	hsa-miR-5095	PAR-CLIP	23446348
MIRT514823	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT514822	hsa-miR-6807-5p	PAR-CLIP	23446348

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003682	Function	Chromatin binding	IBA
GO:0003682	Function	Chromatin binding	IDA	27568553
GO:0005515	Function	Protein binding	IPI	27568553, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	27568553
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA	27568553
GO:0005654	Component	Nucleoplasm	IEA
GO:0006281	Process	DNA repair	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	IMP	27568553
GO:0007095	Process	Mitotic G2 DNA damage checkpoint signaling	IBA
GO:0007095	Process	Mitotic G2 DNA damage checkpoint signaling	IMP	27568553
GO:0010212	Process	Response to ionizing radiation	IMP	27568553
GO:0030870	Component	Mre11 complex	IDA	27568553
GO:0045860	Process	Positive regulation of protein kinase activity	IMP	27568553
GO:0071168	Process	Protein localization to chromatin	IDA	27568553
GO:1905168	Process	Positive regulation of double-strand break repair via homologous recombination	IMP	27568553
GO:2001032	Process	Regulation of double-strand break repair via nonhomologous end joining	IMP	27568553

MIM	HGNC	e!Ensembl
617154	30817	ENSG00000161010

Protein

UniProt ID

Q6NTE8

Protein name

MRN complex-interacting protein (MRN-interacting protein)

Protein function

Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex (PubMed:27568553). Promotes chromatin loading and activity of the MRN complex to facilitate s

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15749	MRNIP	9 → 110	MRN-interacting protein	Family

Sequence

MASLQRSRVLRCCSCRLFQAHQVKKSVKWTCKACGEKQSFLQAYGEGSGADCRRHVQKLN
LLQGQVSELPLRSLEETVSASEEENVGHQQAGNVKQQEKSQPSESRWLKYLEKDSQELEL
EGTGVCFSKQPSSKMEEPGPRFSQDLPRKRKWSRSTVQPPCSRGVQDSGGSEVAWGPQKG
QAGLTWKVKQGSSPCLQENSADCSAGELRGPGKELWSPIQQVTATSSKWAQFVLPPRKSS
HVDSEQPRSLQRDPRPAGPAQAKQGTPRAQASREGLSRPTAAVQLPRATHPVTSGSERPC
GKTSWDARTPWAEGGPLVLEAQNPRPTRLCDLFITGEDFDDDV

Sequence length

343

Interactions

View interactions

MRNIP (MRN complex interacting protein)