SAR1B (secretion associated Ras related GTPase 1B)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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51128 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Secretion associated Ras related GTPase 1B |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SAR1B |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ANDD, CMRD, GTBPB, SARA2 |
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Chromosome
Chromosome number
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5 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q31.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9Y6B6 | ||||||||||
| Protein name | Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B) | ||||||||||
| Protein function | Small GTPase that cycles between an active GTP-bound and an inactive GDP-bound state and mainly functions in vesicle-mediated endoplasmic reticulum (ER) to Golgi transport. The active GTP-bound form inserts into the endoplasmic reticulum membran | ||||||||||
| PDB | 8E0A , 8E0B , 8E0C , 8E0D | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in many tissues including small intestine, liver, muscle and brain. {ECO:0000269|PubMed:12692552}. | ||||||||||
| Sequence |
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| Sequence length | 198 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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