Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51108
Gene name Gene Name - the full gene name approved by the HGNC.
Methyltransferase 9, His-X-His N1(pi)-histidine
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
METTL9
Synonyms (NCBI Gene) Gene synonyms aliases
CGI-81, DREV, DREV1, PAP1, hMETTL9
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p12.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024304 hsa-miR-215-5p Microarray 19074876
MIRT026436 hsa-miR-192-5p Microarray 19074876
MIRT029221 hsa-miR-26b-5p Microarray 19088304
MIRT1145133 hsa-miR-103a CLIP-seq
MIRT1145134 hsa-miR-107 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21784977, 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609388 24586 ENSG00000197006
Protein
UniProt ID Q9H1A3
Protein name Protein-L-histidine N-pros-methyltransferase (EC 2.1.1.-) (DORA reverse strand protein) (DREV) (DREV1) (Methyltransferase-like protein 9) (hMETTL9)
Protein function Protein-histidine N-methyltransferase that specifically catalyzes 1-methylhistidine (pros-methylhistidine) methylation of target proteins (PubMed:33563959, PubMed:34562450, PubMed:37015930, PubMed:37398635). Specifically methylates the second Hi
PDB 7Y9C , 7YF2 , 7YF3 , 7YF4 , 8GZE , 8GZF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05219 DREV 56 317 DREV methyltransferase Family
Sequence
Sequence length 318
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 30718901, 29662059 ClinVar
Mental Depression Mental Depression GWAS
Schizophrenia Schizophrenia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Acquired Immunodeficiency Syndrome Associate 7853493
Cytomegalovirus Infections Associate 7853493
Glioblastoma Associate 37061119