Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51094
Gene name Gene Name - the full gene name approved by the HGNC.	Adiponectin receptor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ADIPOR1
Synonyms (NCBI Gene) Gene synonyms aliases	ACDCR1, CGI-45, CGI45, PAQR1, TESBP1A
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q32.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase

Show/Hide all(259)

miRTarBase ID	miRNA	Experiments	Reference
MIRT048047	hsa-miR-197-3p	CLASH	23622248
MIRT441261	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT441261	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT768907	hsa-miR-1254	CLIP-seq
MIRT768908	hsa-miR-127-5p	CLIP-seq
MIRT768909	hsa-miR-1278	CLIP-seq
MIRT768910	hsa-miR-1294	CLIP-seq
MIRT768911	hsa-miR-221	CLIP-seq
MIRT768912	hsa-miR-222	CLIP-seq
MIRT768913	hsa-miR-3116	CLIP-seq
MIRT768914	hsa-miR-3119	CLIP-seq
MIRT768915	hsa-miR-3184	CLIP-seq
MIRT768916	hsa-miR-3649	CLIP-seq
MIRT768917	hsa-miR-3690	CLIP-seq
MIRT768918	hsa-miR-3973	CLIP-seq
MIRT768919	hsa-miR-410	CLIP-seq
MIRT768920	hsa-miR-423-5p	CLIP-seq
MIRT768921	hsa-miR-4316	CLIP-seq
MIRT768922	hsa-miR-4426	CLIP-seq
MIRT768923	hsa-miR-4635	CLIP-seq
MIRT768924	hsa-miR-4638-3p	CLIP-seq
MIRT768925	hsa-miR-4647	CLIP-seq
MIRT768926	hsa-miR-4662b	CLIP-seq
MIRT768927	hsa-miR-4677-3p	CLIP-seq
MIRT768928	hsa-miR-4679	CLIP-seq
MIRT768929	hsa-miR-4786-3p	CLIP-seq
MIRT768930	hsa-miR-520g	CLIP-seq
MIRT768931	hsa-miR-520h	CLIP-seq
MIRT768932	hsa-miR-532-5p	CLIP-seq
MIRT768933	hsa-miR-548k	CLIP-seq
MIRT768934	hsa-miR-548n	CLIP-seq
MIRT768935	hsa-miR-548t	CLIP-seq
MIRT768936	hsa-miR-548v	CLIP-seq
MIRT768937	hsa-miR-593	CLIP-seq
MIRT768938	hsa-miR-595	CLIP-seq
MIRT768939	hsa-miR-603	CLIP-seq
MIRT768940	hsa-miR-607	CLIP-seq
MIRT768941	hsa-miR-648	CLIP-seq
MIRT768907	hsa-miR-1254	CLIP-seq
MIRT768908	hsa-miR-127-5p	CLIP-seq
MIRT768909	hsa-miR-1278	CLIP-seq
MIRT768910	hsa-miR-1294	CLIP-seq
MIRT768913	hsa-miR-3116	CLIP-seq
MIRT768942	hsa-miR-3143	CLIP-seq
MIRT768943	hsa-miR-3150b-3p	CLIP-seq
MIRT768944	hsa-miR-3180-5p	CLIP-seq
MIRT768945	hsa-miR-3182	CLIP-seq
MIRT768915	hsa-miR-3184	CLIP-seq
MIRT768946	hsa-miR-320a	CLIP-seq
MIRT768947	hsa-miR-320b	CLIP-seq
MIRT768948	hsa-miR-320c	CLIP-seq
MIRT768949	hsa-miR-320d	CLIP-seq
MIRT768916	hsa-miR-3649	CLIP-seq
MIRT768950	hsa-miR-3686	CLIP-seq
MIRT768917	hsa-miR-3690	CLIP-seq
MIRT768951	hsa-miR-376c	CLIP-seq
MIRT768920	hsa-miR-423-5p	CLIP-seq
MIRT768921	hsa-miR-4316	CLIP-seq
MIRT768922	hsa-miR-4426	CLIP-seq
MIRT768952	hsa-miR-4429	CLIP-seq
MIRT768953	hsa-miR-4443	CLIP-seq
MIRT768954	hsa-miR-4446-5p	CLIP-seq
MIRT768955	hsa-miR-4452	CLIP-seq
MIRT768956	hsa-miR-4477a	CLIP-seq
MIRT768957	hsa-miR-4480	CLIP-seq
MIRT768958	hsa-miR-455-3p	CLIP-seq
MIRT768923	hsa-miR-4635	CLIP-seq
MIRT768924	hsa-miR-4638-3p	CLIP-seq
MIRT768959	hsa-miR-4645-5p	CLIP-seq
MIRT768925	hsa-miR-4647	CLIP-seq
MIRT768960	hsa-miR-4659a-3p	CLIP-seq
MIRT768961	hsa-miR-4659b-3p	CLIP-seq
MIRT768926	hsa-miR-4662b	CLIP-seq
MIRT768962	hsa-miR-4673	CLIP-seq
MIRT768927	hsa-miR-4677-3p	CLIP-seq
MIRT768928	hsa-miR-4679	CLIP-seq
MIRT768963	hsa-miR-4684-5p	CLIP-seq
MIRT768964	hsa-miR-4698	CLIP-seq
MIRT768965	hsa-miR-4709-3p	CLIP-seq
MIRT768966	hsa-miR-4711-3p	CLIP-seq
MIRT768967	hsa-miR-4711-5p	CLIP-seq
MIRT768968	hsa-miR-4762-3p	CLIP-seq
MIRT768969	hsa-miR-4775	CLIP-seq
MIRT768970	hsa-miR-4777-5p	CLIP-seq
MIRT768971	hsa-miR-4784	CLIP-seq
MIRT768929	hsa-miR-4786-3p	CLIP-seq
MIRT768972	hsa-miR-518d-5p	CLIP-seq
MIRT768973	hsa-miR-519b-5p	CLIP-seq
MIRT768974	hsa-miR-519c-5p	CLIP-seq
MIRT768975	hsa-miR-520a-5p	CLIP-seq
MIRT768976	hsa-miR-520c-5p	CLIP-seq
MIRT768977	hsa-miR-522	CLIP-seq
MIRT768978	hsa-miR-525-5p	CLIP-seq
MIRT768979	hsa-miR-526a	CLIP-seq
MIRT768980	hsa-miR-590-3p	CLIP-seq
MIRT768937	hsa-miR-593	CLIP-seq
MIRT768939	hsa-miR-603	CLIP-seq
MIRT768981	hsa-miR-765	CLIP-seq
MIRT768908	hsa-miR-127-5p	CLIP-seq
MIRT1926738	hsa-miR-137	CLIP-seq
MIRT1926739	hsa-miR-1587	CLIP-seq
MIRT1926740	hsa-miR-2355-5p	CLIP-seq
MIRT768943	hsa-miR-3150b-3p	CLIP-seq
MIRT1926741	hsa-miR-3189-5p	CLIP-seq
MIRT1926742	hsa-miR-4312	CLIP-seq
MIRT1926743	hsa-miR-4417	CLIP-seq
MIRT1926744	hsa-miR-4453	CLIP-seq
MIRT1926745	hsa-miR-4455	CLIP-seq
MIRT1926746	hsa-miR-4492	CLIP-seq
MIRT1926747	hsa-miR-4498	CLIP-seq
MIRT1926748	hsa-miR-4538	CLIP-seq
MIRT1926749	hsa-miR-4656	CLIP-seq
MIRT768960	hsa-miR-4659a-3p	CLIP-seq
MIRT768961	hsa-miR-4659b-3p	CLIP-seq
MIRT1926750	hsa-miR-4663	CLIP-seq
MIRT1926751	hsa-miR-4675	CLIP-seq
MIRT1926752	hsa-miR-4689	CLIP-seq
MIRT1926753	hsa-miR-4741	CLIP-seq
MIRT1926754	hsa-miR-4758-3p	CLIP-seq
MIRT1926755	hsa-miR-4779	CLIP-seq
MIRT768971	hsa-miR-4784	CLIP-seq
MIRT1926756	hsa-miR-4796-3p	CLIP-seq
MIRT768932	hsa-miR-532-5p	CLIP-seq
MIRT1926757	hsa-miR-591	CLIP-seq
MIRT1926758	hsa-miR-609	CLIP-seq
MIRT1926759	hsa-miR-628-5p	CLIP-seq
MIRT1926760	hsa-miR-762	CLIP-seq
MIRT768909	hsa-miR-1278	CLIP-seq
MIRT768910	hsa-miR-1294	CLIP-seq
MIRT2167719	hsa-miR-3074-5p	CLIP-seq
MIRT768942	hsa-miR-3143	CLIP-seq
MIRT768943	hsa-miR-3150b-3p	CLIP-seq
MIRT768944	hsa-miR-3180-5p	CLIP-seq
MIRT768945	hsa-miR-3182	CLIP-seq
MIRT2167720	hsa-miR-3183	CLIP-seq
MIRT768915	hsa-miR-3184	CLIP-seq
MIRT768916	hsa-miR-3649	CLIP-seq
MIRT768950	hsa-miR-3686	CLIP-seq
MIRT2167721	hsa-miR-370	CLIP-seq
MIRT768951	hsa-miR-376c	CLIP-seq
MIRT768918	hsa-miR-3973	CLIP-seq
MIRT768919	hsa-miR-410	CLIP-seq
MIRT768920	hsa-miR-423-5p	CLIP-seq
MIRT768921	hsa-miR-4316	CLIP-seq
MIRT768922	hsa-miR-4426	CLIP-seq
MIRT768956	hsa-miR-4477a	CLIP-seq
MIRT768959	hsa-miR-4645-5p	CLIP-seq
MIRT768925	hsa-miR-4647	CLIP-seq
MIRT768960	hsa-miR-4659a-3p	CLIP-seq
MIRT768961	hsa-miR-4659b-3p	CLIP-seq
MIRT768926	hsa-miR-4662b	CLIP-seq
MIRT768962	hsa-miR-4673	CLIP-seq
MIRT768927	hsa-miR-4677-3p	CLIP-seq
MIRT768928	hsa-miR-4679	CLIP-seq
MIRT768967	hsa-miR-4711-5p	CLIP-seq
MIRT2167722	hsa-miR-4723-3p	CLIP-seq
MIRT768968	hsa-miR-4762-3p	CLIP-seq
MIRT768971	hsa-miR-4784	CLIP-seq
MIRT768975	hsa-miR-520a-5p	CLIP-seq
MIRT768930	hsa-miR-520g	CLIP-seq
MIRT768931	hsa-miR-520h	CLIP-seq
MIRT768978	hsa-miR-525-5p	CLIP-seq
MIRT768932	hsa-miR-532-5p	CLIP-seq
MIRT768933	hsa-miR-548k	CLIP-seq
MIRT768937	hsa-miR-593	CLIP-seq
MIRT1926740	hsa-miR-2355-5p	CLIP-seq
MIRT768943	hsa-miR-3150b-3p	CLIP-seq
MIRT1926741	hsa-miR-3189-5p	CLIP-seq
MIRT1926742	hsa-miR-4312	CLIP-seq
MIRT1926750	hsa-miR-4663	CLIP-seq
MIRT1926752	hsa-miR-4689	CLIP-seq
MIRT1926754	hsa-miR-4758-3p	CLIP-seq
MIRT1926755	hsa-miR-4779	CLIP-seq
MIRT768971	hsa-miR-4784	CLIP-seq
MIRT768932	hsa-miR-532-5p	CLIP-seq
MIRT1926757	hsa-miR-591	CLIP-seq
MIRT1926759	hsa-miR-628-5p	CLIP-seq
MIRT2470379	hsa-miR-1236	CLIP-seq
MIRT2470380	hsa-miR-1263	CLIP-seq
MIRT768908	hsa-miR-127-5p	CLIP-seq
MIRT768910	hsa-miR-1294	CLIP-seq
MIRT1926738	hsa-miR-137	CLIP-seq
MIRT1926739	hsa-miR-1587	CLIP-seq
MIRT1926740	hsa-miR-2355-5p	CLIP-seq
MIRT768943	hsa-miR-3150b-3p	CLIP-seq
MIRT2167720	hsa-miR-3183	CLIP-seq
MIRT768915	hsa-miR-3184	CLIP-seq
MIRT1926741	hsa-miR-3189-5p	CLIP-seq
MIRT2470381	hsa-miR-3688-3p	CLIP-seq
MIRT2470382	hsa-miR-3978	CLIP-seq
MIRT768920	hsa-miR-423-5p	CLIP-seq
MIRT2470383	hsa-miR-4291	CLIP-seq
MIRT1926742	hsa-miR-4312	CLIP-seq
MIRT768921	hsa-miR-4316	CLIP-seq
MIRT1926743	hsa-miR-4417	CLIP-seq
MIRT1926744	hsa-miR-4453	CLIP-seq
MIRT1926745	hsa-miR-4455	CLIP-seq
MIRT1926746	hsa-miR-4492	CLIP-seq
MIRT2470384	hsa-miR-4494	CLIP-seq
MIRT1926747	hsa-miR-4498	CLIP-seq
MIRT1926748	hsa-miR-4538	CLIP-seq
MIRT1926749	hsa-miR-4656	CLIP-seq
MIRT1926750	hsa-miR-4663	CLIP-seq
MIRT2470385	hsa-miR-4670-3p	CLIP-seq
MIRT1926751	hsa-miR-4675	CLIP-seq
MIRT768927	hsa-miR-4677-3p	CLIP-seq
MIRT768928	hsa-miR-4679	CLIP-seq
MIRT1926752	hsa-miR-4689	CLIP-seq
MIRT2470386	hsa-miR-4694-3p	CLIP-seq
MIRT2167722	hsa-miR-4723-3p	CLIP-seq
MIRT1926753	hsa-miR-4741	CLIP-seq
MIRT1926754	hsa-miR-4758-3p	CLIP-seq
MIRT1926755	hsa-miR-4779	CLIP-seq
MIRT768971	hsa-miR-4784	CLIP-seq
MIRT1926756	hsa-miR-4796-3p	CLIP-seq
MIRT2470387	hsa-miR-499a-5p	CLIP-seq
MIRT768932	hsa-miR-532-5p	CLIP-seq
MIRT2470388	hsa-miR-545	CLIP-seq
MIRT2470389	hsa-miR-561	CLIP-seq
MIRT1926757	hsa-miR-591	CLIP-seq
MIRT768937	hsa-miR-593	CLIP-seq
MIRT1926758	hsa-miR-609	CLIP-seq
MIRT1926759	hsa-miR-628-5p	CLIP-seq
MIRT1926760	hsa-miR-762	CLIP-seq
MIRT768910	hsa-miR-1294	CLIP-seq
MIRT1926738	hsa-miR-137	CLIP-seq
MIRT1926739	hsa-miR-1587	CLIP-seq
MIRT1926740	hsa-miR-2355-5p	CLIP-seq
MIRT768943	hsa-miR-3150b-3p	CLIP-seq
MIRT768915	hsa-miR-3184	CLIP-seq
MIRT1926741	hsa-miR-3189-5p	CLIP-seq
MIRT2470381	hsa-miR-3688-3p	CLIP-seq
MIRT2470382	hsa-miR-3978	CLIP-seq
MIRT768920	hsa-miR-423-5p	CLIP-seq
MIRT1926742	hsa-miR-4312	CLIP-seq
MIRT768921	hsa-miR-4316	CLIP-seq
MIRT1926743	hsa-miR-4417	CLIP-seq
MIRT1926745	hsa-miR-4455	CLIP-seq
MIRT1926746	hsa-miR-4492	CLIP-seq
MIRT1926747	hsa-miR-4498	CLIP-seq
MIRT1926749	hsa-miR-4656	CLIP-seq
MIRT1926750	hsa-miR-4663	CLIP-seq
MIRT1926751	hsa-miR-4675	CLIP-seq
MIRT768927	hsa-miR-4677-3p	CLIP-seq
MIRT768928	hsa-miR-4679	CLIP-seq
MIRT1926752	hsa-miR-4689	CLIP-seq
MIRT2470386	hsa-miR-4694-3p	CLIP-seq
MIRT1926753	hsa-miR-4741	CLIP-seq
MIRT1926754	hsa-miR-4758-3p	CLIP-seq
MIRT1926755	hsa-miR-4779	CLIP-seq
MIRT768971	hsa-miR-4784	CLIP-seq
MIRT1926756	hsa-miR-4796-3p	CLIP-seq
MIRT768932	hsa-miR-532-5p	CLIP-seq
MIRT2470389	hsa-miR-561	CLIP-seq
MIRT1926757	hsa-miR-591	CLIP-seq
MIRT768937	hsa-miR-593	CLIP-seq
MIRT1926758	hsa-miR-609	CLIP-seq
MIRT1926759	hsa-miR-628-5p	CLIP-seq
MIRT1926760	hsa-miR-762	CLIP-seq

Transcription factors

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Transcription factor	Regulation	Reference
ATF3	Repression	20696134
FOXO1	Activation	20125105

Show/Hide all(39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	29190778, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	12802337, 19233263
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0009755	Process	Hormone-mediated signaling pathway	IDA	12802337
GO:0010633	Process	Negative regulation of epithelial cell migration	IMP	23776679
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IMP	23776679
GO:0010906	Process	Regulation of glucose metabolic process	IEA
GO:0010906	Process	Regulation of glucose metabolic process	ISS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0019216	Process	Regulation of lipid metabolic process	IEA
GO:0019216	Process	Regulation of lipid metabolic process	ISS
GO:0019395	Process	Fatty acid oxidation	IDA	12802337
GO:0019901	Function	Protein kinase binding	IPI	19233263
GO:0030308	Process	Negative regulation of cell growth	IEA
GO:0033210	Process	Leptin-mediated signaling pathway	IEA
GO:0033211	Process	Adiponectin-activated signaling pathway	IBA
GO:0033211	Process	Adiponectin-activated signaling pathway	IDA	12802337
GO:0033211	Process	Adiponectin-activated signaling pathway	IEA
GO:0033211	Process	Adiponectin-activated signaling pathway	IEA
GO:0038023	Function	Signaling receptor activity	IBA
GO:0038023	Function	Signaling receptor activity	IEA
GO:0042593	Process	Glucose homeostasis	IEA
GO:0042593	Process	Glucose homeostasis	ISS
GO:0042802	Function	Identical protein binding	IEA
GO:0046426	Process	Negative regulation of receptor signaling pathway via JAK-STAT	IMP	23776679
GO:0046427	Process	Positive regulation of receptor signaling pathway via JAK-STAT	IEA
GO:0046628	Process	Positive regulation of insulin receptor signaling pathway	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0055100	Function	Adiponectin binding	IDA	12802337
GO:0055100	Function	Adiponectin binding	IEA
GO:0097003	Function	Adipokinetic hormone receptor activity	IDA	12802337
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	IEA
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	ISS	24531262
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	IMP	23776679

MIM	HGNC	e!Ensembl
607945	24040	ENSG00000159346

Protein

UniProt ID

Q96A54

Protein name

Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member 1) (Progestin and adipoQ receptor family member I)

Protein function

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-bin

PDB

5LXG , 6KRZ , 6KS0

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03006	HlyIII	129 → 352	Haemolysin-III related	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed (PubMed:16044242). Highly expressed in heart and skeletal muscle (PubMed:12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337). Wea

Sequence

MSSHKGSVVAQGNGAPASNREADTVELAELGPLLEEKGKRVIANPPKAEEEQTCPVPQEE
EEEVRVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPS
FRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGA
VLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLS
IVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQM
GWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQE
FRYGLEGGCTDDTLL

Sequence length

375

Interactions

View interactions

	KEGG		Reactome
	Hormone signaling AMPK signaling pathway Longevity regulating pathway Adipocytokine signaling pathway Non-alcoholic fatty liver disease Alcoholic liver disease		AMPK inhibits chREBP transcriptional activation activity

ADIPOR1 (adiponectin receptor 1)