Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51088
Gene name Gene Name - the full gene name approved by the HGNC.
Kelch like family member 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
KLHL5
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4p14
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018473 hsa-miR-335-5p Microarray 18185580
MIRT020925 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT724517 hsa-miR-4517 HITS-CLIP 19536157
MIRT724516 hsa-miR-5583-3p HITS-CLIP 19536157
MIRT724515 hsa-miR-3127-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0003779 Function Actin binding IEA
GO:0005515 Function Protein binding IPI 21145461, 21988832
GO:0005737 Component Cytoplasm NAS 14672410
GO:0005829 Component Cytosol TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608064 6356 ENSG00000109790
Protein
UniProt ID Q96PQ7
Protein name Kelch-like protein 5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00651 BTB 210 317 BTB/POZ domain Domain
PF07707 BACK 322 423 BTB And C-terminal Kelch Domain
PF01344 Kelch_1 467 501 Kelch motif Repeat
PF01344 Kelch_1 503 548 Kelch motif Repeat
PF01344 Kelch_1 550 595 Kelch motif Repeat
PF01344 Kelch_1 597 642 Kelch motif Repeat
PF01344 Kelch_1 644 695 Kelch motif Repeat
PF01344 Kelch_1 697 741 Kelch motif Repeat
Tissue specificity TISSUE SPECIFICITY: Expressed in adrenal gland, ovary and thyroid gland and less abundantly in lymph node, prostate, spinal cord, testis and trachea.
Sequence
Sequence length 755
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Asthma Childhood asthma, Asthma 23829686 ClinVar, GWAS
Glaucoma Glaucoma GWAS
Associations from Text Mining
Disease Name Relationship Type References
Hemangioma capillary infantile Associate 36181115
Liver Diseases Associate 37981173