Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51072
Gene name Gene Name - the full gene name approved by the HGNC.	Mediator of cell motility 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MEMO1
Synonyms (NCBI Gene) Gene synonyms aliases	C2orf4, CGI-27, MEMO, NS5ATP7
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2p22.3

Show/Hide all(191)

miRTarBase ID	miRNA	Experiments	Reference
MIRT648563	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT648562	hsa-miR-4477a	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615881	hsa-miR-3609	HITS-CLIP	23824327
MIRT615880	hsa-miR-548ah-5p	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT473356	hsa-miR-324-5p	PAR-CLIP	23592263
MIRT473353	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT473350	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT473349	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT473348	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT473347	hsa-miR-3687	PAR-CLIP	23592263
MIRT473346	hsa-miR-4442	PAR-CLIP	23592263
MIRT473344	hsa-miR-3665	PAR-CLIP	23592263
MIRT473343	hsa-miR-657	PAR-CLIP	23592263
MIRT473339	hsa-miR-3944-5p	PAR-CLIP	23592263
MIRT473338	hsa-miR-143-5p	PAR-CLIP	23592263
MIRT473337	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT473335	hsa-miR-4642	PAR-CLIP	23592263
MIRT473356	hsa-miR-324-5p	PAR-CLIP	23592263
MIRT473353	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT473354	hsa-miR-3929	PAR-CLIP	23592263
MIRT473352	hsa-miR-4419b	PAR-CLIP	23592263
MIRT473351	hsa-miR-4478	PAR-CLIP	23592263
MIRT473350	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT473349	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT473348	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT473347	hsa-miR-3687	PAR-CLIP	23592263
MIRT473346	hsa-miR-4442	PAR-CLIP	23592263
MIRT473345	hsa-miR-645	PAR-CLIP	23592263
MIRT473344	hsa-miR-3665	PAR-CLIP	23592263
MIRT473343	hsa-miR-657	PAR-CLIP	23592263
MIRT473342	hsa-miR-4505	PAR-CLIP	23592263
MIRT473341	hsa-miR-5787	PAR-CLIP	23592263
MIRT473340	hsa-miR-3649	PAR-CLIP	23592263
MIRT473339	hsa-miR-3944-5p	PAR-CLIP	23592263
MIRT473338	hsa-miR-143-5p	PAR-CLIP	23592263
MIRT473337	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT473335	hsa-miR-4642	PAR-CLIP	23592263
MIRT648563	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT648562	hsa-miR-4477a	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT615881	hsa-miR-3609	HITS-CLIP	23824327
MIRT615880	hsa-miR-548ah-5p	HITS-CLIP	23824327
MIRT615879	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT473356	hsa-miR-324-5p	PAR-CLIP	23592263
MIRT473353	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT473350	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT473349	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT473348	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT473347	hsa-miR-3687	PAR-CLIP	23592263
MIRT473346	hsa-miR-4442	PAR-CLIP	23592263
MIRT473344	hsa-miR-3665	PAR-CLIP	23592263
MIRT473343	hsa-miR-657	PAR-CLIP	23592263
MIRT473339	hsa-miR-3944-5p	PAR-CLIP	23592263
MIRT473338	hsa-miR-143-5p	PAR-CLIP	23592263
MIRT473337	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT473335	hsa-miR-4642	PAR-CLIP	23592263
MIRT473356	hsa-miR-324-5p	PAR-CLIP	23592263
MIRT473353	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT473354	hsa-miR-3929	PAR-CLIP	23592263
MIRT473352	hsa-miR-4419b	PAR-CLIP	23592263
MIRT473351	hsa-miR-4478	PAR-CLIP	23592263
MIRT473350	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT473349	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT473348	hsa-miR-4712-3p	PAR-CLIP	23592263
MIRT473347	hsa-miR-3687	PAR-CLIP	23592263
MIRT473346	hsa-miR-4442	PAR-CLIP	23592263
MIRT473345	hsa-miR-645	PAR-CLIP	23592263
MIRT473344	hsa-miR-3665	PAR-CLIP	23592263
MIRT473343	hsa-miR-657	PAR-CLIP	23592263
MIRT473342	hsa-miR-4505	PAR-CLIP	23592263
MIRT473341	hsa-miR-5787	PAR-CLIP	23592263
MIRT473340	hsa-miR-3649	PAR-CLIP	23592263
MIRT473339	hsa-miR-3944-5p	PAR-CLIP	23592263
MIRT473338	hsa-miR-143-5p	PAR-CLIP	23592263
MIRT473337	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT473335	hsa-miR-4642	PAR-CLIP	23592263
MIRT1142871	hsa-miR-130a	CLIP-seq
MIRT1142872	hsa-miR-130b	CLIP-seq
MIRT1142873	hsa-miR-19a	CLIP-seq
MIRT1142874	hsa-miR-19b	CLIP-seq
MIRT1142875	hsa-miR-2276	CLIP-seq
MIRT1142876	hsa-miR-301a	CLIP-seq
MIRT1142877	hsa-miR-301b	CLIP-seq
MIRT1142878	hsa-miR-3201	CLIP-seq
MIRT1142879	hsa-miR-3666	CLIP-seq
MIRT1142880	hsa-miR-3669	CLIP-seq
MIRT1142881	hsa-miR-4295	CLIP-seq
MIRT1142882	hsa-miR-454	CLIP-seq
MIRT1142883	hsa-miR-455-5p	CLIP-seq
MIRT1142884	hsa-miR-4766-5p	CLIP-seq
MIRT1142885	hsa-miR-4772-3p	CLIP-seq
MIRT1142886	hsa-miR-4778-5p	CLIP-seq
MIRT1142887	hsa-miR-4791	CLIP-seq
MIRT1142888	hsa-miR-518a-5p	CLIP-seq
MIRT1142889	hsa-miR-527	CLIP-seq
MIRT1142890	hsa-miR-651	CLIP-seq
MIRT1142891	hsa-miR-1267	CLIP-seq
MIRT1142892	hsa-miR-129-3p	CLIP-seq
MIRT1142871	hsa-miR-130a	CLIP-seq
MIRT1142872	hsa-miR-130b	CLIP-seq
MIRT1142893	hsa-miR-1323	CLIP-seq
MIRT1142873	hsa-miR-19a	CLIP-seq
MIRT1142874	hsa-miR-19b	CLIP-seq
MIRT1142875	hsa-miR-2276	CLIP-seq
MIRT1142876	hsa-miR-301a	CLIP-seq
MIRT1142877	hsa-miR-301b	CLIP-seq
MIRT1142894	hsa-miR-3121-3p	CLIP-seq
MIRT1142895	hsa-miR-3154	CLIP-seq
MIRT1142896	hsa-miR-3613-3p	CLIP-seq
MIRT1142897	hsa-miR-3613-5p	CLIP-seq
MIRT1142879	hsa-miR-3666	CLIP-seq
MIRT1142880	hsa-miR-3669	CLIP-seq
MIRT1142881	hsa-miR-4295	CLIP-seq
MIRT1142898	hsa-miR-450b-5p	CLIP-seq
MIRT1142882	hsa-miR-454	CLIP-seq
MIRT1142883	hsa-miR-455-5p	CLIP-seq
MIRT1142899	hsa-miR-4687-5p	CLIP-seq
MIRT1142900	hsa-miR-4766-3p	CLIP-seq
MIRT1142884	hsa-miR-4766-5p	CLIP-seq
MIRT1142885	hsa-miR-4772-3p	CLIP-seq
MIRT1142886	hsa-miR-4778-5p	CLIP-seq
MIRT1142888	hsa-miR-518a-5p	CLIP-seq
MIRT1142889	hsa-miR-527	CLIP-seq
MIRT1142901	hsa-miR-548a-3p	CLIP-seq
MIRT1142902	hsa-miR-548ae	CLIP-seq
MIRT1142903	hsa-miR-548aj	CLIP-seq
MIRT1142904	hsa-miR-548am	CLIP-seq
MIRT1142905	hsa-miR-548e	CLIP-seq
MIRT1142906	hsa-miR-548f	CLIP-seq
MIRT1142907	hsa-miR-548g	CLIP-seq
MIRT1142908	hsa-miR-548o	CLIP-seq
MIRT1142909	hsa-miR-548x	CLIP-seq
MIRT1142910	hsa-miR-607	CLIP-seq
MIRT2040674	hsa-miR-3667-3p	CLIP-seq
MIRT1142880	hsa-miR-3669	CLIP-seq
MIRT1142883	hsa-miR-455-5p	CLIP-seq
MIRT1142884	hsa-miR-4766-5p	CLIP-seq
MIRT1142891	hsa-miR-1267	CLIP-seq
MIRT2270387	hsa-miR-203	CLIP-seq
MIRT2270388	hsa-miR-219-1-3p	CLIP-seq
MIRT1142894	hsa-miR-3121-3p	CLIP-seq
MIRT2270389	hsa-miR-3132	CLIP-seq
MIRT1142895	hsa-miR-3154	CLIP-seq
MIRT1142897	hsa-miR-3613-5p	CLIP-seq
MIRT1142900	hsa-miR-4766-3p	CLIP-seq
MIRT2270390	hsa-miR-571	CLIP-seq
MIRT2270391	hsa-miR-582-3p	CLIP-seq
MIRT2040674	hsa-miR-3667-3p	CLIP-seq
MIRT2569579	hsa-miR-1202	CLIP-seq
MIRT2569580	hsa-miR-142-5p	CLIP-seq
MIRT2270387	hsa-miR-203	CLIP-seq
MIRT2270388	hsa-miR-219-1-3p	CLIP-seq
MIRT2569581	hsa-miR-3064-3p	CLIP-seq
MIRT2569582	hsa-miR-3157-3p	CLIP-seq
MIRT2569583	hsa-miR-3194-5p	CLIP-seq
MIRT2569584	hsa-miR-340	CLIP-seq
MIRT2569585	hsa-miR-3614-3p	CLIP-seq
MIRT2040674	hsa-miR-3667-3p	CLIP-seq
MIRT2569586	hsa-miR-3972	CLIP-seq
MIRT2569587	hsa-miR-4297	CLIP-seq
MIRT2569588	hsa-miR-4422	CLIP-seq
MIRT2569589	hsa-miR-4436b-5p	CLIP-seq
MIRT2569590	hsa-miR-4698	CLIP-seq
MIRT2270390	hsa-miR-571	CLIP-seq
MIRT2569579	hsa-miR-1202	CLIP-seq
MIRT2569580	hsa-miR-142-5p	CLIP-seq
MIRT2270387	hsa-miR-203	CLIP-seq
MIRT2270388	hsa-miR-219-1-3p	CLIP-seq
MIRT2569581	hsa-miR-3064-3p	CLIP-seq
MIRT2569582	hsa-miR-3157-3p	CLIP-seq
MIRT2569583	hsa-miR-3194-5p	CLIP-seq
MIRT2569584	hsa-miR-340	CLIP-seq
MIRT2569585	hsa-miR-3614-3p	CLIP-seq
MIRT2040674	hsa-miR-3667-3p	CLIP-seq
MIRT2569586	hsa-miR-3972	CLIP-seq
MIRT2569587	hsa-miR-4297	CLIP-seq
MIRT2569588	hsa-miR-4422	CLIP-seq
MIRT2569589	hsa-miR-4436b-5p	CLIP-seq
MIRT2684835	hsa-miR-4476	CLIP-seq
MIRT2684836	hsa-miR-4477b	CLIP-seq
MIRT2684837	hsa-miR-4533	CLIP-seq
MIRT2569590	hsa-miR-4698	CLIP-seq
MIRT2684838	hsa-miR-4759	CLIP-seq
MIRT2270390	hsa-miR-571	CLIP-seq
MIRT2040674	hsa-miR-3667-3p	CLIP-seq

Show/Hide all(5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21516116, 21840311, 25416956, 32296183, 33961781
GO:0005634	Component	Nucleus	HDA	16780588
GO:0005829	Component	Cytosol	HDA	16780588
GO:0005829	Component	Cytosol	TAS
GO:0032886	Process	Regulation of microtubule-based process	IMP	20937854

MIM	HGNC	e!Ensembl
611786	14014	ENSG00000162959

Protein

UniProt ID

Q9Y316

Protein name

Protein MEMO1 (C21orf19-like protein) (Hepatitis C virus NS5A-transactivated protein 7) (HCV NS5A-transactivated protein 7) (Mediator of ErbB2-driven cell motility 1) (Mediator of cell motility 1) (Memo-1)

Protein function

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubul

PDB

3BCZ , 3BD0 , 7KQ8 , 7L5C , 7M8H

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01875	Memo	9 → 293	Memo-like protein	Family

Sequence

MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYCGSCAA
HAYKQVDPSITRRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFE
RMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADP
SNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYH
NTICGRHPIGVLLNAITELQKNGMNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH

Sequence length

297

Interactions

View interactions

	Reactome
			ERBB2 Regulates Cell Motility

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Glioblastoma	Glioblastoma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	37487298, 38640016
Carcinoma Intraductal Noninfiltrating	Associate	21375733
Colorectal Neoplasms	Associate	33218285
COVID 19	Associate	37990144
Neoplasm Metastasis	Associate	35581960
Neoplasms	Inhibit	21375733
Neoplasms	Associate	36197110, 37487298, 38640016
Stomach Neoplasms	Associate	35581960
Uterine Cervical Neoplasms	Associate	36197110

MEMO1 (mediator of cell motility 1)