ST8SIA3 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3)

Gene

• Entrez ID: 51046
• Gene name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
• Gene symbol: ST8SIA3
• Synonyms (NCBI Gene): SIAT8C, ST8SiaIII
• Chromosome: 18
• Chromosome location: 18q21.31
• Summary: ST8SIA3 belongs to a family of sialyltransferases that form sialyl-alpha-2,8-sialyl-R linkages at the nonreducing termini of glycoconjugates (Lee et al., 1998 [PubMed 9826427]).[supplied by OMIM, Mar 2008]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT723465	hsa-miR-4425	HITS-CLIP	19536157
MIRT723464	hsa-miR-3147	HITS-CLIP	19536157
MIRT723463	hsa-miR-5701	HITS-CLIP	19536157
MIRT723462	hsa-miR-4273	HITS-CLIP	19536157
MIRT723461	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT723460	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT723459	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT641152	hsa-miR-5584-5p	HITS-CLIP	23824327
MIRT653076	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT653075	hsa-miR-4257	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT641151	hsa-miR-4469	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627508	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT641152	hsa-miR-5584-5p	HITS-CLIP	23824327
MIRT653076	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT653075	hsa-miR-4257	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT627511	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT627510	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT641152	hsa-miR-5584-5p	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT627511	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT641151	hsa-miR-4469	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627508	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT627511	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT627510	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627508	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT723465	hsa-miR-4425	HITS-CLIP	19536157
MIRT723464	hsa-miR-3147	HITS-CLIP	19536157
MIRT723463	hsa-miR-5701	HITS-CLIP	19536157
MIRT723462	hsa-miR-4273	HITS-CLIP	19536157
MIRT723461	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT723460	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT723459	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT641152	hsa-miR-5584-5p	HITS-CLIP	23824327
MIRT653076	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT653075	hsa-miR-4257	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT641151	hsa-miR-4469	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627508	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT641152	hsa-miR-5584-5p	HITS-CLIP	23824327
MIRT653076	hsa-miR-6847-5p	HITS-CLIP	23824327
MIRT653075	hsa-miR-4257	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT627511	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT627510	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT641152	hsa-miR-5584-5p	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT627511	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT641151	hsa-miR-4469	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627508	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT627513	hsa-miR-6873-5p	HITS-CLIP	23824327
MIRT627512	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT627511	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT627510	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT627509	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT627508	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT627507	hsa-miR-507	HITS-CLIP	23824327
MIRT627506	hsa-miR-557	HITS-CLIP	23824327
MIRT627505	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT627504	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT1394002	hsa-miR-1178	CLIP-seq
MIRT1394003	hsa-miR-1179	CLIP-seq
MIRT1394004	hsa-miR-1185	CLIP-seq
MIRT1394005	hsa-miR-1193	CLIP-seq
MIRT1394006	hsa-miR-1208	CLIP-seq
MIRT1394007	hsa-miR-1238	CLIP-seq
MIRT1394008	hsa-miR-1265	CLIP-seq
MIRT1394009	hsa-miR-1266	CLIP-seq
MIRT1394010	hsa-miR-1276	CLIP-seq
MIRT1394011	hsa-miR-128	CLIP-seq
MIRT1394012	hsa-miR-1294	CLIP-seq
MIRT1394013	hsa-miR-1299	CLIP-seq
MIRT1394014	hsa-miR-137	CLIP-seq
MIRT1394015	hsa-miR-142-5p	CLIP-seq
MIRT1394016	hsa-miR-144	CLIP-seq
MIRT1394017	hsa-miR-145	CLIP-seq
MIRT1394018	hsa-miR-1825	CLIP-seq
MIRT1394019	hsa-miR-192	CLIP-seq
MIRT1394020	hsa-miR-199a-5p	CLIP-seq
MIRT1394021	hsa-miR-199b-5p	CLIP-seq
MIRT1394022	hsa-miR-2052	CLIP-seq
MIRT1394023	hsa-miR-2053	CLIP-seq
MIRT1394024	hsa-miR-215	CLIP-seq
MIRT1394025	hsa-miR-217	CLIP-seq
MIRT1394026	hsa-miR-218	CLIP-seq
MIRT1394027	hsa-miR-2392	CLIP-seq
MIRT1394028	hsa-miR-2682	CLIP-seq
MIRT1394029	hsa-miR-302f	CLIP-seq
MIRT1394030	hsa-miR-3115	CLIP-seq
MIRT1394031	hsa-miR-3117-5p	CLIP-seq
MIRT1394032	hsa-miR-3121-3p	CLIP-seq
MIRT1394033	hsa-miR-3130-3p	CLIP-seq
MIRT1394034	hsa-miR-3140-3p	CLIP-seq
MIRT1394035	hsa-miR-3140-5p	CLIP-seq
MIRT1394036	hsa-miR-3143	CLIP-seq
MIRT1394037	hsa-miR-3153	CLIP-seq
MIRT1394038	hsa-miR-3179	CLIP-seq
MIRT1394039	hsa-miR-3180-5p	CLIP-seq
MIRT1394040	hsa-miR-323-5p	CLIP-seq
MIRT1394041	hsa-miR-340	CLIP-seq
MIRT1394042	hsa-miR-34a	CLIP-seq
MIRT1394043	hsa-miR-34c-5p	CLIP-seq
MIRT1394044	hsa-miR-3605-5p	CLIP-seq
MIRT1394045	hsa-miR-3609	CLIP-seq
MIRT1394046	hsa-miR-3657	CLIP-seq
MIRT1394047	hsa-miR-3660	CLIP-seq
MIRT1394048	hsa-miR-3663-5p	CLIP-seq
MIRT1394049	hsa-miR-3664-3p	CLIP-seq
MIRT1394050	hsa-miR-3676	CLIP-seq
MIRT1394051	hsa-miR-3679-5p	CLIP-seq
MIRT1394052	hsa-miR-3680	CLIP-seq
MIRT1394053	hsa-miR-383	CLIP-seq
MIRT1394054	hsa-miR-3920	CLIP-seq
MIRT1394055	hsa-miR-425	CLIP-seq
MIRT1394056	hsa-miR-4269	CLIP-seq
MIRT1394057	hsa-miR-4270	CLIP-seq
MIRT1394058	hsa-miR-4302	CLIP-seq
MIRT1394059	hsa-miR-4311	CLIP-seq
MIRT1394060	hsa-miR-4316	CLIP-seq
MIRT1394061	hsa-miR-4328	CLIP-seq
MIRT1394062	hsa-miR-4423-3p	CLIP-seq
MIRT1394063	hsa-miR-4434	CLIP-seq
MIRT1394064	hsa-miR-4441	CLIP-seq
MIRT1394065	hsa-miR-4476	CLIP-seq
MIRT1394066	hsa-miR-449a	CLIP-seq
MIRT1394067	hsa-miR-449b	CLIP-seq
MIRT1394068	hsa-miR-449c	CLIP-seq
MIRT1394069	hsa-miR-4514	CLIP-seq
MIRT1394070	hsa-miR-4516	CLIP-seq
MIRT1394071	hsa-miR-4517	CLIP-seq
MIRT1394072	hsa-miR-4518	CLIP-seq
MIRT1394073	hsa-miR-4526	CLIP-seq
MIRT1394074	hsa-miR-4659a-3p	CLIP-seq
MIRT1394075	hsa-miR-4659a-5p	CLIP-seq
MIRT1394076	hsa-miR-4659b-3p	CLIP-seq
MIRT1394077	hsa-miR-4659b-5p	CLIP-seq
MIRT1394078	hsa-miR-4669	CLIP-seq
MIRT1394079	hsa-miR-4680-3p	CLIP-seq
MIRT1394080	hsa-miR-4692	CLIP-seq
MIRT1394081	hsa-miR-4711-3p	CLIP-seq
MIRT1394082	hsa-miR-4711-5p	CLIP-seq
MIRT1394083	hsa-miR-4742-5p	CLIP-seq
MIRT1394084	hsa-miR-4753-5p	CLIP-seq
MIRT1394085	hsa-miR-4772-5p	CLIP-seq
MIRT1394086	hsa-miR-4776-3p	CLIP-seq
MIRT1394087	hsa-miR-4793-3p	CLIP-seq
MIRT1394088	hsa-miR-4796-5p	CLIP-seq
MIRT1394089	hsa-miR-522	CLIP-seq
MIRT1394090	hsa-miR-544	CLIP-seq
MIRT1394091	hsa-miR-548ah	CLIP-seq
MIRT1394092	hsa-miR-548c-3p	CLIP-seq
MIRT1394093	hsa-miR-548t	CLIP-seq
MIRT1394094	hsa-miR-570	CLIP-seq
MIRT1394095	hsa-miR-579	CLIP-seq
MIRT1394096	hsa-miR-583	CLIP-seq
MIRT1394097	hsa-miR-589	CLIP-seq
MIRT1394098	hsa-miR-616	CLIP-seq
MIRT1394099	hsa-miR-622	CLIP-seq
MIRT1394100	hsa-miR-636	CLIP-seq
MIRT1394101	hsa-miR-676	CLIP-seq
MIRT1394102	hsa-miR-873	CLIP-seq
MIRT1394103	hsa-miR-875-3p	CLIP-seq
MIRT1394104	hsa-miR-876-3p	CLIP-seq
MIRT1394105	hsa-miR-892a	CLIP-seq
MIRT1394106	hsa-miR-935	CLIP-seq
MIRT2118276	hsa-miR-106a	CLIP-seq
MIRT2118277	hsa-miR-106b	CLIP-seq
MIRT2118278	hsa-miR-1224-5p	CLIP-seq
MIRT2118279	hsa-miR-1271	CLIP-seq
MIRT2118280	hsa-miR-1288	CLIP-seq
MIRT2118281	hsa-miR-136	CLIP-seq
MIRT2118282	hsa-miR-143	CLIP-seq
MIRT2118283	hsa-miR-1587	CLIP-seq
MIRT2118284	hsa-miR-17	CLIP-seq
MIRT2118285	hsa-miR-181a	CLIP-seq
MIRT2118286	hsa-miR-181b	CLIP-seq
MIRT2118287	hsa-miR-181c	CLIP-seq
MIRT2118288	hsa-miR-181d	CLIP-seq
MIRT2118289	hsa-miR-1827	CLIP-seq
MIRT2118290	hsa-miR-20a	CLIP-seq
MIRT2118291	hsa-miR-20b	CLIP-seq
MIRT1394025	hsa-miR-217	CLIP-seq
MIRT2118292	hsa-miR-23a	CLIP-seq
MIRT2118293	hsa-miR-23b	CLIP-seq
MIRT2118294	hsa-miR-23c	CLIP-seq
MIRT1394028	hsa-miR-2682	CLIP-seq
MIRT2118295	hsa-miR-3120-5p	CLIP-seq
MIRT1394035	hsa-miR-3140-5p	CLIP-seq
MIRT2118296	hsa-miR-3169	CLIP-seq
MIRT2118297	hsa-miR-3185	CLIP-seq
MIRT2118298	hsa-miR-377	CLIP-seq
MIRT2118299	hsa-miR-3922-5p	CLIP-seq
MIRT2118300	hsa-miR-4251	CLIP-seq
MIRT2118301	hsa-miR-4262	CLIP-seq
MIRT1394056	hsa-miR-4269	CLIP-seq
MIRT2118302	hsa-miR-4293	CLIP-seq
MIRT2118303	hsa-miR-4299	CLIP-seq
MIRT2118304	hsa-miR-4329	CLIP-seq
MIRT2118305	hsa-miR-4427	CLIP-seq
MIRT1394068	hsa-miR-449c	CLIP-seq
MIRT2118306	hsa-miR-4539	CLIP-seq
MIRT2118307	hsa-miR-4656	CLIP-seq
MIRT1394079	hsa-miR-4680-3p	CLIP-seq
MIRT2118308	hsa-miR-4710	CLIP-seq
MIRT1394082	hsa-miR-4711-5p	CLIP-seq
MIRT2118309	hsa-miR-4751	CLIP-seq
MIRT2118310	hsa-miR-4753-3p	CLIP-seq
MIRT2118311	hsa-miR-4768-5p	CLIP-seq
MIRT2118312	hsa-miR-4770	CLIP-seq
MIRT2118313	hsa-miR-4775	CLIP-seq
MIRT2118314	hsa-miR-4792	CLIP-seq
MIRT2118315	hsa-miR-509-3p	CLIP-seq
MIRT2118316	hsa-miR-513b	CLIP-seq
MIRT2118317	hsa-miR-519d	CLIP-seq
MIRT2118318	hsa-miR-548a-3p	CLIP-seq
MIRT2118319	hsa-miR-548e	CLIP-seq
MIRT2118320	hsa-miR-548f	CLIP-seq
MIRT2118321	hsa-miR-548g	CLIP-seq
MIRT1394095	hsa-miR-579	CLIP-seq
MIRT2118322	hsa-miR-580	CLIP-seq
MIRT2118323	hsa-miR-596	CLIP-seq
MIRT2118324	hsa-miR-93	CLIP-seq
MIRT1394106	hsa-miR-935	CLIP-seq
MIRT2118325	hsa-miR-96	CLIP-seq
MIRT2118278	hsa-miR-1224-5p	CLIP-seq
MIRT2340317	hsa-miR-1231	CLIP-seq
MIRT1394009	hsa-miR-1266	CLIP-seq
MIRT2118280	hsa-miR-1288	CLIP-seq
MIRT2340318	hsa-miR-135a	CLIP-seq
MIRT2340319	hsa-miR-135b	CLIP-seq
MIRT2340320	hsa-miR-138	CLIP-seq
MIRT2118283	hsa-miR-1587	CLIP-seq
MIRT2340321	hsa-miR-18a	CLIP-seq
MIRT2340322	hsa-miR-18b	CLIP-seq
MIRT2340323	hsa-miR-205	CLIP-seq
MIRT1394025	hsa-miR-217	CLIP-seq
MIRT2340324	hsa-miR-2355-5p	CLIP-seq
MIRT2340325	hsa-miR-3065-3p	CLIP-seq
MIRT1394030	hsa-miR-3115	CLIP-seq
MIRT2118295	hsa-miR-3120-5p	CLIP-seq
MIRT2340326	hsa-miR-3163	CLIP-seq
MIRT2118296	hsa-miR-3169	CLIP-seq
MIRT1394045	hsa-miR-3609	CLIP-seq
MIRT1394049	hsa-miR-3664-3p	CLIP-seq
MIRT2340327	hsa-miR-3667-5p	CLIP-seq
MIRT2118298	hsa-miR-377	CLIP-seq
MIRT1394053	hsa-miR-383	CLIP-seq
MIRT2340328	hsa-miR-412	CLIP-seq
MIRT2118300	hsa-miR-4251	CLIP-seq
MIRT2340329	hsa-miR-4288	CLIP-seq
MIRT2340330	hsa-miR-4290	CLIP-seq
MIRT2118303	hsa-miR-4299	CLIP-seq
MIRT2118304	hsa-miR-4329	CLIP-seq
MIRT2340331	hsa-miR-4490	CLIP-seq
MIRT1394072	hsa-miR-4518	CLIP-seq
MIRT2118307	hsa-miR-4656	CLIP-seq
MIRT2340332	hsa-miR-4672	CLIP-seq
MIRT2340333	hsa-miR-4704-3p	CLIP-seq
MIRT2118308	hsa-miR-4710	CLIP-seq
MIRT1394081	hsa-miR-4711-3p	CLIP-seq
MIRT1394082	hsa-miR-4711-5p	CLIP-seq
MIRT2340334	hsa-miR-4720-5p	CLIP-seq
MIRT2340335	hsa-miR-4733-5p	CLIP-seq
MIRT2340336	hsa-miR-4735-3p	CLIP-seq
MIRT2118309	hsa-miR-4751	CLIP-seq
MIRT1394085	hsa-miR-4772-5p	CLIP-seq
MIRT2340337	hsa-miR-4777-5p	CLIP-seq
MIRT2118314	hsa-miR-4792	CLIP-seq
MIRT1394088	hsa-miR-4796-5p	CLIP-seq
MIRT2340338	hsa-miR-4799-3p	CLIP-seq
MIRT2118318	hsa-miR-548a-3p	CLIP-seq
MIRT1394091	hsa-miR-548ah	CLIP-seq
MIRT1394092	hsa-miR-548c-3p	CLIP-seq
MIRT2118319	hsa-miR-548e	CLIP-seq
MIRT2118320	hsa-miR-548f	CLIP-seq
MIRT2118321	hsa-miR-548g	CLIP-seq
MIRT2118322	hsa-miR-580	CLIP-seq
MIRT1394096	hsa-miR-583	CLIP-seq
MIRT2340339	hsa-miR-632	CLIP-seq
MIRT2340340	hsa-miR-642a	CLIP-seq
MIRT1394106	hsa-miR-935	CLIP-seq
MIRT2118278	hsa-miR-1224-5p	CLIP-seq
MIRT2395273	hsa-miR-1237	CLIP-seq
MIRT2395274	hsa-miR-1248	CLIP-seq
MIRT2395275	hsa-miR-1284	CLIP-seq
MIRT2118280	hsa-miR-1288	CLIP-seq
MIRT1394025	hsa-miR-217	CLIP-seq
MIRT2118296	hsa-miR-3169	CLIP-seq
MIRT2118303	hsa-miR-4299	CLIP-seq
MIRT2395276	hsa-miR-4704-5p	CLIP-seq
MIRT2118308	hsa-miR-4710	CLIP-seq
MIRT1394082	hsa-miR-4711-5p	CLIP-seq
MIRT2118309	hsa-miR-4751	CLIP-seq
MIRT2118314	hsa-miR-4792	CLIP-seq
MIRT1394002	hsa-miR-1178	CLIP-seq
MIRT1394029	hsa-miR-302f	CLIP-seq
MIRT2440833	hsa-miR-3647-3p	CLIP-seq
MIRT1394061	hsa-miR-4328	CLIP-seq
MIRT1394098	hsa-miR-616	CLIP-seq
MIRT2340337	hsa-miR-4777-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0001574	Process	Ganglioside biosynthetic process	IDA	10766765
GO:0001574	Process	Ganglioside biosynthetic process	IEA
GO:0003828	Function	Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	IBA
GO:0003828	Function	Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	IDA	9826427, 10766765, 26192331
GO:0003828	Function	Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	IEA
GO:0003828	Function	Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	TAS
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IBA
GO:0006486	Process	Protein glycosylation	IDA	10766765
GO:0006486	Process	Protein glycosylation	IEA
GO:0006491	Process	N-glycan processing	IBA
GO:0006491	Process	N-glycan processing	IDA	10766765, 26192331
GO:0006688	Process	Glycosphingolipid biosynthetic process	TAS	9073076
GO:0008373	Function	Sialyltransferase activity	IEA
GO:0009100	Process	Glycoprotein metabolic process	IDA	9826427, 10766765
GO:0009311	Process	Oligosaccharide metabolic process	IBA
GO:0009311	Process	Oligosaccharide metabolic process	IDA	10766765
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0033691	Function	Sialic acid binding	IC	9826427
GO:0042802	Function	Identical protein binding	IPI	26192331
GO:0097503	Process	Sialylation	IDA	9826427, 10766765, 26192331
GO:0097503	Process	Sialylation	IEA
GO:0097503	Process	Sialylation	ISS

Other IDs

• MIM: 609478
• HGNC: 14269
• e!Ensembl: ENSG00000177511

Protein

• UniProt ID: O43173
• Protein name: Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8-sialyltransferase III) (Ganglioside GD3 synthase ST8SIA3) (EC 2.4.3.8) (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (S
• Protein function: Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an acceptor, such as N-linked oligosaccharides of glycoproteins and glycolipids through alpha-2,
• PDB: 5BO6, 5BO7, 5BO8, 5BO9, 5CXY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00777	Glyco_transf_29	113 → 376	Glycosyltransferase family 29 (sialyltransferase)	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in fetal and adult brain and fetal liver. {ECO:0000269|PubMed:9826427}.
• Sequence:

  MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR
  SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS
  VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI
  DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG
  AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS
  TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF
  QLLYRMHGEGLTKLTLSHCA

• Sequence length: 380

Pathways

Reactome:

Sialic acid metabolism
N-Glycan antennae elongation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
HIV-1 INFECTION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Endometrial Neoplasms	Associate	35832124	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Associate	37511403	★☆☆☆☆ Found in Text Mining only