Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51008
Gene name Gene Name - the full gene name approved by the HGNC.	Activating signal cointegrator 1 complex subunit 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ASCC1
Synonyms (NCBI Gene) Gene synonyms aliases	ASC1p50, CGI-18, SMABF2, p50
Disease Acronyms (UniProt) Disease acronyms from UniProt database	SMABF2
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (

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SNP ID	Visualize variation	Clinical significance	Consequence
rs145940742	T>C	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, non coding transcript variant, 5 prime UTR variant
rs146370051	T>C	Benign, pathogenic, likely-benign	Coding sequence variant, missense variant, non coding transcript variant
rs183415577	G>A	Pathogenic	Coding sequence variant, non coding transcript variant, stop gained
rs747595523	C>T	Pathogenic	Splice donor variant
rs753324947	->C	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant
rs866050664	G>A	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1389098934	G>A,T	Pathogenic	Stop gained, coding sequence variant, intron variant, synonymous variant, non coding transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT714021	hsa-miR-6776-3p	HITS-CLIP	19536157
MIRT714020	hsa-miR-224-5p	HITS-CLIP	19536157
MIRT714019	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT714018	hsa-miR-6840-3p	HITS-CLIP	19536157
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT446510	hsa-miR-543	PAR-CLIP	22100165
MIRT446509	hsa-miR-451b	PAR-CLIP	22100165
MIRT446508	hsa-miR-15a-5p	PAR-CLIP	22100165
MIRT446507	hsa-miR-15b-5p	PAR-CLIP	22100165
MIRT446506	hsa-miR-16-5p	PAR-CLIP	22100165
MIRT446505	hsa-miR-195-5p	PAR-CLIP	22100165
MIRT446504	hsa-miR-424-5p	PAR-CLIP	22100165
MIRT446503	hsa-miR-497-5p	PAR-CLIP	22100165
MIRT446502	hsa-miR-6838-5p	PAR-CLIP	22100165
MIRT446501	hsa-miR-503-5p	PAR-CLIP	22100165
MIRT446500	hsa-miR-646	PAR-CLIP	22100165
MIRT446499	hsa-miR-335-5p	PAR-CLIP	22100165
MIRT446498	hsa-miR-4524a-5p	PAR-CLIP	22100165
MIRT446497	hsa-miR-4524b-5p	PAR-CLIP	22100165
MIRT446496	hsa-miR-1287-3p	PAR-CLIP	22100165
MIRT714021	hsa-miR-6776-3p	HITS-CLIP	19536157
MIRT714020	hsa-miR-224-5p	HITS-CLIP	19536157
MIRT714019	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT714018	hsa-miR-6840-3p	HITS-CLIP	19536157
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT615731	hsa-miR-548n	HITS-CLIP	23824327
MIRT615730	hsa-miR-548av-5p	HITS-CLIP	23824327
MIRT615729	hsa-miR-548k	HITS-CLIP	23824327
MIRT615728	hsa-miR-8054	HITS-CLIP	23824327
MIRT615727	hsa-miR-944	HITS-CLIP	23824327
MIRT615726	hsa-miR-8485	HITS-CLIP	23824327
MIRT615725	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT615724	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT615723	hsa-miR-603	HITS-CLIP	23824327
MIRT615722	hsa-miR-3941	HITS-CLIP	23824327
MIRT446510	hsa-miR-543	PAR-CLIP	22100165
MIRT446509	hsa-miR-451b	PAR-CLIP	22100165
MIRT446508	hsa-miR-15a-5p	PAR-CLIP	22100165
MIRT446507	hsa-miR-15b-5p	PAR-CLIP	22100165
MIRT446506	hsa-miR-16-5p	PAR-CLIP	22100165
MIRT446505	hsa-miR-195-5p	PAR-CLIP	22100165
MIRT446504	hsa-miR-424-5p	PAR-CLIP	22100165
MIRT446503	hsa-miR-497-5p	PAR-CLIP	22100165
MIRT446502	hsa-miR-6838-5p	PAR-CLIP	22100165
MIRT446501	hsa-miR-503-5p	PAR-CLIP	22100165
MIRT446500	hsa-miR-646	PAR-CLIP	22100165
MIRT446499	hsa-miR-335-5p	PAR-CLIP	22100165
MIRT446498	hsa-miR-4524a-5p	PAR-CLIP	22100165
MIRT446497	hsa-miR-4524b-5p	PAR-CLIP	22100165
MIRT446496	hsa-miR-1287-3p	PAR-CLIP	22100165
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT802585	hsa-miR-1323	CLIP-seq
MIRT802586	hsa-miR-3160-5p	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT802588	hsa-miR-4473	CLIP-seq
MIRT802589	hsa-miR-4639-5p	CLIP-seq
MIRT802590	hsa-miR-4676-5p	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802592	hsa-miR-4704-3p	CLIP-seq
MIRT802593	hsa-miR-4719	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT802597	hsa-miR-512-3p	CLIP-seq
MIRT802598	hsa-miR-520f	CLIP-seq
MIRT802599	hsa-miR-548aa	CLIP-seq
MIRT802600	hsa-miR-548o	CLIP-seq
MIRT802601	hsa-miR-575	CLIP-seq
MIRT802602	hsa-miR-1207-3p	CLIP-seq
MIRT802603	hsa-miR-4633-5p	CLIP-seq
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT802604	hsa-miR-184	CLIP-seq
MIRT802605	hsa-miR-3125	CLIP-seq
MIRT802606	hsa-miR-335	CLIP-seq
MIRT802607	hsa-miR-3545-3p	CLIP-seq
MIRT802608	hsa-miR-3622a-3p	CLIP-seq
MIRT802609	hsa-miR-3622b-3p	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT802610	hsa-miR-3916	CLIP-seq
MIRT802611	hsa-miR-4325	CLIP-seq
MIRT802612	hsa-miR-4480	CLIP-seq
MIRT802613	hsa-miR-4539	CLIP-seq
MIRT802590	hsa-miR-4676-5p	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802592	hsa-miR-4704-3p	CLIP-seq
MIRT802593	hsa-miR-4719	CLIP-seq
MIRT802614	hsa-miR-4724-5p	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT802615	hsa-miR-4804-5p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT802616	hsa-miR-522	CLIP-seq
MIRT802617	hsa-miR-548c-3p	CLIP-seq
MIRT802601	hsa-miR-575	CLIP-seq
MIRT802618	hsa-miR-642b	CLIP-seq
MIRT802619	hsa-miR-877	CLIP-seq
MIRT1936972	hsa-miR-1208	CLIP-seq
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT1936973	hsa-miR-1253	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT1936974	hsa-miR-1270	CLIP-seq
MIRT1936975	hsa-miR-1273f	CLIP-seq
MIRT802604	hsa-miR-184	CLIP-seq
MIRT1936976	hsa-miR-3146	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT1936977	hsa-miR-4251	CLIP-seq
MIRT1936978	hsa-miR-4310	CLIP-seq
MIRT1936979	hsa-miR-4436b-5p	CLIP-seq
MIRT802589	hsa-miR-4639-5p	CLIP-seq
MIRT802590	hsa-miR-4676-5p	CLIP-seq
MIRT1936980	hsa-miR-4683	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802592	hsa-miR-4704-3p	CLIP-seq
MIRT1936981	hsa-miR-4712-3p	CLIP-seq
MIRT802593	hsa-miR-4719	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT1936982	hsa-miR-4802-5p	CLIP-seq
MIRT802615	hsa-miR-4804-5p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT802599	hsa-miR-548aa	CLIP-seq
MIRT1936983	hsa-miR-548ac	CLIP-seq
MIRT1936984	hsa-miR-548d-3p	CLIP-seq
MIRT1936985	hsa-miR-548z	CLIP-seq
MIRT802601	hsa-miR-575	CLIP-seq
MIRT1936986	hsa-miR-620	CLIP-seq
MIRT802618	hsa-miR-642b	CLIP-seq
MIRT1936972	hsa-miR-1208	CLIP-seq
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT802585	hsa-miR-1323	CLIP-seq
MIRT2176770	hsa-miR-224	CLIP-seq
MIRT1936976	hsa-miR-3146	CLIP-seq
MIRT802607	hsa-miR-3545-3p	CLIP-seq
MIRT802608	hsa-miR-3622a-3p	CLIP-seq
MIRT802609	hsa-miR-3622b-3p	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT1936978	hsa-miR-4310	CLIP-seq
MIRT2176771	hsa-miR-4421	CLIP-seq
MIRT1936979	hsa-miR-4436b-5p	CLIP-seq
MIRT802613	hsa-miR-4539	CLIP-seq
MIRT802589	hsa-miR-4639-5p	CLIP-seq
MIRT802590	hsa-miR-4676-5p	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802592	hsa-miR-4704-3p	CLIP-seq
MIRT802593	hsa-miR-4719	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT802599	hsa-miR-548aa	CLIP-seq
MIRT802600	hsa-miR-548o	CLIP-seq
MIRT802601	hsa-miR-575	CLIP-seq
MIRT802618	hsa-miR-642b	CLIP-seq
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT1936976	hsa-miR-3146	CLIP-seq
MIRT802608	hsa-miR-3622a-3p	CLIP-seq
MIRT802609	hsa-miR-3622b-3p	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT802589	hsa-miR-4639-5p	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT802618	hsa-miR-642b	CLIP-seq
MIRT1936972	hsa-miR-1208	CLIP-seq
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT2480142	hsa-miR-132	CLIP-seq
MIRT802585	hsa-miR-1323	CLIP-seq
MIRT2480143	hsa-miR-144	CLIP-seq
MIRT2480144	hsa-miR-212	CLIP-seq
MIRT2176770	hsa-miR-224	CLIP-seq
MIRT1936976	hsa-miR-3146	CLIP-seq
MIRT802607	hsa-miR-3545-3p	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT1936977	hsa-miR-4251	CLIP-seq
MIRT2480145	hsa-miR-4307	CLIP-seq
MIRT1936978	hsa-miR-4310	CLIP-seq
MIRT802611	hsa-miR-4325	CLIP-seq
MIRT1936979	hsa-miR-4436b-5p	CLIP-seq
MIRT802613	hsa-miR-4539	CLIP-seq
MIRT802589	hsa-miR-4639-5p	CLIP-seq
MIRT2480146	hsa-miR-4645-3p	CLIP-seq
MIRT802590	hsa-miR-4676-5p	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802592	hsa-miR-4704-3p	CLIP-seq
MIRT1936981	hsa-miR-4712-3p	CLIP-seq
MIRT802593	hsa-miR-4719	CLIP-seq
MIRT802614	hsa-miR-4724-5p	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT2480147	hsa-miR-496	CLIP-seq
MIRT802616	hsa-miR-522	CLIP-seq
MIRT802599	hsa-miR-548aa	CLIP-seq
MIRT1936983	hsa-miR-548ac	CLIP-seq
MIRT802617	hsa-miR-548c-3p	CLIP-seq
MIRT1936984	hsa-miR-548d-3p	CLIP-seq
MIRT802600	hsa-miR-548o	CLIP-seq
MIRT1936985	hsa-miR-548z	CLIP-seq
MIRT2480148	hsa-miR-567	CLIP-seq
MIRT802601	hsa-miR-575	CLIP-seq
MIRT2480149	hsa-miR-580	CLIP-seq
MIRT802618	hsa-miR-642b	CLIP-seq
MIRT1936972	hsa-miR-1208	CLIP-seq
MIRT802582	hsa-miR-1224-5p	CLIP-seq
MIRT802583	hsa-miR-1255a	CLIP-seq
MIRT802584	hsa-miR-1255b	CLIP-seq
MIRT2480142	hsa-miR-132	CLIP-seq
MIRT802585	hsa-miR-1323	CLIP-seq
MIRT2480143	hsa-miR-144	CLIP-seq
MIRT2480144	hsa-miR-212	CLIP-seq
MIRT2176770	hsa-miR-224	CLIP-seq
MIRT1936976	hsa-miR-3146	CLIP-seq
MIRT802607	hsa-miR-3545-3p	CLIP-seq
MIRT802587	hsa-miR-3915	CLIP-seq
MIRT1936977	hsa-miR-4251	CLIP-seq
MIRT2480145	hsa-miR-4307	CLIP-seq
MIRT1936978	hsa-miR-4310	CLIP-seq
MIRT802611	hsa-miR-4325	CLIP-seq
MIRT1936979	hsa-miR-4436b-5p	CLIP-seq
MIRT802613	hsa-miR-4539	CLIP-seq
MIRT802589	hsa-miR-4639-5p	CLIP-seq
MIRT2480146	hsa-miR-4645-3p	CLIP-seq
MIRT802590	hsa-miR-4676-5p	CLIP-seq
MIRT802591	hsa-miR-4689	CLIP-seq
MIRT802592	hsa-miR-4704-3p	CLIP-seq
MIRT1936981	hsa-miR-4712-3p	CLIP-seq
MIRT802593	hsa-miR-4719	CLIP-seq
MIRT802614	hsa-miR-4724-5p	CLIP-seq
MIRT802594	hsa-miR-4751	CLIP-seq
MIRT802595	hsa-miR-4802-3p	CLIP-seq
MIRT802596	hsa-miR-490-5p	CLIP-seq
MIRT2480147	hsa-miR-496	CLIP-seq
MIRT802616	hsa-miR-522	CLIP-seq
MIRT802599	hsa-miR-548aa	CLIP-seq
MIRT802617	hsa-miR-548c-3p	CLIP-seq
MIRT802600	hsa-miR-548o	CLIP-seq
MIRT2480148	hsa-miR-567	CLIP-seq
MIRT802601	hsa-miR-575	CLIP-seq
MIRT2480149	hsa-miR-580	CLIP-seq
MIRT802618	hsa-miR-642b	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IDA	12077347, 26924529
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IDA	12077347
GO:0006307	Process	DNA dealkylation involved in DNA repair	TAS
GO:0006355	Process	Regulation of transcription, DNA-templated	IDA	12077347
GO:0016607	Component	Nuclear speck	IEA
GO:0031594	Component	Neuromuscular junction	IMP	26924529

MIM	HGNC	e!Ensembl
614215	24268	ENSG00000138303

Protein

UniProt ID

Q8N9N2

Protein name

Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)

Protein function

Plays a role in DNA damage repair as component of the ASCC complex (PubMed:29997253). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). In cells responding to gastrin-activated paracrine signals,

PDB

8TLY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00013	KH_1	92 → 149	KH domain	Domain
PF10469	AKAP7_NLS	161 → 378		Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:12077347}.

Sequence

MEVLRPQLIRIDGRNYRKNPVQEQTYQHEEDEEDFYQGSMECADEPCDAYEVEQTPQGFR
STLRAPSLLYNLIHLNTSNDCGFQKITLDCQNIYTWKSRHIVGKRGDTRKKIEMETKTSI
SIPKPGQDGEIVITGQHRNGVISARTRIDVLLDTFRRKQPFTHFLAFFLNEVEVQEGFLR
FQEEVLAKCSMDHGVDSSIFQNPKKLHLTIGMLVLLSEEEIQQTCEMLQQCKEEFINDIS
GGKPLEVEMAGIEYMNDDPGMVDVLYAKVHMKDGSNRLQELVDRVLERFQASGLIVKEWN
SVKLHATVMNTLFRKDPNAEGRYNLYTAEGKYIFKERESFDGRNILKSFALLPRLEYNDA
ISAHCNLCLPGSSDSPASASQVAGITGVSDAYSQSLPGKS

Sequence length

400

Interactions

View interactions

	Reactome
			ALKBH3 mediated reversal of alkylation damage

Show/Hide Causal Diseases (6)

Disease term	Disease name	dbSNP ID	References
Causal
Arthrogryposis multiplex congenita	Arthrogryposis	rs1586285494, rs80358233, rs137853305, rs1559154278, rs398124167, rs398124172, rs587780399, rs786204576, rs786204430, rs769345284, rs749355583, rs793888524, rs793888525, rs878854368, rs555445835 View all (138 more)	28749478
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291 View all (32 more)
Esophageal carcinoma	Esophageal carcinoma	rs121912967
Patent ductus arteriosus	Patent ductus arteriosus	rs80338911, rs879253870, rs879253871, rs879255278, rs879255279, rs879253872
Spinal muscular atrophy	Spinal Muscular Atrophy	rs104893922, rs1554066397, rs77804083, rs104893930, rs104893927, rs104893935, rs387906738, rs398123028, rs371707778, rs398123030, rs587780564, rs713993043, rs727505393, rs797044855, rs863223361 View all (22 more)	28749478
Spinal muscular atrophy with congenital bone fractures	SPINAL MUSCULAR ATROPHY WITH CONGENITAL BONE FRACTURES 2, Prenatal-onset spinal muscular atrophy with congenital bone fractures	rs869312827, rs761865592, rs753324947, rs147303485, rs747595523, rs183415577, rs866050664, rs1389098934	28749478

Show/Hide Unknown Diseases (6)

Disease term	Disease name	Source
Unknown
Barrett esophagus	Barrett Esophagus, NON RARE IN EUROPE: Barrett esophagus	ClinVar
Pulmonary hypoplasia	Congenital hypoplasia of lung	ClinVar
Peripheral axonal neuropathy	Peripheral axonal neuropathy	ClinVar
Dementia	Dementia	GWAS
Alzheimer disease	Alzheimer disease	GWAS
Sarcoidosis	Sarcoidosis	GWAS

Show/Hide Text Mining Associations (18)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	21791690
Arthrogryposis	Associate	33931933
Barrett Esophagus	Associate	21791690
Blood Coagulation Disorders Inherited	Associate	33931933
Bone Diseases	Associate	37455927
Femoral Fractures Distal	Associate	37455927
Fractures Bone	Associate	38143368
Head and Neck Neoplasms	Associate	35460558
Microphthalmia Syndromic 10	Associate	37455927
Muscle Hypotonia	Associate	37455927
Muscular Atrophy Spinal	Associate	38143368
Muscular Diseases	Associate	38143368
Musculoskeletal Diseases	Associate	37455927
Osteoporosis pseudoglioma syndrome	Associate	37455927
Polycythemia	Associate	18793248
Respiratory Insufficiency	Associate	37455927
Spinal Muscular Atrophies of Childhood	Associate	38143368
Spinal Muscular Atrophy Type I with Congenital Bone Fractures	Associate	32160656, 33931933, 37455927

ASCC1 (activating signal cointegrator 1 complex subunit 1)