Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	51000
Gene name	Solute carrier family 35 member B3
Gene symbol	SLC35B3
Synonyms (NCBI Gene)	C6orf196CGI-19PAPST2
Chromosome	6
Chromosome location	6p24.3
Summary	This gene is a member of the solute carrier family. The encoded protein is involved in the transport of 3-prime phosphoadenosine 5-prime phosphosulfate (PAPS) from the nucleus or the cytosol to the Golgi lumen. This gene has been reported to be expressed

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miRTarBase ID	miRNA	Experiments	Reference
MIRT000908	hsa-miR-15a-5p	Microarray	18362358
MIRT000907	hsa-miR-16-5p	Microarray	18362358
MIRT653594	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT653593	hsa-miR-3908	HITS-CLIP	23824327
MIRT653592	hsa-miR-488-5p	HITS-CLIP	23824327
MIRT653591	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT653590	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT653589	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT653588	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT653587	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT653586	hsa-miR-29b-2-5p	HITS-CLIP	23824327
MIRT653585	hsa-miR-659-3p	HITS-CLIP	23824327
MIRT653584	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT653583	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT653582	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653581	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653580	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT653579	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT653578	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT653577	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT653576	hsa-miR-548n	HITS-CLIP	23824327
MIRT653575	hsa-miR-548az-5p	HITS-CLIP	23824327
MIRT653574	hsa-miR-548t-5p	HITS-CLIP	23824327
MIRT653573	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT653572	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT653571	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT653570	hsa-miR-5697	HITS-CLIP	23824327
MIRT653569	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT653568	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT653567	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT653566	hsa-miR-1297	HITS-CLIP	23824327
MIRT653565	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT653564	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT653562	hsa-miR-4465	HITS-CLIP	23824327
MIRT653563	hsa-miR-498	HITS-CLIP	23824327
MIRT653561	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT653560	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT653559	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT653594	hsa-miR-9-5p	HITS-CLIP	23824327
MIRT653593	hsa-miR-3908	HITS-CLIP	23824327
MIRT653592	hsa-miR-488-5p	HITS-CLIP	23824327
MIRT653591	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT653590	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT653589	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT653588	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT653587	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT653586	hsa-miR-29b-2-5p	HITS-CLIP	23824327
MIRT653585	hsa-miR-659-3p	HITS-CLIP	23824327
MIRT653584	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT653583	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT653582	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653581	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653580	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT653579	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT653578	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT653577	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT653576	hsa-miR-548n	HITS-CLIP	23824327
MIRT653575	hsa-miR-548az-5p	HITS-CLIP	23824327
MIRT653574	hsa-miR-548t-5p	HITS-CLIP	23824327
MIRT653573	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT653572	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT653571	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT653570	hsa-miR-5697	HITS-CLIP	23824327
MIRT653569	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT653568	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT653567	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT653566	hsa-miR-1297	HITS-CLIP	23824327
MIRT653565	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT653564	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT653562	hsa-miR-4465	HITS-CLIP	23824327
MIRT653563	hsa-miR-498	HITS-CLIP	23824327
MIRT653561	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT653560	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT653559	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT1360331	hsa-miR-105	CLIP-seq
MIRT1360332	hsa-miR-374a	CLIP-seq
MIRT1360333	hsa-miR-374b	CLIP-seq
MIRT1360334	hsa-miR-3925-3p	CLIP-seq
MIRT1360335	hsa-miR-4704-3p	CLIP-seq
MIRT1360336	hsa-miR-4768-5p	CLIP-seq
MIRT1360337	hsa-miR-766	CLIP-seq
MIRT1553769	hsa-miR-204	CLIP-seq
MIRT1553770	hsa-miR-211	CLIP-seq
MIRT2106654	hsa-miR-1910	CLIP-seq
MIRT1553769	hsa-miR-204	CLIP-seq
MIRT1553770	hsa-miR-211	CLIP-seq
MIRT2106655	hsa-miR-361-5p	CLIP-seq
MIRT2106656	hsa-miR-3942-5p	CLIP-seq
MIRT2106657	hsa-miR-3978	CLIP-seq
MIRT2106658	hsa-miR-431	CLIP-seq
MIRT2106659	hsa-miR-4474-5p	CLIP-seq
MIRT2106660	hsa-miR-4643	CLIP-seq
MIRT2106661	hsa-miR-4662a-5p	CLIP-seq
MIRT2106662	hsa-miR-4703-5p	CLIP-seq
MIRT2106663	hsa-miR-4717-3p	CLIP-seq
MIRT2106664	hsa-miR-4719	CLIP-seq
MIRT2106665	hsa-miR-4766-3p	CLIP-seq
MIRT2106666	hsa-miR-659	CLIP-seq
MIRT2106667	hsa-miR-9	CLIP-seq
MIRT2106654	hsa-miR-1910	CLIP-seq
MIRT1553769	hsa-miR-204	CLIP-seq
MIRT1553770	hsa-miR-211	CLIP-seq
MIRT2330928	hsa-miR-2114	CLIP-seq
MIRT2106655	hsa-miR-361-5p	CLIP-seq
MIRT2106657	hsa-miR-3978	CLIP-seq
MIRT2330929	hsa-miR-455-3p	CLIP-seq
MIRT1360335	hsa-miR-4704-3p	CLIP-seq
MIRT2106664	hsa-miR-4719	CLIP-seq
MIRT2106656	hsa-miR-3942-5p	CLIP-seq
MIRT2106662	hsa-miR-4703-5p	CLIP-seq
MIRT2106664	hsa-miR-4719	CLIP-seq
MIRT2106665	hsa-miR-4766-3p	CLIP-seq
MIRT2106654	hsa-miR-1910	CLIP-seq
MIRT1553769	hsa-miR-204	CLIP-seq
MIRT1553770	hsa-miR-211	CLIP-seq
MIRT2330928	hsa-miR-2114	CLIP-seq
MIRT2106655	hsa-miR-361-5p	CLIP-seq
MIRT2106656	hsa-miR-3942-5p	CLIP-seq
MIRT2106657	hsa-miR-3978	CLIP-seq
MIRT2330929	hsa-miR-455-3p	CLIP-seq
MIRT2106662	hsa-miR-4703-5p	CLIP-seq
MIRT2106664	hsa-miR-4719	CLIP-seq
MIRT2106665	hsa-miR-4766-3p	CLIP-seq
MIRT2106666	hsa-miR-659	CLIP-seq
MIRT2106667	hsa-miR-9	CLIP-seq
MIRT2106654	hsa-miR-1910	CLIP-seq
MIRT1553769	hsa-miR-204	CLIP-seq
MIRT1553770	hsa-miR-211	CLIP-seq
MIRT2330928	hsa-miR-2114	CLIP-seq
MIRT2106655	hsa-miR-361-5p	CLIP-seq
MIRT2106656	hsa-miR-3942-5p	CLIP-seq
MIRT2106657	hsa-miR-3978	CLIP-seq
MIRT2330929	hsa-miR-455-3p	CLIP-seq
MIRT2106662	hsa-miR-4703-5p	CLIP-seq
MIRT2106664	hsa-miR-4719	CLIP-seq
MIRT2106665	hsa-miR-4766-3p	CLIP-seq
MIRT2106666	hsa-miR-659	CLIP-seq
MIRT2106667	hsa-miR-9	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA
GO:0000139	Component	Golgi membrane	IDA	16492677
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0015297	Function	Antiporter activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0046963	Process	3'-phosphoadenosine 5'-phosphosulfate transport	IBA
GO:0046964	Function	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	IBA
GO:0046964	Function	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	IDA	16492677
GO:0046964	Function	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	TAS
GO:0055085	Process	Transmembrane transport	IBA
GO:0055085	Process	Transmembrane transport	IEA
GO:1902558	Process	5'-adenylyl sulfate transmembrane transport	TAS
GO:1902559	Process	3'-phospho-5'-adenylyl sulfate transmembrane transport	IEA

MIM	HGNC	e!Ensembl
610845	21601	ENSG00000124786

Q9H1N7

Protein name

Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (3'-phosphoadenosine 5'-phosphosulfate transporter) (PAPS transporter 2) (Solute carrier family 35 member B3)

Protein function

Probably functions as a 3'-phosphoadenylyl sulfate:adenosine 3',5'-bisphosphate antiporter at the Golgi membranes. Mediates the transport from the cytosol into the lumen of the Golgi of 3'-phosphoadenylyl sulfate/adenosine 3'-phospho 5'-phosphos

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08449	UAA	80 → 371	UAA transporter family	Family

Tissue specificity

TISSUE SPECIFICITY: Preferentially and highly expressed in colon. {ECO:0000269|PubMed:16492677}.

Sequence

MDLTQQAKDIQNITVQETNKNNSESIECSKITMDLKFNNSRKYISITVPSKTQTMSPHIK
SVDDVVVLGMNLSKFNKLTQFFICVAGVFVFYLIYGYLQELIFSVEGFKSCGWYLTLVQF
AFYSIFGLIELQLIQDKRRRIPGKTYMIIAFLTVGTMGLSNTSLGYLNYPTQVIFKCCKL
IPVMLGGVFIQGKRYNVADVSAAICMSLGLIWFTLADSTTAPNFNLTGVVLISLALCADA
VIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLGLTCTSGLGPAVTFCAKNPVRTYGYA
FLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKAMTIVLSFIFFAKPFTFQYVWSGLLV
VLGIFLNVYSKNMDKIRLPSLYDLINKSVEARKSRTLAQTV

Sequence length

401

Interactions

View interactions

	Reactome
			Transport and synthesis of PAPS Transport of nucleotide sugars

SLC35B3 (solute carrier family 35 member B3)