Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
50999
Gene name Gene Name - the full gene name approved by the HGNC.
Transmembrane p24 trafficking protein 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TMED5
Synonyms (NCBI Gene) Gene synonyms aliases
CGI-100, p24g2, p28
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p22.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019961 hsa-miR-375 Microarray 20215506
MIRT028593 hsa-miR-30a-5p Proteomics 18668040
MIRT029986 hsa-miR-26b-5p Microarray 19088304
MIRT032422 hsa-let-7b-5p Proteomics 18668040
MIRT046138 hsa-miR-30b-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 23455924, 32296183
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0005793 Component Endoplasmic reticulum-Golgi intermediate compartment IBA 21873635
GO:0005793 Component Endoplasmic reticulum-Golgi intermediate compartment IDA 15308636, 19948005
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616876 24251 ENSG00000117500
Protein
UniProt ID Q9Y3A6
Protein name Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28)
Protein function Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicl
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01105 EMP24_GP25L 35 222 emp24/gp25L/p24 family/GOLD Domain
Sequence
Sequence length 229
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    WNT ligand biogenesis and trafficking
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 36530030
Ovarian Neoplasms Associate 36657061
Uterine Cervical Neoplasms Associate 36530030