Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
50937
Gene name Gene Name - the full gene name approved by the HGNC.
Cell adhesion associated, oncogene regulated
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CDON
Synonyms (NCBI Gene) Gene synonyms aliases
CDO, CDON1, HPE11, Ihog, ORCAM
Disease Acronyms (UniProt) Disease acronyms from UniProt database
HPE11
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q24.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor
SNPs SNP information provided by dbSNP.
SNP ID Visualize variation Clinical significance Consequence
rs141081456 C>G Conflicting-interpretations-of-pathogenicity, uncertain-significance Coding sequence variant, non coding transcript variant, missense variant
rs369673018 T>G Pathogenic Missense variant, coding sequence variant, non coding transcript variant
rs387906995 G>A,C Pathogenic, likely-pathogenic Missense variant, coding sequence variant, non coding transcript variant
rs387906996 A>T Pathogenic Missense variant, coding sequence variant, non coding transcript variant
rs387906997 T>C Pathogenic Missense variant, coding sequence variant, non coding transcript variant
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019131 hsa-miR-335-5p Microarray 18185580
MIRT023201 hsa-miR-124-3p Microarray 18668037
MIRT025580 hsa-miR-34a-5p Sequencing 20371350
MIRT026933 hsa-miR-192-5p Microarray 19074876
MIRT027875 hsa-miR-96-5p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001708 Process Cell fate specification IEA
GO:0001934 Process Positive regulation of protein phosphorylation IEA
GO:0002088 Process Lens development in camera-type eye IEA
GO:0005515 Function Protein binding IPI 11782431, 18794898, 19470755, 20519495, 21802063
GO:0005886 Component Plasma membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608707 17104 ENSG00000064309
Protein
UniProt ID Q4KMG0
Protein name Cell adhesion molecule-related/down-regulated by oncogenes
Protein function Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).
PDB 3D1M , 3N1F , 3N1Q
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13927 Ig_3 28 101 Domain
PF13927 Ig_3 221 294 Domain
PF07679 I-set 312 397 Immunoglobulin I-set domain Domain
PF13927 Ig_3 404 504 Domain
PF00041 fn3 578 667 Fibronectin type III domain Domain
PF00041 fn3 722 807 Fibronectin type III domain Domain
PF00041 fn3 826 916 Fibronectin type III domain Domain
Sequence
MHPDLGPLCTLLYVTLTILCSSVSSDLAPYFTSEPLSAVQKLGGPVVLHCSAQPVTTRIS
WLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLANN
SIGAIVSGPATVSVAVLGD
FGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSGNLQILN
VSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQALAVLSRSPVT
LECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGN
KSGDVK
YVTYMVNVLEHASISKGLQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLT
AGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEI
ENDGGFKPVIITAPVSAKVADGD
FVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQA
GASSLHIQAVTQEHAGKYICEAAN
EHGTTQAEASLMVVPFETNTKAETVTLPDAAQNDDR
SKRDGSETGLLSSFPVKVHPSAVESAPEKNASGISVPDAPIILSPPQTHTPDTYNLVWRA
GKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYEVLMVARSA
AGEGQPA
MLTFRTSKEKTASSKNTQASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGV
PEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLSV
EVRSLEPGSTYKFRVIAINHYGESFRS
SASRPYQVVGFPNRFSSRPITGPHIAYTEAVSD
TQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSY
DIKMQCFNEGGESEFS
NVMICETKVKRVPGASEYPVKDLSTPPNSLGSGGNVGPATSPAR
SSDMLYLIVGCVLGVMVLILMVFIAMCLWKNRQQNTIQKYDPPGYLYQGSDMNGQMVDYT
TLSGASQINGNVHGGFLTNGGLSSGYSHLHHKVPNAVNGIVNGSLNGGLYSGHSNSLTRT
HVDFEHPHHLVNGGGMYTAVPQIDPLECVNCRNCRNNNRCFTKTNSTFSSSPPPVVPVVA
PYPQDGLEMKPLSHVKVPVCLTSAVPDCGQLPEESVKDNVEPVPTQRTCCQDIVNDVSSD
GSEDPAEFSRGQEGMINLRIPDHLQLAKSCVWEGDSCAHSETEINIVSWNALILPPVPEG
CAEKTMWSPPGIPLDSPTEVLQQPRET
Sequence length 1287
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Hedgehog signaling pathway   Myogenesis
Ligand-receptor interactions
Activation of SMO
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Agenesis of corpus callosum Agenesis of corpus callosum rs754914260, rs1057519053, rs1057519056, rs1057519054, rs1057519055, rs1057519057, rs1384496494, rs1599017933
Cryptorchidism Cryptorchidism rs121912555, rs104894697, rs104894698, rs398122886
Developmental delay Global developmental delay rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291
View all (32 more)
Diabetes insipidus Diabetes Insipidus rs781942628, rs104894747, rs104894748, rs104894749, rs104894750, rs28935496, rs2147483647, rs104894751, rs104894752, rs104894753, rs104894754, rs104894755, rs1569545523, rs104894756, rs104894757
View all (33 more)
Unknown
Disease term Disease name Evidence References Source
Ambiguous genitalia Ambiguous Genitalia ClinVar
Asthma Asthma ClinVar
Pituitary stalk interruption syndrome Pituitary stalk interruption syndrome 26529631 ClinVar
Pituitary Stalk Interruption Syndrome pituitary stalk interruption syndrome GenCC
Associations from Text Mining
Disease Name Relationship Type References
Abducens Nerve Diseases Associate 34235642
Anophthalmia with pulmonary hypoplasia Associate 32799327
Cranial Nerve Diseases Associate 34235642
Growth Disorders Associate 34235642
Holoprosencephaly Associate 21995818, 34235642
Idiopathic Hypogonadotropic Hypogonadism Associate 33208564
Ovarian Neoplasms Associate 39972314
Paget Disease Extramammary Associate 34895219
Pituitary Diseases Associate 34235642