PBX2 (PBX homeobox 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5089 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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PBX homeobox 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PBX2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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G17, HOX12, PBX2MHC |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.32 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | P40425 | |||||||||||||||
| Protein name | Pre-B-cell leukemia transcription factor 2 (Homeobox protein PBX2) (Protein G17) | |||||||||||||||
| Protein function | Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1. | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitously expressed. | |||||||||||||||
| Sequence |
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| Sequence length | 430 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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