Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5089
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Gene name
Gene Name - the full gene name approved by the HGNC.
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PBX homeobox 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PBX2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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G17, HOX12, PBX2MHC |
Chromosome
Chromosome number
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6 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.32 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Age-related macular degeneration |
Age related macular degeneration |
rs199474657, rs61750120, rs1800728, rs62654397, rs61749423, rs61751412, rs61749439, rs61751398, rs61752417, rs62645946, rs1801269, rs62646860, rs61750142, rs61750145, rs61750152, rs61751377, rs61753029, rs61751407, rs61751389, rs61750645, rs61750648, rs879255520, rs752147871, rs886044750, rs886044749, rs746541266, rs756840095, rs886044725, rs749526785, rs1057518955, rs1057518767, rs371489809, rs1064793014, rs1571264574, rs1659524475 View all (20 more) |
26691988 |
Rheumatoid arthritis |
Rheumatoid Arthritis |
rs587776843 |
17804836, 21156761 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
28540026 |
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Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Asthma |
Asthma |
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21804548 |
ClinVar, GWAS |
Dermatitis |
Dermatitis |
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GWAS |
Rheumatic Heart Disease |
Rheumatic Heart Disease |
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GWAS |
Coronary artery disease |
Coronary artery disease |
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GWAS |
Cervical Cancer |
Cervical Cancer |
Our screens identified 10 miRNAs that enhance fitness of HeLa cells and have been reported to be up-regulated in cervical cancer (Table2). |
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GWAS, CBGDA |
Anxiety Disorder |
Anxiety Disorder |
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GWAS |
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