Gene Gene information from NCBI Gene database.
Entrez ID 50809
Gene name Heterochromatin protein 1 binding protein 3
Gene symbol HP1BP3
Synonyms (NCBI Gene)
HP1-BP74HP1BP74
Chromosome 1
Chromosome location 1p36.12
miRNA miRNA information provided by mirtarbase database.
637
miRTarBase ID miRNA Experiments Reference
MIRT024041 hsa-miR-1-3p Proteomics 18668040
MIRT048364 hsa-miR-29b-3p CLASH 23622248
MIRT041380 hsa-miR-193b-3p CLASH 23622248
MIRT714373 hsa-miR-6757-3p HITS-CLIP 19536157
MIRT714372 hsa-miR-1228-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
GO ID Ontology Definition Evidence Reference
GO:0000786 Component Nucleosome IEA
GO:0003677 Function DNA binding IBA
GO:0003677 Function DNA binding IDA 20042602
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 20042602, 25416956, 30021884, 33961781
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616072 24973 ENSG00000127483
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5SSJ5
Protein name Heterochromatin protein 1-binding protein 3 (Protein HP1-BP74)
Protein function Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation during hy
PDB 2RQP
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00538 Linker_histone 158 231 linker histone H1 and H5 family Domain
PF00538 Linker_histone 257 329 linker histone H1 and H5 family Domain
PF00538 Linker_histone 341 412 linker histone H1 and H5 family Domain
Sequence
MATDTSQGELVHPKALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEG
EEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKD
QSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASV
VAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVV
QKSRKTPQK
SRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQL
LKNALQRAVERGQLEQITGKGASGTFQLK
KSGEKPLLGGSLMEYAILSAIAAMNEPKTCS
TTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLC
FPYYPSPG
VLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPA
PKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGK
GKSTMKKSFRVKK
Sequence length 553
Interactions View interactions